A parallel reaction monitoring-mass spectrometric method for studying lipid biosynthesis in vitro using 13C16-palmitate as an isotope tracer

Kyeong-Seog Kim, Young Gyun Ko, Woo Seok Yang, Hye Young Kim, Joo-Youn Cho

Anal Chim Acta 2025,Jun;1354:344003. doi: 10.1016/j.aca.2025.344003. Epub 2025 Apr 1.

Accurate Determination of Circulatory Lipids Using a Combination of HILIC-MRM and RPLC-PRM

Kyeong-Seog Kim, Jae-Seung Lee, Seung Seok Han, Joo-Youn Cho

Anal Chem 2025,May;doi: 10.1021/acs.analchem.4c06409. Online ahead of print.

Coadministration of Voriconazole and Rifabutin Can Increase the Risk of Adverse Drug Reactions in Patients with Multiple Infections

Yoonjin Kim, Sungyeun Bae, Ki Young Huh, Jong Sun Joo, Jikyo Lee, Sang Hoon Song, Kyung-Sang Yu, In-Jin Jang, Jaeseong Oh

Ther Drug Monit 2025,Apr;47(2):303-308. doi: 10.1097/FTD.0000000000001241. Epub 2024 Jul 16.

Modulating the PD-1-FABP5 axis in ILC2s to regulate adipose tissue metabolism in obesity

Jongho Ham, Jaemoon Koh, Jungeun Kim, Joo-Youn Cho, TaeSoo Kim, Doo Hyun Chung, Yong-Soo Bae, Hye Young Kim

Mol Ther 2025,Apr;33(4):1842-1859. doi: 10.1016/j.ymthe.2025.02.015. Epub 2025 Feb 12.

Evaluation of Safety, Pharmacokinetic, and Pharmacodynamic Characteristics of a Novel Dual mGluR5/5‑HT2AR Antagonist (VVZ‑2471) in a Randomized, Double‑Blind, First‑in‑Human Study

Sungyeun Bae, HyunJoon Lee, Inkyung Song, Jina Kim, Sang Rim Lee, Sunyoung Cho, Kyung-Sang Yu, Jae-Yong Chung

CNS Drugs 2025,Apr;doi: 10.1007/s40263-025-01181-9. Online ahead of print.

Comparative pharmacokinetics and bioequivalence of 145-mg fenofibrate formulations in healthy Korean participants

Sujong Lee, Byungwook Kim, SeungHwan Lee, Seung-Hyun Kang, Kyung-Sang Yu

Naunyn Schmiedebergs Arch Pharmacol 2025,Apr;doi: 10.1007/s00210-025-04086-y. Online ahead of print.

Short-term efficacy and safety of metformin in individuals with type 2 diabetes and mild hepatic impairment: A propensity score-matched real-world study

Seunghwan Baek, Jongseok Park, Jae-Yong Chung, Soo Heon Kwak, Seonghae Yoon

Diabetes Obes Metab 2025,Mar;32(3):150-158. doi: 10.12793/tcp.2024.32.e14. Epub 2024 Sep 25.

Exploration of Using an Open-Source Large Language Model for Analyzing Trial Information: A Case Study of Clinical Trials With Decentralized Elements

Ki Young Huh, Ildae Song, Yoonjin Kim, Jiyeon Park, Hyunwook Ryu, JaeEun Koh, Kyung-Sang Yu, Kyung Hwan Kim, SeungHwan Lee

Clin Transl Sci 2025,Mar;18(3):e70183. doi: 10.1111/cts.70183.

Pharmacokinetics of post-transplant cyclophosphamide and its associations with clinical outcomes in pediatric haploidentical hematopoietic stem cell transplantation

Kyung Taek Hong, Sungyeun Bae, Yoon Sunwoo, Juyeon Lee, Hyun Jin Park, Bo Kyung Kim, Jung Yoon Choi, Joo-Youn Cho, Kyung-Sang Yu, Jaeseong Oh, Hyoung Jin Kang

Biomark Res 2025,Mar;13(1):48. doi: 10.1186/s40364-025-00749-3.

Clinical development of oral semaglutide for the treatment of type 2 diabetes mellitus: focusing on early phase clinical trials

Heejae Won, Joo-Youn Cho, SeungHwan Lee

Transl Clin Pharmacol 2025,Mar;33(1):1-9. doi: 10.12793/tcp.2025.33.e3. Epub 2025 Mar 20.

Comparison of pharmacokinetics of a fixed-dose combination of atorvastatin/ezetimibe 5 mg/10 mg versus separate tablets in healthy subjects

Jisoo Song, Sungyeun Bae, Kyung-Sang Yu, SeungHwan Lee

Transl Clin Pharmacol 2025,Mar;33(1):40-49. doi: 10.12793/tcp.2025.33.e5. Epub 2025 Mar 24.

Population pharmacokinetic and pharmacodynamic model of evogliptin: Severe uremia increases the bioavailability of evogliptin

Byungwook Kim, Jung Eun Kim, Soyoung Lee, Jaeseong Oh, Joo-Youn Cho, In-Jin Jang, SeungHwan Lee, Jae-Yong Chung, Seonghae Yoon

CPT Pharmacometrics Syst Pharmacol 2025,Feb;doi: 10.1002/psp4.13263. Online ahead of print.

Pharmacokinetic comparison of a fixed-dose combination of telmisartan/rosuvastatin/ezetimibe/amlodipine 80/20/10/5 mg and a loose-dose combination of ezetimibe/rosuvastatin 10/20 mg and telmisartan/amlodipine 80/5 mg in healthy male subjects

Sooyoun Lee, Hyun Chul Kim, Kyung Tae Kim, Seung-Hyun Kang, SeungHwan Lee, Kyung-Sang Yu, Soyoung Lee

Naunyn Schmiedebergs Arch Pharmacol 2025,Feb;doi: 10.1007/s00210-025-03863-z. Online ahead of print.

Phase 1 studies of the safety, tolerability, pharmacokinetics, and pharmacodynamics of BI 690517 (vicadrostat), a novel aldosterone synthase inhibitor, in healthy male volunteers

Friedrich Schulze, Jennifer Schaible, Markus Goettel, Yuko Tanaka, Kathrin Hohl, Armin Schultz, In-Jin Jang

Naunyn Schmiedebergs Arch Pharmacol 2025,Feb;doi: 10.1007/s00210-025-03838-0. Online ahead of print.

Clustering-Based Identification of BMI-Associated Metabolites with Mechanistic Insights from Network Analysis in Korean Men

JooYong Park, Jihyun Kang, Ji-Yeoun Lee, Daehee Kang, Joo-Youn Cho, Ji-Yeob Choi

Metabolites 2025,Feb;15(2):88. doi: 10.3390/metabo15020088.

Comparing haploidentical transplantation with post-transplantation cyclophosphamide and umbilical cord blood transplantation using targeted busulfan in children and adolescents with hematologic malignancies

Kyung Taek Hong, Bo Kyung Kim, Hong Yul An, Jung Yoon Choi, Sang Hoon Song, Kyung-Sang Yu, In-Jin Jang, Hyoung Jin Kang

Blood Res 2025,Jan;60(1):7. doi: 10.1007/s44313-025-00057-7.

Comparing the efficacy of different proton pump inhibitor dosing regimens for the treatment of gastroesophageal reflux disease: a systematic review and meta-analysis

Tyra Nguyen, Katherine Barnhill, Alex Zhornitskiy, Kyung Sang Yu, Garth Fuller, Katherine Makaroff, Brennan M R Spiegel, Gillian Gresham, Christopher V Almario

Dis Esophagus 2025,Jan;38(1):doae109. doi: 10.1093/dote/doae109.