SNUCPT

Effect of Narrowband Ultraviolet B Phototherapy on Systemic Metabolome in Korean Patients With Psoriasis

Yufei Li, Yujin Lee, Howard Lee, Seong-Jin Jo, Joo-Youn Cho

Exp Dermatol 2024,Oct;2024 Oct;33(10):e15192. doi: 10.1111/exd.15192.

Population pharmacokinetic model of ABL001/CTX-009 (anti-VEGF/DLL4) in adult cancer patients with solid tumor

Joo Young Na, Juyeun Jeon, Ki Young Huh, Kyung-Sang Yu, Sangmi Lee, Jaehyun Eom, Jinhyung Ahn, Weon-Kyoo You, Jaeseong Oh

Cancer Sci 2024,Oct;2024 Oct 7. doi: 10.1111/cas.16363. Online ahead of print.

Population pharmacokinetic analysis of zastaprazan (JP-1366), a novel potassium-competitive acid blocker, in patients and healthy volunteers

Eunsol Yang, Inyoung Hwang, Sang Chun Ji, John Kim, SeungHwan Lee

CPT Pharmacometrics Syst Pharmacol 2024,Sep;2024 Sep 13. doi: 10.1002/psp4.13228. Online ahead of print.

A randomized study to evaluate the safety and immunogenicity of a pentavalent meningococcal vaccine

Yoonjin Kim, Sungyeun Bae, Kyung-Sang Yu, SeungHwan Lee, Chankyu Lee, Jinil Kim, Howard Her, Jaeseong Oh

NPJ Vaccines 2024,Aug;9(1):140. doi: 10.1038/s41541-024-00935-8.

Metabolic profiling of psoriasis vulgaris and palmoplantar pustulosis

Yujin Lee, Seong Rae Kim, Mu Seong Ban, Howard Lee, Joo-Youn Cho, Seong Jin Jo

Exp Dermatol 2024,Aug;2024 Aug;33(8):e15159. doi: 10.1111/exd.15159.

Nasal symbiont Staphylococcus epidermidis restricts influenza A virus replication via the creation of a polyamine-deficient cellular environment

Ara Jo, Kyeong-Seog Kim, Jina Won, Haeun Shin, Sujin Kim, Bora Kim, Da Jung Kim, Joo-Youn Cho, Hyun Jik Kim

Commun Biol 2024,Aug;2024 Aug 22;7(1):1031. doi: 10.1038/s42003-024-06706-4.

Coadministration of Voriconazole and Rifabutin Can Increase the Risk of Adverse Drug Reactions in Patients with Multiple Infections

Yoonjin Kim, Sungyeun Bae, Ki Young Huh, Jong Sun Joo, Jikyo Lee, Sang Hoon Song, Kyung-Sang Yu, In-Jin Jang, Jaeseong Oh

Ther Drug Monit 2024,Jul; doi: 10.1097/FTD.0000000000001241. Online ahead of print.

Pharmacokinetics and safety of candidate tocilizumab biosimilar CT-P47 administered by auto-injector or pre-filled syringe: a randomized, open‑label, single-dose phase I study

Kyung-Sang Yu, Hyunwook Ryu, Dongseong Shin, MinKyu Park, JunGi Hwang, Seol Ju Moon, Min-Gul Kim, Edward Keystone, Josef S Smolen, SungHyun Kim, YunJu Bae, DaBee Jeon, JiYoung Jang, GoEun Yang, JiHun Bae, JaeYong Lee, Gerd R Burmester

Expert Opin Biol Ther 2024,Jul;24(7):681-689. doi: 10.1080/14712598.2024.2321360. Epub 2024 Jun 21.

The effect of renal function on the pharmacokinetics and pharmacodynamics of enavogliflozin, a potent and selective sodium-glucose cotransporter-2 inhibitor, in type 2 diabetes

Sae Im Jeong, Mu Seong Ban, Jun-Gi Hwang, Min-Kyu Park, Soo Lim, Sejoong Kim, Soon Kil Kwon, Yoonjin Kim, Jae Min Cho, Jae Jin Na, Wan Huh, Jae-Yong Chung

Diabetes Obes Metab 2024,Jul;26(7):2588-2597. doi: 10.1111/dom.15573. Epub 2024 Apr 15.

Pharmacokinetic interactions between fexuprazan, a potassium-competitive acid blocker, and nonsteroidal anti-inflammatory drugs in healthy males

Heejae Won, Eunwoo Kim, Jihye Chae, Hyejung Lee, Joo-Youn Cho, In-Jin Jang, Jae-Yong Chung, Min-Gul Kim, SeungHwan Lee

Clin Transl Sci 2024,May;17(5):e13798. doi: 10.1111/cts.13798.

Pioglitazone-induced alterations of purine metabolism in healthy male subjects

Jihyun Kang, Yufei Li, SeungHwan Lee, Kyung-Sang Yu, Joo-Youn Cho

Clin Transl Sci 2024,May;17(5):e13834. doi: 10.1111/cts.13834

Targeted Metabolomic Biomarkers for Stroke Subtyping

Eung-Joon Lee, Da Jung Kim, Dong-Wan Kang, Wookjin Yang, Han-Yeong Jeong, Jeong-Min Kim, Sang-Bae Ko, Seung-Hoon Lee, Byung-Woo Yoon, Joo-Youn Cho, Keun-Hwa Jung

Translational stroke research. 2024,Apr;15(2):422-432. doi: 10.1007/s12975-023-01137-5. Epub 2023 Feb 11.

Pharmacokinetics, pharmacodynamics and safety of oral formulation (CG-750) of ivaltinostat, a histone deacetylase inhibitor, compared to IV formulation (CG-745)

Byungwook Kim, Ki Young Huh, Kyung-Sang Yu, SeungHwan Lee

British journal of clinical pharmacology. 2024,Apr;90(4):1103-1114. doi: 10.1111/bcp.15997. Epub 2024 Jan 23.

A Population Pharmacokinetic Study to Compare a Novel Empagliflozin L-Proline Formulation with Its Conventional Formulation in Healthy Subjects

Xu Jiang, Kyung-Sang Yu, Dong Hyuk Nam, Jaeseong Oh

Pharmaceuticals (Basel) 2024,Apr;17(4):522. doi: 10.3390/ph17040522.

Safety, Tolerability, and Pharmacokinetics of a Novel Macrocyclic Gadolinium-Based Contrast Agent, HNP-2006, in Healthy Subjects

Ki Young Huh, Woo Kyung Chung, Heejeong Lee, Seung Hong Choi, Kyung-Sang Yu, SeungHwan Lee

Investigative radiology. 2024,Mar;1;59(3):252-258.

Synergistic toxicity with copper contributes to NAT2-associated isoniazid toxicity

Jihoon G Yoon, Dong Geon Jang, Sung-Gyu Cho, Chaeyoung Lee, Shin Hye Noh, Soo Kyung Seo, Jung Woo Yu, Hyeon Woo Chung 3, KyeoRe Han, Soon Sung Kwon, Dai Hoon Han, Jaeseong Oh, In-Jin Jang, Sang-Hoon Kim, Young-Koo Jee, Hyun Lee, Dong Won Park, Jang Won S

Experimental & molecular medicine. 2024,Mar;1. doi: 10.1038/s12276-024-01172-8. Online ahead of print.

Profiling of endogenous metabolites and changes in intestinal microbiota distribution after GEN-001 ( Lactococcus lactis) administration

Min-Gul Kim, Suin Kim, Ji-Young Jeon, Seol Ju Moon, Yong-Geun Kwak 1 3, Joo Young Na 5, SeungHwan Lee, Kyung-Mi Park, Hyo-Jin Kim, Sang-Min Lee, Seo-Yeon Choi, Kwang-Hee Shin

Korean J Physiol Pharmacol. 2024,Mar; 1;28(2):153-164. doi: 10.4196/kjpp.2024.28.2.153.

Effects of meal type on the bioavailability of vutiglabridin, a novel anti-obesity agent, in healthy subjects

Heejae Won, Deok Yong Yoon, Sangmi Lee, Joo-Youn Cho, Jaeseong Oh, In-Jin Jang, Sang-Ku Yoo, Kyung-Sang Yu

Clin Transl Sci 2024,Mar;17(3):e13744. doi: 10.1111/cts.13744.

Estimation of the benefit from pre-emptive genotyping based on the nationwide cohort data in South Korea

Ki Young Huh, Sejung Hwang, Joo Young Na, Kyung-Sang Yu, In-Jin Jang, Jae-Yong Chung, Seonghae Yoon

Clin Transl Sci 2024,Mar;17(3):e13772. doi: 10.1111/cts.13772.

Establishment of Advanced Regulatory Innovation for Clinical Trials Transformation (ARICTT): a multi-stakeholder public-private partnership-based organization to accelerate the transformation of clinical trials

Woo Kyung Chung, Ki Young Huh, Jiyeon Park, Jaeseong Oh, Kyung-Sang Yu

Transl Clin Pharmacol 2024,Mar;32(1):30-40. doi: 10.12793/tcp.2024.32.e1. Epub 2024 Feb 20.

The landscape of decentralized clinical trials (DCTs): focusing on the FDA and EMA guidance

Jiyeon Park, Ki Young Huh, Woo Kyung Chung, Kyung-Sang Yu

Transl Clin Pharmacol 2024,Mar;32(1):41-51. doi: 10.12793/tcp.2024.32.e2. Epub 2024 Feb 20.

Topiramate dosage optimization for effective antiseizure management via population pharmacokinetic modeling

Seolah Lee, Hyun Chul Kim, Yoonhyuk Jang, Han Sang Lee, Seon-Jae Ahn, Soon-Tae Lee, Keun-Hwa Jung, Kyung-Il Park, Ki-Young Jung, Jaeseong Oh, SeungHwan Lee, Kyung-Sang Yu, In-Jin Jang, Soyoung Lee, Kon Chu, Sang Kun Lee

Annals of clinical and translational neurology. 2024,Feb;11(2):424-435. doi: 10.1002/acn3.51962. Epub 2023 Dec 7.

Evaluation of Food Effect on the Pharmacokinetics of Velufenacin, a New Muscarinic Receptor Antagonist, in Healthy Subjects

Juyoung Khwarg, Woo Kyung Chung, Soyoung Lee, Eunsol Yang, Chaelim Ryu, Dae Young Lee, Min Jung Lee, In-Jin Jang, Kyung-Sang Yu, SeungHwan Lee

Clinical pharmacology in drug development. 2024,Feb;13(2):128-133. doi: 10.1002/cpdd.1361. Epub 2023 Dec 29.

Effects of food and ethnicity on the pharmacokinetics of venadaparib, a next-generation PARP inhibitor, in healthy Korean, Caucasian, and Chinese male subjects

Hyun Chul Kim, Eunsol Yang, Soyoung Lee, Jaeseong Oh, Myongjae Lee, ChaeEun Lee, Kyoung Soo Ha, Won Sik Lee, In-Jin Jang, Kyung-Sang Yu

Investigational new drugs. 2024,Feb;42(1):80-88. doi: 10.1007/s10637-023-01405-z. Epub 2023 Dec 15.

Pharmacokinetic Comparison Between a Fixed-Dose Combination of Atorvastatin/Omega-3-Acid Ethyl Esters and the Corresponding Loose Combination in Healthy Korean Male Subjects

Juyoung Khwarg, Soyoung Lee, In-Jin Jang, Won-Ho Kang, Hye Jung Lee, Kyu Yeon Kim, Ki-Sun Jeong, Chongho Won, Youn Woong Choi 5, Dae Chul Ha 5, RaeHoon Jung 5, Min-Gu Han, Won Tae Jung, Kyu-Yeol Nam, YeSeul Kim, Kyung-Sang Yu, Jaeseong Oh

Drug design, development and therapy. 2024,Feb;8:18:395-406.

Pharmacogenetic Analysis of an 8-Year Old Girl with Reye Syndrome Associated with Use of Naproxen

Byungwook Kim, Joo-Youn Cho, Ildae Song, Jaeseong Oh

The American journal of case reports. 2024,Feb;5:25:e942242. doi: 10.12659/AJCR.942242.

Differences in Brain Metabolite Profiles Between Normothermia and Hypothermia

Suk Ho Sohn, Sihyun Chae, Jae Woong Choi, Karam Nam, Youn Joung Cho, Joo-Youn Cho, Ho Young Hwang

Journal of Korean medical science. 2024,Feb;26;39(7):e79. doi: 10.3346/jkms.2024.39.e79.

Metabolomic Characteristics of Nontuberculous Mycobacterial Pulmonary Disease

Jungeun Kim, Woori Chae, Joong-Yub Kim, Jae-Joon Yim, Joo-Youn Cho, Nakwon Kwak

J Infect Dis 2024,Feb;doi: 10.1093/infdis/jiae100. Online ahead of print.

A 6-month exercise intervention clinical trial in women: effects of physical activity on multi-omics biomarkers and health during the first wave of COVID-19 in Korea

JooYong Park, Jaemyung Kim, Jihyun Kang, Jaesung Choi, Ji-Eun Kim, Kyung-Joon Min, Seong-Woo Choi, Joo-Youn Cho, Miyoung Lee, Ji-Yeob Choi

BMC sports science, medicine and rehabilitation 2024,Jan;29;16(1):30. doi: 10.1186/s13102-024-00824-6.