INTRODUCTION

https://cpt.snu.ac.kr/en/Introduction/Facilities URL COPY

Clinical Trials Center

Seoul National University Hospital Clinical Trial Center was established in 1995 to advance the domestic clinical research and to improve efficiency. It provides optimal research environment to conduct scientific and ethical clinical trials according to Korean good clinical practice (KGCP) of the Ministry of Health and Welfare, and international standards such as ICH and FDA Guidelines.

Researchers with appropriate quality for Industry-Academia collaborative research, including researchers in department of clinical pharmacology and therapeutics at Seoul National University College of Medicine, can take advantage of this center. This center is a facility for improving the ethical and scientific quality of clinical research and Industry-Academia collaborative research and for conducting clinical trials efficiently. It provides a researcher, research facilities, and administrative support to perform the research of efficacy, stability and action mechanism of various medicines including new drugs,. It serves as a coordinating center for post-marketing surveillance and multi-center collaborative research.

Medical Office (SNUCPT Office)

Medical Office is the place where all the members of SNUCPT stay. Here, members of SNUCPT conduct all tasks related to clinical trials, including new drug development and clinical trials, and analysis and reporting of results. In addition, a variety of consultation is carried out, including TDM, personalized medication therapy, and pharmacokinetics/pharmacodynamics.

Biological sample analysis team

Biological sample analysis team analyzes the concentration of medicines and metabolites using a variety of analytical instruments based on accumulated experience and analytical techniques. In addition, this team explore circulating biomarkers (mRNA, microRNA), and conduct endogenous metabolomic studies and genotype analysis for optimal drug therapy, and prediction of drug interaction or drug effect.

Genome analysis
Genomic research
  • Genotype analysis
  • DMET(Drug Metabolizing Enzymes and Transporters)
  • Microarray
Real-Time PCR
  • Applied Biosystems SDS 7500
Metabolome analysis
Metabolomics
  • Metabolite identification
  • Drug metabolism research
Q-TOF System
  • Waters Synapt G2-S HDMS
  • Waters Xevo G2 Q-TOF
  • Agilent 6530 Q-TOF
GC-MS System
  • Agilent 7890B-7693
Analysis of drug concentration
Small molecule drug analysis
  • Analysis method development
  • Analysis method validation
  • Sample analysis
LC-MS/MS System
  • AB SCIEX API4000
  • AB SCIEX API4000 QTRAP
  • Waters Xevo TQ
  • Agilent 6460
  • Agilent 6490
High molecule drug analysis
  • LBA(Ligand Binding Assay)
  • immunogenic assessment
Microplate Reader
  • Molecular Devices M2e
  • Molecular Devices VersaMax

Clinical Research Software

We use a variety of softwares such as Phoenix WinNonlin® and NONMEM® for pharmacokinetic, pharmacodynamic and statistical analysis of the results obtained from clinical trials.