SNUCPT

Exploration of smart adherence-monitoring methods in vitamin D-deficient patients: A pilot feasibility clinical study

Ki Young Huh, Hwiwon Lee, SeungHwan Lee, Kyung-Sang Yu, Kyung Hwan Kim, Heejin Kim

Clinical and translational science. 2023,Oct;16(10):1866-1875. doi: 10.1111/cts.13594. Epub 2023 Jul 24.

Pharmacokinetic and pharmacodynamic exploration of various combinations of tegoprazan immediate and delayed-release formulations

Sooyoun Park, Eunsol Yang, Byungwook Kim, Jihoon Kwon, In-Jin Jang, Seung Hwan Lee

British journal of clinical pharmacology. 2023,Sep;89(9):2877-2887. doi: 10.1111/bcp.15784. Epub 2023 Jun 1.

Semimechanistic pharmacokinetic-pharmacodynamic model of tripegfilgrastim for pediatric patients after chemotherapy

Soyoung Lee, Kyung Taek Hong, In-Jin Jang, Kyung-Sang Yu, Hyoung Jin Kang, Jaeseong Oh

CPT: pharmacometrics & systems pharmacology. 2023,Sep;;12(9):1319-1334. doi: 10.1002/psp4.13012. Epub 2023 Aug 9.

Immunogenicity and safety of SARS-CoV-2 recombinant protein nanoparticle vaccine GBP510 adjuvanted with AS03: interim results of a randomised, active-controlled, observer-blinded, phase 3 trial

Joon Young Song, Won Suk Choi, Jung Yeon Heo, Eun Jin Kim, Jin Soo Lee, Dong Sik Jung, Shin-Woo Kim, Kyung-Hwa Park, Joong Sik Eom, Su Jin Jeong, Jacob Lee, Ki Tae Kwon, Hee Jung Choi, Jang Wook Sohn, Young Keun Kim, Byung Wook Yoo, In-Jin Jang, Maria Z Caped

EClinicalMedicine. 2023,Sep;7:64:102140. doi: 10.1016/j.eclinm.2023.102140. eCollection 2023 Oct.

Effect of Food on the Pharmacokinetics and Pharmacodynamics of a Novel Dual Delayed-Release Formulation of Esomeprazole in Healthy Subjects

Sejung Hwang, Sung Hee Hong, Jina Jung, Jae-Yong Chung, In-Jin Jang, SeungHwan Lee

Clinical pharmacology in drug development. 2023,Aug;12(8):839-844. doi: 10.1002/cpdd.1237. Epub 2023 Mar 16.

Feasibility study for a fully decentralized clinical trial in participants with functional constipation symptoms

Ki Young Huh, Woo Kyung Chung, Jiyeon Park, SeungHwan Lee, Min-Gul Kim, Jaeseong Oh, Kyung-Sang Yu

Clinical and translational science. 2023,Aug;25. doi: 10.1111/cts.13617. Online ahead of print.

Pharmacokinetic Comparison Between a Fixed-Dose Combination of Empagliflozin L-Proline/Metformin and Empagliflozin/Metformin in Healthy Korean Subjects

HyunJoon Lee, Jae-Yong Chung, Kyung-Sang Yu, Shin-Jung Park, Soyoung Lee

Clinical pharmacology in drug development. 2023,Jul;25. doi: 10.1002/cpdd.1310. Online ahead of print.

Safety, tolerability, pharmacokinetic/pharmacodynamic characteristics of bersiporocin, a novel prolyl-tRNA synthetase inhibitor, in healthy subjects

Min Young Park, Sungyeun Bae, Jung A Heo, Mihee Park, YuKyung Kim, Jumi Han, In-Jin Jang, Kyung-Sang Yu, Jaeseong Oh

Clinical and translational science. 2023,Jul;16(7):1163-1176. doi: 10.1111/cts.13518. Epub 2023 Apr 24.

Comparison of the Pharmacokinetics, Safety, and Tolerability of Two Empagliflozin Formulations in Healthy Korean Subjects

Xu Jiang, Sungyeun Bae, Deok Yong Yoon, Shin Jung Park, Jaeseong Oh, Joo-Youn Cho, Kyung-Sang Yu

Drug design, development and therapy. 2023,Jul; 24;17:2137-2145. doi: 10.2147/DDDT.S409368. eCollection 2023.

Safety, Tolerability, and Pharmacokinetics of a Novel Macrocyclic Gadolinium-Based Contrast Agent, HNP-2006, in Healthy Subjects

Ki Young Huh, Woo Kyung Chung, Heejeong Lee, Seung Hong Choi, Kyung-Sang Yu, SeungHwan Lee

Investigative radiology. 2023,Jul;21. doi: 10.1097/RLI.0000000000001007. Online ahead of print.

Continuous versus intermittent infusion of human antithrombin III concentrate in the immediate postoperative period after liver transplantation

Bo Rim Kim, Leerang Lim, YoungRok Choi, Nam-Joon Yi, Kwang-Woong Lee 3, Kyung-Suk Suh 3, Kyung-Sang Yu, Jin Young Sohn, Raewon Jeong, Jaeseong Oh, Ho Geol Ryu

Clinical and translational science. 2023,Jul;16(7):1177-1185. doi: 10.1111/cts.13521. Epub 2023 Apr 24.

Exploring the Category and Use Cases on Digital Therapeutic Methodologies

Sunhee An, Jieun Ko, Kyung-Sang Yu, Hyuktae Kwon, Sungwan Kim, Jeeyoung Hong, Hyoun-Joong Kong

Healthcare informatics research. 2023,Jul;29(3):190-198. doi: 10.4258/hir.2023.29.3.190. Epub 2023 Jul 31.

Prediction of gastric pH-mediated drug exposure using physiologically-based pharmacokinetic modeling: A case study of itraconazole

Eunsol Yang, Kyung-Sang Yu, SeungHwan Lee

CPT: pharmacometrics & systems pharmacology. 2023,Jun;;12(6):865-877. doi: 10.1002/psp4.12959. Epub 2023 Mar 26.

Effect of haemodialysis on the pharmacokinetics and pharmacodynamics of evogliptin

Byungwook Kim, Dha Woon Im, Heejae Won, Jung Sunwoo, Seung Seok Han, Hajeong Lee, Dong Ki Kim, Kook-Hwan Oh, Kwon Wook Joo, Yon Su Kim, Joo-Youn Cho, SeungHwan Lee, Jaeseong Oh, In-Jin Jang, Yong Chul Kim

Diabetes, obesity and metabolism 2023,Jun;25(6):1769-1776. doi: 10.1111/dom.15034. Epub 2023 Apr 3.

Pharmacokinetics and safety of candidate tocilizumab biosimilar CT-P47 versus reference tocilizumab: a randomized, double-blind, single-dose phase I study

Kyung-Sang Yu, Byungwook Kim, Dongseong Shin, Min Kyu Park, Jun Gi Hwang, Min-Gul Kim, Hyewon Chung, JongLyul Ghim, Jae-Yong Chung, Josef S Smolen, Gerd R Burmester, SungHyun Kim, YunJu Bae, DaBee Jeon, JaeKyoung Yoo, GoEun Yang, JiHun Bae, Edward Keystone

Expert opinion on investigational drugs. 2023,May;;32(5):429-439. doi: 10.1080/13543784.2023.2212155. Epub 2023 May 26.

Pharmacokinetic and pharmacodynamic interaction of DWP16001, a sodium-glucose cotransporter 2 inhibitor, with gemigliptin and metformin in healthy adults

Sae Im Jeong, Yun Kim, Jae Jin Nah, Wan Huh, In-Jin Jang, Jun Gi Hwang, SeungHwan Lee

British journal of clinical pharmacology. 2023,Apr;89(4):1462-1470. doi: 10.1111/bcp.15613. Epub 2022 Dec 8.

Editorial: deja vu all over again - let the P-CAB wars begin. Authors' reply

Inyoung Hwang, SeungHwan Lee

Alimentary pharmacology & therapeutics. 2023,Apr;57(8):914-915. doi: 10.1111/apt.17444.

Safety, tolerability, pharmacokinetic/pharmacodynamic characteristics of bersiporocin, a novel prolyl-tRNA synthetase inhibitor, in healthy subjects

Min Young Park, Sungyeun Bae, Jung A Heo, Mihee Park, YuKyung Kim, Jumi Han, In-Jin Jang, Kyung-Sang Yu, Jaeseong Oh

Clinical and translational science. 2023,Apr;24. doi: 10.1111/cts.13518. Online ahead of print.

Pharmacokinetic and pharmacodynamic interaction between DWP16001, an sodium-glucose cotransporter 2 inhibitor and metformin in healthy subjects

Byungwook Kim, Ki Young Huh, Jun Gi Hwang, JaeJin Nah, Wan Huh, Jae Min Cho, In-Jin Jang, Kyung-Sang Yu, Yun Kim, SeungHwan Lee

British journal of clinical pharmacology. 2023,Apr;;89(4):1462-1470. doi: 10.1111/bcp.15613. Epub 2022 Dec 8.

Continuous versus intermittent infusion of human antithrombin III concentrate in the immediate postoperative period after liver transplantation

Bo Rim Kim, Leerang Lim, YoungRok Choi, Nam-Joon Yi, Kwang-Woong Lee, Kyung-Suk Suh, Kyung-Sang Yu, Jin Young Sohn, Raewon Jeong, Jaeseong Oh, Ho Geol Ryu

Clinical and translational science. 2023,Apr;10. doi: 10.1111/cts.13521. Online ahead of print.

A Comparison of the Pharmacokinetics and Safety of Dapagliflozin Formate, an Ester Prodrug of Dapagliflozin, to Dapagliflozin Propanediol Monohydrate in Healthy Subjects

Hyun Chul Kim, Sangmi Lee, Siyoung Sung, Eunjin Kim, In-Jin Jang, Jae-Yong Chung

Drug design, development and therapy. 2023,Apr; 21;17:1203-1210. doi: 10.2147/DDDT.S404182. eCollection 2023.

Pharmacokinetics and Pharmacodynamics of Esomezol DR, a New Dual Delayed-Release Formulation of Esomeprazole 20 Mg or 40 Mg, in Healthy Subjects

Hyun Chul Kim, Eunsol Yang, Mu Seong Ban, Yu Kyong Kim, Sung Hee Hong, Jina Jung, In-Jin Jang, SeungHwan Lee

Drug design, development and therapy. 2023,Apr;12;17:1115-1124. doi: 10.2147/DDDT.S392533. eCollection 2023.

Pharmacokinetics of dexmedetomidine in pediatric patients undergoing cardiac surgery with cardiopulmonary bypass

Eun-Hee Kim, Byung-Moon Choi, Pyoyoon Kang, Ji-Hyun Lee, Hee-Soo Kim, Young-Eun Jang, Sang-Hwan Ji, Gyu-Jeong Noh, Joo-Youn Cho, Jin-Tae Kim

Pediatric anesthesia 2023,Apr;33(4):303-311. doi: 10.1111/pan.14626. Epub 2023 Jan 16.

Conventional reversal of rocuronium-induced neuromuscular blockade by sugammadex in Korean children: pharmacokinetics, efficacy, and safety analyses

Sang-Hwan Ji, Ki Young Huh, Jaeseong Oh, Hee-Jeong Jeong, Young-Eun Jang, Eun-Hee Kim, Ji-Hyun Lee, Jin-Tae Kim, Hee-Soo Kim

Frontiers in pharmacology 2023,Apr;13;14:1127932. doi: 10.3389/fphar.2023.1127932. eCollection 2023.

Pharmacokinetics, safety and tolerability of valbenazine in Korean CYP2D6 normal and intermediate metabolizers

Woo Kyung Chung, Inyoung Hwang, Byungwook Kim, Jihyun Jung, Kyung-Sang Yu, In-Jin Jang, Jaeseong Oh

Clinical and translational science. 2023,Mar;16(3):512-523. doi: 10.1111/cts.13466. Epub 2022 Dec 27.

Evaluation of CYP2C19-Mediated Pharmacokinetic Drug Interaction of Tegoprazan, Compared with Vonoprazan or Esomeprazole

Eunsol Yang, Sang Chun Ji, In-Jin Jang, SeungHwan Lee

Clinical pharmacokinetics. 2023,Mar; 10. doi: 10.1007/s40262-023-01228-4. Online ahead of print.

Prediction of gastric pH-mediated drug exposure using physiologically-based pharmacokinetic modeling: A case study of itraconazole

Eunsol Yang, Kyung-Sang Yu, SeungHwan Lee

CPT: pharmacometrics & systems pharmacology. 2023,Mar;26. doi: 10.1002/psp4.12959. Online ahead of print.

Analysis of the distribution of trial sites in South Korea using social network analysis

Ki Young Huh, Kyung-Sang Yu, Ildae Song

Translational and clinical pharmacology. 2023,Mar;;31(1):1-12. doi: 10.12793/tcp.2023.31.e2. Epub 2023 Mar 22.

Baseline Tyrosine Level Is Associated with Dynamic Changes in FAST Score in NAFLD Patients under Lifestyle Modification

Hwi Young Kim, Da Jung Kim, Hye Ah Lee, Joo-Youn Cho, Won Kim

Metabolites 2023,Mar;17;13(3):444. doi: 10.3390/metabo13030444.

Randomised clinical trial: Safety, tolerability, pharmacodynamics and pharmacokinetics of zastaprazan (JP-1366), a novel potassium-competitive acid blocker, in healthy subjects

Inyoung Hwang, Sang Chun Ji, Jaeseong Oh, Hyojin Kim, Hyunju Cha, Jonhn Kim, Chang-Seok Lee, Kyug-Sang Yu, SeungHwan Lee

Alimentary pharmacology & therapeutics. 2023,Feb;2. doi: 10.1111/apt.17406. Online ahead of print.

Development of a Fast Onset Proton Pump Inhibitor: Comparison of Fixed-Dose Combination of Rabeprazole and Sodium Bicarbonate (YPI-011) to the Conventional Enteric-Coated Rabeprazole

Sungyeun Bae, Jihoon Kwon, Mi-Hye Lee, Kyung-Sang Yu, SeungHwan Lee

Drug design, development and therapy. 2023,Feb;15;17:497-506. doi: 10.2147/DDDT.S391716. eCollection 2023.

Pharmacodynamic and Pharmacokinetic Drug Interactions between Fexuprazan, a Novel Potassium-Competitive Inhibitor, and Aspirin, in Healthy Subjects

JungJin Oh, Eunsol Yang, In-Jin Jang, Hyejung Lee, Hokyun Yoo, Jae-Yong Chung, SeungHwan Lee, Jaeseong Oh

Pharmaceutics. 2023,Feb; 7;15(2):549. doi: 10.3390/pharmaceutics15020549.

Targeted Metabolomic Biomarkers for Stroke Subtyping

Eung-Joon Lee, Da Jung Kim, Dong-Wan Kang, Wookjin Yang, Han-Yeong Jeong, Jeong-Min Kim, Sang-Bae Ko, Seung-Hoon Lee, Byung-Woo Yoon, Joo-Youn Cho, Keun-Hwa Jung

Translational stroke research. 2023,Feb;11. doi: 10.1007/s12975-023-01137-5. Online ahead of print.

Dynamic changes in clinical biomarkers of cardiometabolic diseases by changes in exercise behavior, and network comparisons: a community-based prospective cohort study in Korea

JooYong Park, Jaesung Choi, Ji-Eun Kim, Sang-Min Park, Joo-Youn Cho, Daehee Kang, Miyoung Lee, Ji-Yeob Choi

Epidemiology and health. 2023,Feb;;45:e2023026. doi: 10.4178/epih.e2023026. Epub 2023 Feb 16.

Effects of food and race on the pharmacokinetics of lazertinib in healthy subjects and patients with EGFR mutation-positive advanced non-small cell lung cancer

Ki Young Huh, Yeji Lim, Deok Yong Yoon, Jun Gi Hwang, Sujin Sim, Jiah Kang, Jangyoung Wang, Mikyung Kim, Seong Bok Jang, S Martin Shreeve, Jaydeep Mehta, Nahor Haddish-Berhane, Jaeseong Oh, SeungHwan Lee, Kyung-Sang Yu

LUNG CANCER 2023,Jan;;175:112-120. doi: 10.1016/j.lungcan.2022.11.021. Epub 2022 Dec 2.

Evaluation of Safety, Tolerability and Pharmacokinetic Characteristics of SA001 and Its Active Metabolite Rebamipide after Single and Multiple Oral Administration

Sungyeun Bae, Ki Young Huh, Jaeseong Oh, Kyung-Sang Yu, Anhye Kim

Pharmaceuticals. 2023,Jan;16;16(1):132. doi: 10.3390/ph16010132.

Comparison of Pharmacodynamics between Tegoprazan and Dexlansoprazole Regarding Nocturnal Acid Breakthrough: A Randomized Crossover Study. Gut Liver.

Sungpil Han, Hee Youn Choi, Yo Han Kim, SeungChan Choi, Seokuee Kim, Ji Yeon Nam, Bongtae Kim, Geun Seog Song, Hyeong-Seok Lim, Kyun-Seop Bae

Gut and liver 2023,Jan;15;17(1):92-99. doi: 10.5009/gnl220050. Epub 2022 Nov 1.

Reversal of rocuronium-induced intense neuromuscular blockade by sugammadex in Korean children: A pharmacokinetic and pharmacodynamic analysis

Sang-Hwan Ji, Ki Young Huh, Jaeseong Oh, Hee-Jeong Jeong, Young-Eun Jang, Eun-Hee Kim, Ji-Hyun Lee, Jin-Tae Kim, Hee-Soo Kim

Clinical and translational science. 2023,Jan;16(1):92-103. doi: 10.1111/cts.13429. Epub 2022 Oct 17.

Protective role of colitis in inflammatory arthritis via propionate-producing Bacteroides in the gut

Hoh-Jeong Shon, Yu-Mi Kim, Kyeong Seog Kim, Jin-Ouk Choi, Sang-Hyun Cho, Sujin An, Se-Hyeon Park, Yong-Joon Cho, Joo-Hong Park, Sang-Uk Seo, Joo-Youn Cho, Wan-Uk Kim, Donghyun Kim

Frontiers in immunology. 2023,Jan; 30;14:1064900. doi: 10.3389/fimmu.2023.1064900. eCollection 2023.