RESEARCH

https://cpt.snu.ac.kr/en/Research/Achievment/NewDrugDevelopment URL COPY

Department of Clinical Pharmacology and Therapeutics of Seoul National University college of Medicine and Hospital contributes to successful clinical development of new drugs through conducting clinical trials and consultation of clinical trials development.

  • 2015

    SUGANON – Dong-A ST Co.,LtdOral Hypoglycemic Agent

  • 2012

    ZEMIGLO - LG Life Sciences, LtdAntidiabetics

  • 2010

    KANARB - Boryung Pharmaceutical Co., Ltd.Antihypertensive agents

※ Click on the product above
to see the relevant clinical trial details.

연구성과
Approved year Product name Active ingredient Efficacy Company
2018 K-CAB Tablet Tegoprazan Antiulcer CJ HealthCare Co.
2015 SUGANON Evogliptin tartrate Oral hypoglycemic agent Dong-A ST Co.,Ltd
2015 Sivextro Injection Tedizolid phosphate Antibiotics Dong-A ST Co.,Ltd
2013 DUVIE Tablet Lobeglitazone sulfate Antidiabetics Chong Kun Dang Pharmaceutical Corp.
2012 Gemigliptin Tablet Gemigliptn Tartrate Sesquihydrate, Metformin Hydrocholoride Antidiabetics LG Chem, Ltd
2011 PYRAMAX Pyronaridone, Altesunate Antimalarial agent Shinpoong Pharm.co.,LTd
2010 Kanarb Tablet Fimasartan Potassium Trihydrate Antihypertensive agents Boryung Pharmaceutical Co.,Ltd.
2007 MVIX TAB. Mirodenafil Erectile dysfunction agent SK Discovery Co.
2005 ZYDENA Tablet Undenafil Erectile dysfunction agent Dong-A ST Co.,Ltd
2005 REVANEX Revaprazan Antiulcer Yuhan Corporation
2002 Factive Tablet Gemigliptn Tartrate Sesquihydrate Antibiotics LG Chem, Ltd
2001 Q-ROXIN TAB. Balofloxacin Antibiotics JW Pharmaceutical
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2015년

슈가논정 - 동아에스티(주)
경구용 혈당 강하제

신약 임상개발 성공사례 - 슈가논정
연번 임상시험 제목 수행년도 NCT번호
1 A Study to Characterize the Pharmacokinetics/Pharmacodynamics and Effect of Food of DA-1229 in Healthy Male Subjects 2009 NCT00961025
2 Pharmacokinetic/Pharmacodynamic Drug-drug Interaction of DA-1229 and Metformin After Oral Administration in Healthy Male Subjects 2013 NCT01941199
3 PK/PD/Tolerability Study of DA-1229(Evogliptin) in Renal Impaired Patients 2014 NCT02214693
4 A Clinical Trial to Investigate Safety/Tolerability and Pharmacokinetics of DA-1229_01 Compared to Co-administration of Evogliptin 5 mg and Metformin XR 1000 mg, and to Evaluate the Effect of Food on the Pharmacokinetics of DA-1229_01 in Healthy Male Volunteers 2014 NCT02167061
5 A Clinical Trial to Investigate Safety/Tolerability and Pharmacokinetics of DA-1229_01(Evogliptin/Metformin XR 2.5/500 mg x 2 Tablets) Compared to Co-administration of Evogliptin 5 mg and Metformin XR 1000 mg in Healthy Male Volunteers 2015 NCT02375139
6 Pharmacokinetic/Pharmacodynamic Drug-drug Interaction of Evogliptin 5 mg and Pioglitazone 30 mg 2016 NCT02753803
7 Pharmacokinetic/Pharmacodynamic Drug-drug Interaction of Evogliptin 5mg and Glimepiride 4mg 2016 NCT02954822

2012년

제미글로정 - ㈜LG생명과학
당뇨병 치료제

연번 임상시험 제목 수행년도 NCT번호
1 A dose block-randomized, double-blind, placebo-controlled, single/multiple dosing, dose-escalation clinical phase 1 trial to investigate the safety, tolerability, and pharmacokinetics/pharmacodynamics of LC15-0444 Tartrate after oral administration in healthy male subjects 2006
2 Pharmacokinetic Drug Interaction Between LC15-0444 and Pioglitazone After Oral Administration in Healthy Male Subjects 2009 NCT01001013
3 Pharmacokinetic/Pharmacodynamic Drug-drug Interaction of LC15-0444 and Metformin After Oral Administration in Healthy Male Subjects 2011 NCT01426399
4 BE Study of the Combinations of Gemigliptin 50mg and Metformin HCl Extended Release 500mg in Comparison to Each Component Administered Alone 2012 NCT01595880
5 BE Study of the Combinations of Gemigliptin 50mg and Metformin HCl Extended Release 1000mg in Comparison to Each Component Administered Alone 2012 NCT01662674
6 BE Study of the Combinations of Gemigliptin 50mg and Rosuvastatin 20mg in Comparison to Each Component Administered Alone 2015 NCT02670070

2011년

카나브정-보령제약(주)
고혈압치료제

연번 임상시험 제목 수행년도 NCT번호
1 A Study to Evaluate the Effect of Atorvastatin on the Pharmacokinetics of Fimasartan in Healthy Male Volunteers 2009 NCT00991705
2 A Study to Evaluate the Effect of Fimasartan on Pharmacokinetics, and the Safety of Digoxin in Healthy Male Volunteers 2009 NCT00991783
3 A Study to Evaluate the Pharmacokinetic Drug Interaction After Oral Concurrent Administration of Fimasartan and Amlodipine in Healthy Male Volunteers 2009 NCT00938197
4 A Study to Evaluate the Safety and Pharmacokinetics After Oral Concurrent Administration of Fimasartan and Hydrochlorothiazide in Healthy Male Volunteers 2009 NCT00923533
5 A Study to Evaluate the Effect of Ketoconazole and Rifampicin on the Pharmacokinetics of Fimasartan in Healthy Male Volunteers 2009 NCT00938262
6 A Clinical Trial to Evaluate the Effect of Fimarsartan on Pharmacodynamics, Pharmacokinetics, and the Safety of Warfarin in Healthy Male Volunteers 2009 NCT00938132
7 A Clinical Trial to Compare and Evaluate the Pharmacokinetic Characteristics and the Safety of Fimasartan in Renal Impairment Patients and Healthy Volunteers 2010 NCT01148368
8 A Clinical Trial to Evaluate Efficacy, Tolerability, and Pharmacokinetic-Pharmacodynamic Relationship of Fimasartan/Hydrochlorothiazide 2014 NCT02222480
9 Study to Evaluate the Pharmacokinetic Interaction Between Fimasartan and Atorvastatin in Healthy Male Volunteers 2015 NCT02397590
10 A Clinical Trial to Evaluate the Pharmacokinetics and Safety of Fimasartan and Amlodipine in Healthy Male Subjects 2016 NCT02920047
11 A Clinical Trial to Evaluate the Pharmacokinetics and Safety/Tolerability of Fimasartan and Atorvastatin in Healthy Male Volunteers 2016 NCT02994745