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01

Effect of Narrowband Ultraviolet B Phototherapy on Systemic Metabolome in Korean Patients With Psoriasis

Yufei Li, Yujin Lee, Howard Lee, Seong-Jin Jo, Joo-Youn Cho

Exp Dermatol 2024,Oct;2024 Oct;33(10):e15192. doi: 10.1111/exd.15192.
02

Population pharmacokinetic model of ABL001/CTX-009 (anti-VEGF/DLL4) in adult cancer patients with solid tumor

Joo Young Na, Juyeun Jeon, Ki Young Huh, Kyung-Sang Yu, Sangmi Lee, Jaehyun Eom, Jinhyung Ahn, Weon-Kyoo You, Jaeseong Oh

Cancer Sci 2024,Oct;2024 Oct 7. doi: 10.1111/cas.16363. Online ahead of print.
03

Population pharmacokinetic analysis of zastaprazan (JP-1366), a novel potassium-competitive acid blocker, in patients and healthy volunteers

Eunsol Yang, Inyoung Hwang, Sang Chun Ji, John Kim, SeungHwan Lee

CPT Pharmacometrics Syst Pharmacol 2024,Sep;2024 Sep 13. doi: 10.1002/psp4.13228. Online ahead of print.
04

A randomized study to evaluate the safety and immunogenicity of a pentavalent meningococcal vaccine

Yoonjin Kim, Sungyeun Bae, Kyung-Sang Yu, SeungHwan Lee, Chankyu Lee, Jinil Kim, Howard Her, Jaeseong Oh

NPJ Vaccines 2024,Aug;9(1):140. doi: 10.1038/s41541-024-00935-8.
05

Metabolic profiling of psoriasis vulgaris and palmoplantar pustulosis

Yujin Lee, Seong Rae Kim, Mu Seong Ban, Howard Lee, Joo-Youn Cho, Seong Jin Jo

Exp Dermatol 2024,Aug;2024 Aug;33(8):e15159. doi: 10.1111/exd.15159.
06

Nasal symbiont Staphylococcus epidermidis restricts influenza A virus replication via the creation of a polyamine-deficient cellular environment

Ara Jo, Kyeong-Seog Kim, Jina Won, Haeun Shin, Sujin Kim, Bora Kim, Da Jung Kim, Joo-Youn Cho, Hyun Jik Kim

Commun Biol 2024,Aug;2024 Aug 22;7(1):1031. doi: 10.1038/s42003-024-06706-4.
07

Coadministration of Voriconazole and Rifabutin Can Increase the Risk of Adverse Drug Reactions in Patients with Multiple Infections

Yoonjin Kim, Sungyeun Bae, Ki Young Huh, Jong Sun Joo, Jikyo Lee, Sang Hoon Song, Kyung-Sang Yu, In-Jin Jang, Jaeseong Oh

Ther Drug Monit 2024,Jul; doi: 10.1097/FTD.0000000000001241. Online ahead of print.
08

Pharmacokinetics and safety of candidate tocilizumab biosimilar CT-P47 administered by auto-injector or pre-filled syringe: a randomized, open‑label, single-dose phase I study

Kyung-Sang Yu, Hyunwook Ryu, Dongseong Shin, MinKyu Park, JunGi Hwang, Seol Ju Moon, Min-Gul Kim, Edward Keystone, Josef S Smolen, SungHyun Kim, YunJu Bae, DaBee Jeon, JiYoung Jang, GoEun Yang, JiHun Bae, JaeYong Lee, Gerd R Burmester

Expert Opin Biol Ther 2024,Jul;24(7):681-689. doi: 10.1080/14712598.2024.2321360. Epub 2024 Jun 21.
09

The effect of renal function on the pharmacokinetics and pharmacodynamics of enavogliflozin, a potent and selective sodium-glucose cotransporter-2 inhibitor, in type 2 diabetes

Sae Im Jeong, Mu Seong Ban, Jun-Gi Hwang, Min-Kyu Park, Soo Lim, Sejoong Kim, Soon Kil Kwon, Yoonjin Kim, Jae Min Cho, Jae Jin Na, Wan Huh, Jae-Yong Chung

Diabetes Obes Metab 2024,Jul;26(7):2588-2597. doi: 10.1111/dom.15573. Epub 2024 Apr 15.
10

Pharmacokinetic interactions between fexuprazan, a potassium-competitive acid blocker, and nonsteroidal anti-inflammatory drugs in healthy males

Heejae Won, Eunwoo Kim, Jihye Chae, Hyejung Lee, Joo-Youn Cho, In-Jin Jang, Jae-Yong Chung, Min-Gul Kim, SeungHwan Lee

Clin Transl Sci 2024,May;17(5):e13798. doi: 10.1111/cts.13798.
11

Pioglitazone-induced alterations of purine metabolism in healthy male subjects

Jihyun Kang, Yufei Li, SeungHwan Lee, Kyung-Sang Yu, Joo-Youn Cho

Clin Transl Sci 2024,May;17(5):e13834. doi: 10.1111/cts.13834
12

Targeted Metabolomic Biomarkers for Stroke Subtyping

Eung-Joon Lee, Da Jung Kim, Dong-Wan Kang, Wookjin Yang, Han-Yeong Jeong, Jeong-Min Kim, Sang-Bae Ko, Seung-Hoon Lee, Byung-Woo Yoon, Joo-Youn Cho, Keun-Hwa Jung

Translational stroke research. 2024,Apr;15(2):422-432. doi: 10.1007/s12975-023-01137-5. Epub 2023 Feb 11.
13

Pharmacokinetics, pharmacodynamics and safety of oral formulation (CG-750) of ivaltinostat, a histone deacetylase inhibitor, compared to IV formulation (CG-745)

Byungwook Kim, Ki Young Huh, Kyung-Sang Yu, SeungHwan Lee

British journal of clinical pharmacology. 2024,Apr;90(4):1103-1114. doi: 10.1111/bcp.15997. Epub 2024 Jan 23.
14

A Population Pharmacokinetic Study to Compare a Novel Empagliflozin L-Proline Formulation with Its Conventional Formulation in Healthy Subjects

Xu Jiang, Kyung-Sang Yu, Dong Hyuk Nam, Jaeseong Oh

Pharmaceuticals (Basel) 2024,Apr;17(4):522. doi: 10.3390/ph17040522.
15

Safety, Tolerability, and Pharmacokinetics of a Novel Macrocyclic Gadolinium-Based Contrast Agent, HNP-2006, in Healthy Subjects

Ki Young Huh, Woo Kyung Chung, Heejeong Lee, Seung Hong Choi, Kyung-Sang Yu, SeungHwan Lee

Investigative radiology. 2024,Mar;1;59(3):252-258.
16

Synergistic toxicity with copper contributes to NAT2-associated isoniazid toxicity

Jihoon G Yoon, Dong Geon Jang, Sung-Gyu Cho, Chaeyoung Lee, Shin Hye Noh, Soo Kyung Seo, Jung Woo Yu, Hyeon Woo Chung 3, KyeoRe Han, Soon Sung Kwon, Dai Hoon Han, Jaeseong Oh, In-Jin Jang, Sang-Hoon Kim, Young-Koo Jee, Hyun Lee, Dong Won Park, Jang Won S

Experimental & molecular medicine. 2024,Mar;1. doi: 10.1038/s12276-024-01172-8. Online ahead of print.
17

Profiling of endogenous metabolites and changes in intestinal microbiota distribution after GEN-001 ( Lactococcus lactis) administration

Min-Gul Kim, Suin Kim, Ji-Young Jeon, Seol Ju Moon, Yong-Geun Kwak 1 3, Joo Young Na 5, SeungHwan Lee, Kyung-Mi Park, Hyo-Jin Kim, Sang-Min Lee, Seo-Yeon Choi, Kwang-Hee Shin

Korean J Physiol Pharmacol. 2024,Mar; 1;28(2):153-164. doi: 10.4196/kjpp.2024.28.2.153.
18

Effects of meal type on the bioavailability of vutiglabridin, a novel anti-obesity agent, in healthy subjects

Heejae Won, Deok Yong Yoon, Sangmi Lee, Joo-Youn Cho, Jaeseong Oh, In-Jin Jang, Sang-Ku Yoo, Kyung-Sang Yu

Clin Transl Sci 2024,Mar;17(3):e13744. doi: 10.1111/cts.13744.
19

Estimation of the benefit from pre-emptive genotyping based on the nationwide cohort data in South Korea

Ki Young Huh, Sejung Hwang, Joo Young Na, Kyung-Sang Yu, In-Jin Jang, Jae-Yong Chung, Seonghae Yoon

Clin Transl Sci 2024,Mar;17(3):e13772. doi: 10.1111/cts.13772.
20

Establishment of Advanced Regulatory Innovation for Clinical Trials Transformation (ARICTT): a multi-stakeholder public-private partnership-based organization to accelerate the transformation of clinical trials

Woo Kyung Chung, Ki Young Huh, Jiyeon Park, Jaeseong Oh, Kyung-Sang Yu

Transl Clin Pharmacol 2024,Mar;32(1):30-40. doi: 10.12793/tcp.2024.32.e1. Epub 2024 Feb 20.
21

The landscape of decentralized clinical trials (DCTs): focusing on the FDA and EMA guidance

Jiyeon Park, Ki Young Huh, Woo Kyung Chung, Kyung-Sang Yu

Transl Clin Pharmacol 2024,Mar;32(1):41-51. doi: 10.12793/tcp.2024.32.e2. Epub 2024 Feb 20.
22

Topiramate dosage optimization for effective antiseizure management via population pharmacokinetic modeling

Seolah Lee, Hyun Chul Kim, Yoonhyuk Jang, Han Sang Lee, Seon-Jae Ahn, Soon-Tae Lee, Keun-Hwa Jung, Kyung-Il Park, Ki-Young Jung, Jaeseong Oh, SeungHwan Lee, Kyung-Sang Yu, In-Jin Jang, Soyoung Lee, Kon Chu, Sang Kun Lee

Annals of clinical and translational neurology. 2024,Feb;11(2):424-435. doi: 10.1002/acn3.51962. Epub 2023 Dec 7.
23

Evaluation of Food Effect on the Pharmacokinetics of Velufenacin, a New Muscarinic Receptor Antagonist, in Healthy Subjects

Juyoung Khwarg, Woo Kyung Chung, Soyoung Lee, Eunsol Yang, Chaelim Ryu, Dae Young Lee, Min Jung Lee, In-Jin Jang, Kyung-Sang Yu, SeungHwan Lee

Clinical pharmacology in drug development. 2024,Feb;13(2):128-133. doi: 10.1002/cpdd.1361. Epub 2023 Dec 29.
24

Effects of food and ethnicity on the pharmacokinetics of venadaparib, a next-generation PARP inhibitor, in healthy Korean, Caucasian, and Chinese male subjects

Hyun Chul Kim, Eunsol Yang, Soyoung Lee, Jaeseong Oh, Myongjae Lee, ChaeEun Lee, Kyoung Soo Ha, Won Sik Lee, In-Jin Jang, Kyung-Sang Yu

Investigational new drugs. 2024,Feb;42(1):80-88. doi: 10.1007/s10637-023-01405-z. Epub 2023 Dec 15.
25

Pharmacokinetic Comparison Between a Fixed-Dose Combination of Atorvastatin/Omega-3-Acid Ethyl Esters and the Corresponding Loose Combination in Healthy Korean Male Subjects

Juyoung Khwarg, Soyoung Lee, In-Jin Jang, Won-Ho Kang, Hye Jung Lee, Kyu Yeon Kim, Ki-Sun Jeong, Chongho Won, Youn Woong Choi 5, Dae Chul Ha 5, RaeHoon Jung 5, Min-Gu Han, Won Tae Jung, Kyu-Yeol Nam, YeSeul Kim, Kyung-Sang Yu, Jaeseong Oh

Drug design, development and therapy. 2024,Feb;8:18:395-406.
26

Pharmacogenetic Analysis of an 8-Year Old Girl with Reye Syndrome Associated with Use of Naproxen

Byungwook Kim, Joo-Youn Cho, Ildae Song, Jaeseong Oh

The American journal of case reports. 2024,Feb;5:25:e942242. doi: 10.12659/AJCR.942242.
27

Differences in Brain Metabolite Profiles Between Normothermia and Hypothermia

Suk Ho Sohn, Sihyun Chae, Jae Woong Choi, Karam Nam, Youn Joung Cho, Joo-Youn Cho, Ho Young Hwang

Journal of Korean medical science. 2024,Feb;26;39(7):e79. doi: 10.3346/jkms.2024.39.e79.
28

Metabolomic Characteristics of Nontuberculous Mycobacterial Pulmonary Disease

Jungeun Kim, Woori Chae, Joong-Yub Kim, Jae-Joon Yim, Joo-Youn Cho, Nakwon Kwak

J Infect Dis 2024,Feb;doi: 10.1093/infdis/jiae100. Online ahead of print.
29

A 6-month exercise intervention clinical trial in women: effects of physical activity on multi-omics biomarkers and health during the first wave of COVID-19 in Korea

JooYong Park, Jaemyung Kim, Jihyun Kang, Jaesung Choi, Ji-Eun Kim, Kyung-Joon Min, Seong-Woo Choi, Joo-Youn Cho, Miyoung Lee, Ji-Yeob Choi

BMC sports science, medicine and rehabilitation 2024,Jan;29;16(1):30. doi: 10.1186/s13102-024-00824-6.
30

Pharmacokinetic Comparison Between a Fixed-Dose Combination of Empagliflozin L-Proline/Metformin and Empagliflozin/Metformin in Healthy Korean Subjects

HyunJoon Lee, Jae-Yong Chung, Kyung-Sang Yu, Shin-Jung Park, Soyoung Lee

Clinical pharmacology in drug development. 2023,Dec;12(12):1156-1163. doi: 10.1002/cpdd.1310. Epub 2023 Jul 25.
31

Adaptive design clinical trials: current status by disease and trial phase in various perspectives

Hyunjoon Lee, Sejung Hwang, In-Jin Jang, Jae-Yong Chung, Jaeseong Oh

Translational and clinical pharmacology. 2023,Dec;31(4):202-216. doi: 10.12793/tcp.2023.31.e21. Epub 2023 Dec 21.
32

Feasibility study for a fully decentralized clinical trial in participants with functional constipation symptoms

Ki Young Huh, Woo Kyung Chung, Jiyeon Park, SeungHwan Lee, Min-Gul Kim, Jaeseong Oh, Kyung-Sang Yu

Clinical and translational science. 2023,Nov;16(11):2177-2188. doi: 10.1111/cts.13617. Epub 2023 Sep 8.
33

Intravitreal injectable hydrogel rods with long-acting bevacizumab delivery to the retina

Simin Lee, Hye Kyoung Hong, Jae Shin Song, Sae Im Jeong, Jae Yong Chung, Se Joon Woo, Ki Dong Park

Acta Biomater 2023,Nov;171:273-288. doi: 10.1016/j.actbio.2023.09.025. Epub 2023 Sep 20.
34

Exploration of smart adherence-monitoring methods in vitamin D-deficient patients: A pilot feasibility clinical study

Ki Young Huh, Hwiwon Lee, SeungHwan Lee, Kyung-Sang Yu, Kyung Hwan Kim, Heejin Kim

Clinical and translational science. 2023,Oct;16(10):1866-1875. doi: 10.1111/cts.13594. Epub 2023 Jul 24.
35

Palmitoylation-driven PHF2 ubiquitination remodels lipid metabolism through the SREBP1c axis in hepatocellular carcinoma

Do-Won Jeong, Jong-Wan Park, Kyeong Seog Kim, Jiyoung Kim, June Huh, Jieun Seo, Ye Lee Kim, Joo-Youn Cho, Kwang-Woong Lee, Junji Fukuda, Yang-Sook Chun

Nat Commun 2023,Oct;14(1):6370. doi: 10.1038/s41467-023-42170-0.
36

Pharmacokinetic and pharmacodynamic exploration of various combinations of tegoprazan immediate and delayed-release formulations

Sooyoun Park, Eunsol Yang, Byungwook Kim, Jihoon Kwon, In-Jin Jang, Seung Hwan Lee

British journal of clinical pharmacology. 2023,Sep;89(9):2877-2887. doi: 10.1111/bcp.15784. Epub 2023 Jun 1.
37

Semimechanistic pharmacokinetic-pharmacodynamic model of tripegfilgrastim for pediatric patients after chemotherapy

Soyoung Lee, Kyung Taek Hong, In-Jin Jang, Kyung-Sang Yu, Hyoung Jin Kang, Jaeseong Oh

CPT: pharmacometrics & systems pharmacology. 2023,Sep;;12(9):1319-1334. doi: 10.1002/psp4.13012. Epub 2023 Aug 9.
38

Immunogenicity and safety of SARS-CoV-2 recombinant protein nanoparticle vaccine GBP510 adjuvanted with AS03: interim results of a randomised, active-controlled, observer-blinded, phase 3 trial

Joon Young Song, Won Suk Choi, Jung Yeon Heo, Eun Jin Kim, Jin Soo Lee, Dong Sik Jung, Shin-Woo Kim, Kyung-Hwa Park, Joong Sik Eom, Su Jin Jeong, Jacob Lee, Ki Tae Kwon, Hee Jung Choi, Jang Wook Sohn, Young Keun Kim, Byung Wook Yoo, In-Jin Jang, Maria Z Caped

EClinicalMedicine. 2023,Sep;7:64:102140. doi: 10.1016/j.eclinm.2023.102140. eCollection 2023 Oct.
39

Quantification of OATP1B1 endogenous metabolites coproporphyrin I and III in human urine

Yeonseo Jang, Jihyun Kang, Sejung Hwang, Jae-Yong Chung, Joo-Youn Cho

Translational and clinical pharmacology. 2023,Sep;31(3):139-147. doi: 10.12793/tcp.2023.31.e12. Epub 2023 Aug 23.
40

Effects of rifampin coadministration on the pharmacokinetics of digoxin: a real-world data approach

JungJin Oh, Byungwook Kim, SeungHwan Lee

Transl Clin Pharmacol 2023,Sep;31(3):148-153. doi: 10.12793/tcp.2023.31.e13. Epub 2023 Sep 8.
41

Effect of Food on the Pharmacokinetics and Pharmacodynamics of a Novel Dual Delayed-Release Formulation of Esomeprazole in Healthy Subjects

Sejung Hwang, Sung Hee Hong, Jina Jung, Jae-Yong Chung, In-Jin Jang, SeungHwan Lee

Clinical pharmacology in drug development. 2023,Aug;12(8):839-844. doi: 10.1002/cpdd.1237. Epub 2023 Mar 16.
42

Safety, tolerability, pharmacokinetic/pharmacodynamic characteristics of bersiporocin, a novel prolyl-tRNA synthetase inhibitor, in healthy subjects

Min Young Park, Sungyeun Bae, Jung A Heo, Mihee Park, YuKyung Kim, Jumi Han, In-Jin Jang, Kyung-Sang Yu, Jaeseong Oh

Clinical and translational science. 2023,Jul;16(7):1163-1176. doi: 10.1111/cts.13518. Epub 2023 Apr 24.
43

Comparison of the Pharmacokinetics, Safety, and Tolerability of Two Empagliflozin Formulations in Healthy Korean Subjects

Xu Jiang, Sungyeun Bae, Deok Yong Yoon, Shin Jung Park, Jaeseong Oh, Joo-Youn Cho, Kyung-Sang Yu

Drug design, development and therapy. 2023,Jul; 24;17:2137-2145. doi: 10.2147/DDDT.S409368. eCollection 2023.
44

Continuous versus intermittent infusion of human antithrombin III concentrate in the immediate postoperative period after liver transplantation

Bo Rim Kim, Leerang Lim, YoungRok Choi, Nam-Joon Yi, Kwang-Woong Lee 3, Kyung-Suk Suh 3, Kyung-Sang Yu, Jin Young Sohn, Raewon Jeong, Jaeseong Oh, Ho Geol Ryu

Clinical and translational science. 2023,Jul;16(7):1177-1185. doi: 10.1111/cts.13521. Epub 2023 Apr 24.
45

Exploring the Category and Use Cases on Digital Therapeutic Methodologies

Sunhee An, Jieun Ko, Kyung-Sang Yu, Hyuktae Kwon, Sungwan Kim, Jeeyoung Hong, Hyoun-Joong Kong

Healthcare informatics research. 2023,Jul;29(3):190-198. doi: 10.4258/hir.2023.29.3.190. Epub 2023 Jul 31.
46

Pharmacokinetic and pharmacodynamic interaction of DWP16001, a sodium-glucose cotransporter 2 inhibitor, with gemigliptin and metformin in healthy adults

Sae Im Jeong, Yun Kim, Jae Jin Nah, Wan Huh, In-Jin Jang, Jun Gi Hwang, SeungHwan Lee

British journal of clinical pharmacology. 2023,Jun;89(6):1780-1788. doi: 10.1111/bcp.15632. Epub 2023 Jan 4.
47

Prediction of gastric pH-mediated drug exposure using physiologically-based pharmacokinetic modeling: A case study of itraconazole

Eunsol Yang, Kyung-Sang Yu, SeungHwan Lee

CPT: pharmacometrics & systems pharmacology. 2023,Jun;12(6):865-877. doi: 10.1002/psp4.12959. Epub 2023 Mar 26.
48

Effect of haemodialysis on the pharmacokinetics and pharmacodynamics of evogliptin

Byungwook Kim, Dha Woon Im, Heejae Won, Jung Sunwoo, Seung Seok Han, Hajeong Lee, Dong Ki Kim, Kook-Hwan Oh, Kwon Wook Joo, Yon Su Kim, Joo-Youn Cho, SeungHwan Lee, Jaeseong Oh, In-Jin Jang, Yong Chul Kim

Diabetes, obesity and metabolism 2023,Jun;25(6):1769-1776. doi: 10.1111/dom.15034. Epub 2023 Apr 3.
49

Population Pharmacokinetic-Pharmacodynamic Modeling of Carvedilol to Evaluate the Effect of Cytochrome P450 2D6 Genotype on the Heart Rate Reduction

Sejung Hwang, Soyoung Lee, Jangsoo Yoon, Jae-Yong Chung

J Korean Med Sci 2023,Jun;38(22):e173. doi: 10.3346/jkms.2023.38.e173.
50

Pharmacokinetics and safety of candidate tocilizumab biosimilar CT-P47 versus reference tocilizumab: a randomized, double-blind, single-dose phase I study

Kyung-Sang Yu, Byungwook Kim, Dongseong Shin, Min Kyu Park, Jun Gi Hwang, Min-Gul Kim, Hyewon Chung, JongLyul Ghim, Jae-Yong Chung, Josef S Smolen, Gerd R Burmester, SungHyun Kim, YunJu Bae, DaBee Jeon, JaeKyoung Yoo, GoEun Yang, JiHun Bae, Edward Keystone

Expert opinion on investigational drugs. 2023,May;;32(5):429-439. doi: 10.1080/13543784.2023.2212155. Epub 2023 May 26.
51

Serum, Urine, and Fecal Metabolome Alterations in the Gut Microbiota in Response to Lifestyle Interventions in Pediatric Obesity: A Non-Randomized Clinical Trial

Yujin Lee, Joo-Youn Cho, Ky Young Cho

Nutrients 2023,May;15(9):2184. doi: 10.3390/nu15092184.
52

Randomised clinical trial: Safety, tolerability, pharmacodynamics and pharmacokinetics of zastaprazan (JP-1366), a novel potassium-competitive acid blocker, in healthy subjects

Inyoung Hwang, Sang Chun Ji, Jaeseong Oh, Hyojin Kim, Hyunju Cha, Jonhn Kim, Chang-Seok Lee, Kyug-Sang Yu, SeungHwan Lee

Alimentary pharmacology & therapeutics. 2023,Apr;57(7):763-772. doi: 10.1111/apt.17406. Epub 2023 Feb 2.
53

Evaluation of CYP2C19-Mediated Pharmacokinetic Drug Interaction of Tegoprazan, Compared with Vonoprazan or Esomeprazole

Eunsol Yang, Sang Chun Ji, In-Jin Jang, SeungHwan Lee

Clinical pharmacokinetics. 2023,Apr;62(4):599-608. doi: 10.1007/s40262-023-01228-4. Epub 2023 Mar 10.
54

Editorial: deja vu all over again - let the P-CAB wars begin. Authors' reply

Inyoung Hwang, SeungHwan Lee

Alimentary pharmacology & therapeutics. 2023,Apr;57(8):914-915. doi: 10.1111/apt.17444.
55

Pharmacokinetic and pharmacodynamic interaction between DWP16001, an sodium-glucose cotransporter 2 inhibitor and metformin in healthy subjects

Byungwook Kim, Ki Young Huh, Jun Gi Hwang, JaeJin Nah, Wan Huh, Jae Min Cho, In-Jin Jang, Kyung-Sang Yu, Yun Kim, SeungHwan Lee

British journal of clinical pharmacology. 2023,Apr;89(4):1462-1470. doi: 10.1111/bcp.15613. Epub 2022 Dec 8.
56

A Comparison of the Pharmacokinetics and Safety of Dapagliflozin Formate, an Ester Prodrug of Dapagliflozin, to Dapagliflozin Propanediol Monohydrate in Healthy Subjects

Hyun Chul Kim, Sangmi Lee, Siyoung Sung, Eunjin Kim, In-Jin Jang, Jae-Yong Chung

Drug design, development and therapy. 2023,Apr;17:1203-1210. doi: 10.2147/DDDT.S404182. eCollection 2023.
57

Pharmacokinetics and Pharmacodynamics of Esomezol DR, a New Dual Delayed-Release Formulation of Esomeprazole 20 Mg or 40 Mg, in Healthy Subjects

Hyun Chul Kim, Eunsol Yang, Mu Seong Ban, Yu Kyong Kim, Sung Hee Hong, Jina Jung, In-Jin Jang, SeungHwan Lee

Drug design, development and therapy. 2023,Apr;12;17:1115-1124. doi: 10.2147/DDDT.S392533. eCollection 2023.
58

Pharmacokinetics of dexmedetomidine in pediatric patients undergoing cardiac surgery with cardiopulmonary bypass

Eun-Hee Kim, Byung-Moon Choi, Pyoyoon Kang, Ji-Hyun Lee, Hee-Soo Kim, Young-Eun Jang, Sang-Hwan Ji, Gyu-Jeong Noh, Joo-Youn Cho, Jin-Tae Kim

Pediatric anesthesia 2023,Apr;33(4):303-311. doi: 10.1111/pan.14626. Epub 2023 Jan 16.
59

Conventional reversal of rocuronium-induced neuromuscular blockade by sugammadex in Korean children: pharmacokinetics, efficacy, and safety analyses

Sang-Hwan Ji, Ki Young Huh, Jaeseong Oh, Hee-Jeong Jeong, Young-Eun Jang, Eun-Hee Kim, Ji-Hyun Lee, Jin-Tae Kim, Hee-Soo Kim

Frontiers in pharmacology 2023,Apr;13;14:1127932. doi: 10.3389/fphar.2023.1127932. eCollection 2023.
60

Evaluation of Vancomycin TDM Strategies: Prediction and Prevention of Kidney Injuries Based on Vancomycin TDM Results

Byungwook Kim, Sejung Hwang, Eunjeong Heo, Hyung-Sook Kim, Jongtak Jung, Eu Suk Kim, Hong Bin Kim, Kyunghoon Lee, Jeong Su Park, Junghan Song, Joon Hee Lee, Jae-Yong Chung, Kyoung-Ho Song, Seonghae Yoon

J Korean Med Sci 2023,Apr;38(14):e101. doi: 10.3346/jkms.2023.38.e101.
61

Pharmacokinetics, safety and tolerability of valbenazine in Korean CYP2D6 normal and intermediate metabolizers

Woo Kyung Chung, Inyoung Hwang, Byungwook Kim, Jihyun Jung, Kyung-Sang Yu, In-Jin Jang, Jaeseong Oh

Clinical and translational science. 2023,Mar;16(3):512-523. doi: 10.1111/cts.13466. Epub 2022 Dec 27.
62

Analysis of the distribution of trial sites in South Korea using social network analysis

Ki Young Huh, Kyung-Sang Yu, Ildae Song

Translational and clinical pharmacology. 2023,Mar;;31(1):1-12. doi: 10.12793/tcp.2023.31.e2. Epub 2023 Mar 22.
63

Baseline Tyrosine Level Is Associated with Dynamic Changes in FAST Score in NAFLD Patients under Lifestyle Modification

Hwi Young Kim, Da Jung Kim, Hye Ah Lee, Joo-Youn Cho, Won Kim

Metabolites 2023,Mar;17;13(3):444. doi: 10.3390/metabo13030444.
64

Development of a Fast Onset Proton Pump Inhibitor: Comparison of Fixed-Dose Combination of Rabeprazole and Sodium Bicarbonate (YPI-011) to the Conventional Enteric-Coated Rabeprazole

Sungyeun Bae, Jihoon Kwon, Mi-Hye Lee, Kyung-Sang Yu, SeungHwan Lee

Drug design, development and therapy. 2023,Feb;15;17:497-506. doi: 10.2147/DDDT.S391716. eCollection 2023.
65

Pharmacodynamic and Pharmacokinetic Drug Interactions between Fexuprazan, a Novel Potassium-Competitive Inhibitor, and Aspirin, in Healthy Subjects

JungJin Oh, Eunsol Yang, In-Jin Jang, Hyejung Lee, Hokyun Yoo, Jae-Yong Chung, SeungHwan Lee, Jaeseong Oh

Pharmaceutics. 2023,Feb; 7;15(2):549. doi: 10.3390/pharmaceutics15020549.
66

Dynamic changes in clinical biomarkers of cardiometabolic diseases by changes in exercise behavior, and network comparisons: a community-based prospective cohort study in Korea

JooYong Park, Jaesung Choi, Ji-Eun Kim, Sang-Min Park, Joo-Youn Cho, Daehee Kang, Miyoung Lee, Ji-Yeob Choi

Epidemiology and health. 2023,Feb;;45:e2023026. doi: 10.4178/epih.e2023026. Epub 2023 Feb 16.
67

Effects of food and race on the pharmacokinetics of lazertinib in healthy subjects and patients with EGFR mutation-positive advanced non-small cell lung cancer

Ki Young Huh, Yeji Lim, Deok Yong Yoon, Jun Gi Hwang, Sujin Sim, Jiah Kang, Jangyoung Wang, Mikyung Kim, Seong Bok Jang, S Martin Shreeve, Jaydeep Mehta, Nahor Haddish-Berhane, Jaeseong Oh, SeungHwan Lee, Kyung-Sang Yu

LUNG CANCER 2023,Jan;;175:112-120. doi: 10.1016/j.lungcan.2022.11.021. Epub 2022 Dec 2.
68

Evaluation of Safety, Tolerability and Pharmacokinetic Characteristics of SA001 and Its Active Metabolite Rebamipide after Single and Multiple Oral Administration

Sungyeun Bae, Ki Young Huh, Jaeseong Oh, Kyung-Sang Yu, Anhye Kim

Pharmaceuticals. 2023,Jan;16;16(1):132. doi: 10.3390/ph16010132.
69

Comparison of Pharmacodynamics between Tegoprazan and Dexlansoprazole Regarding Nocturnal Acid Breakthrough: A Randomized Crossover Study. Gut Liver.

Sungpil Han, Hee Youn Choi, Yo Han Kim, SeungChan Choi, Seokuee Kim, Ji Yeon Nam, Bongtae Kim, Geun Seog Song, Hyeong-Seok Lim, Kyun-Seop Bae

Gut and liver 2023,Jan;15;17(1):92-99. doi: 10.5009/gnl220050. Epub 2022 Nov 1.
70

Reversal of rocuronium-induced intense neuromuscular blockade by sugammadex in Korean children: A pharmacokinetic and pharmacodynamic analysis

Sang-Hwan Ji, Ki Young Huh, Jaeseong Oh, Hee-Jeong Jeong, Young-Eun Jang, Eun-Hee Kim, Ji-Hyun Lee, Jin-Tae Kim, Hee-Soo Kim

Clinical and translational science. 2023,Jan;16(1):92-103. doi: 10.1111/cts.13429. Epub 2022 Oct 17.
71

Protective role of colitis in inflammatory arthritis via propionate-producing Bacteroides in the gut

Hoh-Jeong Shon, Yu-Mi Kim, Kyeong Seog Kim, Jin-Ouk Choi, Sang-Hyun Cho, Sujin An, Se-Hyeon Park, Yong-Joon Cho, Joo-Hong Park, Sang-Uk Seo, Joo-Youn Cho, Wan-Uk Kim, Donghyun Kim

Frontiers in immunology. 2023,Jan; 30;14:1064900. doi: 10.3389/fimmu.2023.1064900. eCollection 2023.
72

Adherence and persistence rates of major antidiabetic medications: a review

David Seung U Lee, Howard Lee

Diabetol Metab Syndr 2023,Jan;14(1):12. doi: 10.1186/s13098-022-00785-1.
73

Evaluation of drug prescribing patterns and therapeutic drug monitoring practice using electronic medical records

Sangmi Lee, Seonghae Yoon, In-Jin Jang

Scientific reports. 2022,Dec;9;12(1):21377. doi: 10.1038/s41598-022-25794-y.
74

Pharmacokinetic evaluation of radiolabeled intraocular anti-CLEC14a antibody in preclinical animal species and application in humans

Sohyun Park, Youn Woo Lee, Jaeseong Oh, Su Jin Kim, Sukmook Lee, Ho-Young Lee

Clinical and translational science. 2022,Dec;15(12):2938-2946. doi: 10.1111/cts.13412. Epub 2022 Sep 27.
75

A single administration of hIL-7-hyFc induces long-lasting T-cell expansion with maintained effector functions

Sojeong Kim, Sang Won Lee, June-Young Koh, Donghoon Choi, Minkyu Heo, Jae-Yong Chung, Byung Ha Lee, Se Hwan Yang, Young Chul Sung, Howard Lee, Eui-Cheol Shin, Su-Hyung Park

Blood Adv 2022,Dec;6(23):6093-6107. doi: 10.1182/bloodadvances.2021006591.
76

Safety, tolerability, pharmacokinetic, and pharmacodynamic characteristics of vutiglabridin: A first-in-class, first-in-human study

Joo Young Na, Deok Yong Yoon, Hyounggyoon Yoo, SeungHwan Lee, Kyung-Sang Yu, In-Jin Jang, Sang-Ku Yoo, Youngah Kim, Jaeseong Oh

Clinical and translational science. 2022,Nov;;15(11):2744-2757. doi: 10.1111/cts.13401. Epub 2022 Oct 10.
77

Effects of CYP2C19 genetic polymorphisms on the pharmacokinetics of lacosamide in Korean patients with epilepsy

Seon-Jae Ahn, Jaeseong Oh, Do-Yong Kim, Hyoshin Son, Sungeun Hwang, Hye-Rim Shin, Eun Young Kim, Han Sang Lee, Woo-Jin Lee, Jangsup Moon, Soon-Tae Lee, Keun-Hwa Jung, Kyung-Il Park, Ki-Young Jung, SeungHwan Lee, Kyung-Sang Yu, Kon Chu, Sang Kun Lee

EPILEPSIA 2022,Nov;63(11):2958-2969. doi: 10.1111/epi.17399. Epub 2022 Aug 30.
78

Efficacy and safety of a new ranibizumab biosimilar CKD-701 using a pro re nata treatment regimen in neovascular age-related macular degeneration: A phase 3 randomized clinical trial

Chang Ki Yoon, Jaeryung Oh, Kunho Bae, Un Chul Park, Kyung-Sang Yu, Hyeong Gon Yu

PloS one. 2022,Nov;14;17(11):e0275611. doi: 10.1371/journal.pone.0275611. eCollection 2022.
79

A database of 5305 healthy Korean individuals reveals genetic and clinical implications for an East Asian population

Jeongeun Lee, Jean Lee, Sungwon Jeon, Jeongha Lee, Insu Jang, Jin Ok Yang, Soojin Park, Byungwook Lee, Jinwook Choi, Byung-Ok Choi, Heon Yung Gee, Jaeseong Oh, In-Jin Jang, Sanghyuk Lee, Daehyun Baek, Youngil Koh, Sung-Soo Yoon, Young-Joon Kim, Jong

Experimental & molecular medicine. 2022,Nov;54(11):1862-1871. doi: 10.1038/s12276-022-00871-4. Epub 2022 Nov 2.
80

Identification of Serum Metabolites for Predicting Chronic Kidney Disease Progression according to Chronic Kidney Disease Cause

Eunjeong Kang, Yufei L, Bora Kim, Ki Young Huh, Miyeun Han, Jung-Hyuck Ahn 5, Hye Youn Sung 5, Yong Seek Park 6, Seung Eun Lee, Sangjun Lee, Sue K Park, Joo-Youn Cho, Kook-Hwan Oh

Metabolites. 2022,Nov;16;12(11):1125. doi: 10.3390/metabo12111125.
81

Safety, Tolerability, and Serum/Tear Pharmacokinetics of Human Recombinant Epidermal Growth Factor Eyedrops in Healthy Subjects

Hyounggyoon Yoo, Seonghae Yoon, In-Jin Jang, Kyung-Sang Yu, Joon Young Hyon , Jungi Hwang, Inyoung Hwang, Jung Sunwoo, Jae-Yong Chung

Pharmaceuticals 2022,Oct;24;15(11):1312. doi: 10.3390/ph15111312.
82

Identification of Metabolic Signature Associated with Idiopathic Inflammatory Myopathy Reveals Polyamine Pathway Alteration in Muscle Tissue

Jihyun Kang, Jeong Yeon Kim, Youjin Jung, Seon Uk Kim, Eun Young Lee, Joo-Youn Cho

Metabolites. 2022,Oct;21;12(10):1004. doi: 10.3390/metabo12101004.
83

Induction of the hepatic aryl hydrocarbon receptor by alcohol dysregulates autophagy and phospholipid metabolism via PPP2R2D

Yun Seok Kim, Bongsub Ko, Da Jung Kim, Jihoon Tak, Chang Yeob Han, Joo-Youn Cho, Won Kim, Sang Geon Kim

Nat Commun 2022,Oct;13(1):6080. doi: 10.1038/s41467-022-33749-0.
84

Spouse bereavement and brain pathologies: A propensity score matching study

Jee Wook Kim, Min Soo Byun, Jun Ho Lee, Dahyun Yi, Min Jung Kim, Gijung Jung, Jun-Young Lee, Yun-Sang Lee, Yu Kyeong Kim, Koung Mi Kang, Chul-Ho Sohn, Dong Young Lee; KBASE Research Group

Psychiatry Clin Neurosci 2022,Oct;76(10):490-504. doi: 10.1111/pcn.13439. Epub 2022 Jul 18. KBASE Research Group(조)
85

Dose-dependent glucosuria of DWP16001, a novel selective sodium-glucose cotransporter-2 inhibitor, in healthy subjects

Jun Gi Hwang, SeungHwan Lee, Wan Huh, Jumi Han, Jaeseong Oh, In-Jin Jang, Kyung-Sang Yu

British journal of clinical pharmacology 2022,Sep;88(9):4100-4110. doi: 10.1111/bcp.15348. Epub 2022 Apr 22.
86

The pharmacokinetic, safety, and tolerability profiles of eslicarbazepine acetate are comparable between Korean and White subjects

Sejung Hwang, Soyoung Lee, Eunwoo Kim, Inyoung Hwang, Joo-Youn Cho , Jae-Yong Chung, In-Jin Jang, Jaeseong Oh

Clinical and translational science. 2022,Sep;15(9):2116-2126. doi: 10.1111/cts.13344. Epub 2022 Jun 21.
87

A population PK-PD model of YH4808, a novel P-CAB, and intragastric pH that incorporated negative feedback by increased intragastric pH onto the systemic exposure to YH4808

Tae Kyu Chung, Hyun A Lee, Kyeong-Ryoon Lee, Seong Bok Jang, Kyung-Sang Yu, Howard Lee

CPT: pharmacometrics & systems pharmacology. 2022,Sep;11(9):1223-1233. doi: 10.1002/psp4.12839. Epub 2022 Jul 9.
88

Considerations for clinical evaluation of the effects of bariatric surgery on the pharmacokinetics of orally administered drugs

Sungyeun Bae, JungJin Oh, Ildae Song, Kyung-Sang Yu, SeungHwan Lee

Translational and clinical pharmacology. 2022,Sep;30(3):145-154. doi: 10.12793/tcp.2022.30.e15. Epub 2022 Sep 26.
89

Association of Metabolic Signatures with Nonalcoholic Fatty Liver Disease in Pediatric Population

Woori Chae, Kyung Jae Lee, Ki Young Huh, Jin Soo Moon, Jae Sung Ko, Joo-Youn Cho

Metabolites . 2022,Sep;19;12(9):881. doi: 10.3390/metabo12090881.
90

Factors affecting the changes in antihypertensive medications in patients with hypertension

Tae Kyu Chung, Yoomin Jeon, YeSol Hong, Suyeon Hong, Jun Sik Moon, Howard Lee

Front Cardiovasc Med 2022,Sep;9:999548. doi: 10.3389/fcvm.2022.999548. eCollection 2022.
91

How to boost and accelerate new drug development in Korea: business ecosystem perspectives

Yoona Choi, Howard Lee

Transl Clin Pharmacol 2022,Sep;30(3):129-135. doi: 10.12793/tcp.2022.30.e17. Epub 2022 Sep 27.
92

Dose-dependent reduction of lymphocyte count and heart rate after multiple administration of LC51-0255, a novel sphingosine-1-phosphate receptor 1 modulator, in healthy subjects

Inyoung Hwang, Sang Won Lee, Jaeseong Oh, SeungHwan Lee, In-Jin Jang, Kyung-Sang Yu

Front Pharmacol 2022,Aug;13:930615. doi: 10.3389/fphar.2022.930615. eCollection 2022.
93

Night-time gastric acid suppression by tegoprazan compared to vonoprazan or esomeprazole

Eunsol Yang, Seokuee Kim, Bongtae Kim, Boram Kim, Yechan Kim, Sung Sup Park, Geun Seog Song, Kyung-Sang Yu, In-Jin Jang, Seung Hwan Lee

British journal of clinical pharmacology. 2022,Jul;;88(7):3288-3296. doi: 10.1111/bcp.15268. Epub 2022 Feb 23.
94

Clinical Evaluation of Digital Therapeutics: Present and Future

Ki Young Huh, Jaeseong Oh, SeungHwan Lee, Kyung-Sang Yu

Healthcare informatics research. 2022,Jul;Jul;28(3):188-197. doi: 10.4258/hir.2022.28.3.188. Epub 2022 Jul 31.
95

Machine learning-based quantitative prediction of drug exposure in drug-drug interactions using drug label information

Ha Young Jang, Jihyeon Song, Jae Hyun Kim, Howard Lee, In-Wha Kim, Bongki Moon, Jung Mi Oh

NPJ Digit Med 2022,Jul;5(1):88. doi: 10.1038/s41746-022-00639-0.
96

Comparative pharmacokinetics between two tablets of tramadol 37.5 mg/acetaminophen 325 mg and one tablet of tramadol 75 mg/acetaminophen 650 mg for extended-release fixed-dose combination

Hyun Chul Kim, Deok Yong Yoon, SeungHwan Lee, In-Jin Jang, Jang Hee Hong, JaeWoo Kim

Translational and clinical pharmacology. 2022,Jun;Jun;30(2):112-119. doi: 10.12793/tcp.2022.30.e12. Epub 2022 Jun 27.
97

Key Considerations for Phase 2 or 3 Clinical Study Design of Anti-Inflammatory Agent for COVID-19 Treatment

Yewon Park, Joo Young Na, Joo-Youn Cho, Jaeseong Oh, Su-Jin Rhee

Frontiers in pharmacology. 2022,Jun;Jun 2;13:842836. doi: 10.3389/fphar.2022.842836. eCollection 2022.
98

An Improved Method to Quantify Short-Chain Fatty Acids in Biological Samples Using Gas Chromatography-Mass Spectrometry

Kyeong-Seog Kim, Yujin Lee, Woori Chae, Joo-Youn Cho

Metabolites 2022,Jun;Jun 7;12(6):525. doi: 10.3390/metabo12060525.
99

Therapeutic drug monitoring on the use of transplacental digoxin in fetal tachyarrhythmia: a case report

Sae Im Jeong, Heejae Won, Ildae Song, Jaeseong Oh

Translational and clinical pharmacology. 2022,Jun;Jun;30(2):83-86. doi: 10.12793/tcp.2022.30.e11. Epub 2022 Jun 22.
100

Population Pharmacokinetic Model of AST-001, L-Isomer of Serine, Combining Endogenous Production and Exogenous Administration in Healthy Subjects

Soyoung Lee, Su-Kyeong Hwang, Hee-Sook Nam, Jung-Sook Cho, Jae-Yong Chung

Frontiers in pharmacology. 2022,Jun;24;13:891227. doi: 10.3389/fphar.2022.891227. eCollection 2022.
101

Lessons from a multicenter clinical trial with an approved wearable electrocardiogram: issues and practical considerations

Ki Young Huh, Sae Im Jeong, Hyounggyoon Yoo, Meihua Piao, Hyeongju Ryu, Heejin Kim, Young-Ran Yoon, Sook Jin Seong, SeungHwan Lee, Kyung Hwan Kim

Transl Clin Pharmacol 2022,Jun;30(2):87-98. doi: 10.12793/tcp.2022.30.e7. Epub 2022 May 24.
102

Endogenous metabolic markers for predicting the activity of dihydropyrimidine dehydrogenase

Jihyun Kang, Andrew HyoungJin Kim, Inseung Jeon, Jaeseong Oh, In-Jin Jang, SeungHwan Lee, Joo-Youn Cho

Clinical and translational science. 2022,May; May;15(5):1104-1111. doi: 10.1111/cts.13203. Epub 2021 Dec 4.
103

Comparative Pharmacokinetics Between a Fixed-Dose Combination of Pitavastatin/Valsartan 4/160 mg and the Corresponding Individual Components Through a Partial Replicated Crossover Design in Healthy Male Subjects

Joo Young Na, Eunsol Yang, Jae-Hoon Kim, In Sun Kwon, Eun-Heui Jin, Kyung-Sang Yu, Jinsook Kim, SeungHwan Lee, Jang Hee Hong

Clinical pharmacology in drug development. 2022,May;;11(5):615-622. doi: 10.1002/cpdd.1054. Epub 2022 Jan 8.
104

Safety, tolerability, and pharmacokinetics of single and multiple topical ophthalmic administration of imatinib mesylate in healthy subjects

Joo Young Na, Ki Young Huh, Kyung-Sang Yu, Joon Young Hyon, Hye Cheong Koo, Jong Ho Lee, Ji Chang You , Jae-Yong Chung

Clinical and translational science. 2022,May;15(5):1123-1130. doi: 10.1111/cts.13226. Epub 2022 Feb 8.
105

Population pharmacokinetic analysis of sildenafil in term and preterm infants with pulmonary arterial hypertension

Su-Jin Rhee, Seung Han Shin, Jaeseong Oh, Young Hwa Jung, Chang Won Choi, Han-Suk Kim, Kyung-Sang Yu

Scientific Reports 2022,May;May 5;12(1):7393. doi: 10.1038/s41598-022-11038-6.
106

Evaluation of a blockchain-based dynamic consent platform (METORY) in a decentralized and multicenter clinical trial using virtual drugs

Ki Young Huh, Seol Ju Moon, Sang-Un Jeong, Min-Ji Kim, Wooseok Yang, Myeonggyu Jeong, Min-Gul Kim, SeungHwan Lee

Clin Transl Sci 2022,May;15(5):1257-1268. doi: 10.1111/cts.13246. Epub 2022 Feb 17.
107

METORY: Development of a Demand-Driven Blockchain-Based Dynamic Consent Platform Tailored for Clinical Trials

Ki Young Huh, Sang-Un Jeong, Seol Ju Moon, Min-Ji Kim, Wooseok Yang, Myeonggyu Jeong, Ildae Song, Yong-Geun Kwak, SeungHwan Lee, Min-Gul Kim

Front Med (Lausanne) 2022,May;9:837197. doi: 10.3389/fmed.2022.837197. eCollection 2022.
108

Single-dose of LC51-0255, a selective S1P 1 receptor modulator, showed dose-dependent and reversible reduction of absolute lymphocyte count in humans

Sang Won Lee, Inyoung Hwang, Jaeseong Oh, SeungHwan Lee, In-Jin Jang, Kyung-Sang Yu

Clinical and translational science 2022,Apr;Apr;15(4):1074-1083. doi: 10.1111/cts.13227. Epub 2022 Jan 23.
109

A double-blind, placebo-controlled, single-ascending dose study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of HM15136, a novel long-acting glucagon analogue, in healthy subjects

Ki Young Huh, Jun Gi Hwang, Wonjung Shin, Seungjae Baek, JaeDuk Choi, Nora Lee, Young Min Cho, Howard Lee

Diabetes, obesity & metabolism. 2022,Mar;4(3):411-420. doi: 10.1111/dom.14590. Epub 2021 Nov 24.
110

A Phase 1 Study to Evaluate the Safety and Pharmacokinetics following Administration of Single and Multiple Doses of the Anti-Staphylococcal Lysin, LSVT-1701, in Healthy Adult Subjects

Mary Beth Wire, Soo Youn Jun, In-Jin Jang, Seung-Hwan Lee, Jun Gi Hwang, David B Huang

Antimicrobial agents and chemotherapy 2022,Mar;66(3):e0184221. doi: 10.1128/AAC.01842-21. Epub 2022 Jan 10.
111

A Randomized, Double-Blind, Placebo- and Active-Controlled, Escalating Single-Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Profiles of Subcutaneous Eflapegrastim in Healthy Japanese and Caucasian Subjects

Yoomin Jeon, Nora Lee, Seungjae Baek, JaeDuk Choi, Stanford Jhee, Howard Lee

Drugs in R&D. 2022,Mar;22(1):71-87. doi: 10.1007/s40268-021-00379-8. Epub 2022 Jan 6.
112

Evaluation of food effects on the pharmacokinetics of Pelargonium sidoides and Coptis with each bioactive compound berberine and epicatechin after a single oral dose of an expectorant and antitussive agent UI026 in healthy subjects

Yewon Park, WonTae Jung, Eunsol Yang, Kyu-Yeol Nam, Woo-Ri Bong, Jaehee Kim, Kyu Yeon Kim, SeungHwan Lee, Joo-Youn Cho, Jang-Hee Hong, JaeWoo Kim

Translational and clinical pharmacology. 2022,Mar; Mar;30(1):49-56. doi: 10.12793/tcp.2022.30.e3. Epub 2022 Mar 7.
113

Exploration for the effect of renal function and renal replacement therapy on pharmacokinetics of remdesivir and GS-441524 in patients with COVID-19: A limited case series

Pyoeng Gyun Choe, Sae Im Jeong, Chang Kyung Kang, Liju Yang, SeungHwan Lee, Joo-Youn Cho, Seung Seok Han, Dong Ki Kim, Sang Min Lee, Wan Beom Park, Myoung-Don Oh, Nam Joong Kim

Clin Transl Sci 2022,Mar;15(3):732-740. doi: 10.1111/cts.13194. Epub 2021 Nov 20.
114

Pharmacokinetics and safety of cenobamate, a novel antiseizure medication, in healthy Japanese, and an ethnic comparison with healthy non-Japanese

Eunsol Yang, Jung Sunwoo, Ki Young Huh, Yu Kyong Kim, SeungHwan Lee, In-Jin Jang, Kyung-Sang Yu

Clinical and translational science. 2022,Feb;15(2):490-500. doi: 10.1111/cts.13167. Epub 2021 Oct 20.
115

A phase I study to evaluate the safety, tolerability, pharmacodynamic and pharmacokinetic profiles of ocular GLH8NDE in healthy male adults

Jihyun Jung, Ki Young Huh, Xuanyou Jin, Ahnul Ha, Ki Ho Park, Jun Sang Park, Eunjung Kim, Jaehwi Lee, In-Jin Jang, Howard Lee

Clinical and translational science. 2022,Feb; Feb;15(2):343-352. doi: 10.1111/cts.13150. Epub 2021 Sep 15.
116

Pharmacokinetics and safety of a novel influenza treatment (baloxavir marboxil) in Korean subjects compared with Japanese subjects

Yun Kim, Sangwon Lee, Yohan Kim, In-Jin Jang, SeungHwan Lee

Clinical and translational science. 2022,Feb; Feb;15(2):422-432. doi: 10.1111/cts.13160. Epub 2021 Oct 19.
117

An annotated corpus from biomedical articles to construct a drug-food interaction database

Siun Kim, Yoona Choi, Jung-Hyun Won, Jung Mi Oh, Howard Lee

Journal of biomedical informatics. 2022,Feb;126:103985. doi: 10.1016/j.jbi.2022.103985. Epub 2022 Jan 7.
118

Evaluation of safety and pharmacokinetics of bismuth-containing quadruple therapy with either vonoprazan or lansoprazole for Helicobacter pylori eradication

Ki Young Huh, Hyewon Chung, Yu Kyong Kim, Seung Hwan Lee, Siddharth Bhatia, Yohei Takanami, Ryou Nakaya, Kyung-Sang Yu

British journal of clinical pharmacology. 2022,Jan;88(1):138-144. doi: 10.1111/bcp.14934. Epub 2021 Jun 26.
119

Pharmacokinetic and Pharmacodynamic Characteristics of Tripegfilgrastim, a Pegylated G-CSF, in Pediatric Patients with Solid Tumors

Soyoung Lee, Kyung Taek Hong, Seol Ju Moon, Jung Yoon Choi, Che Ry Hong, Hee Young Shin, Joo-Youn Cho, In-Jin Jang, Kyung-Sang Yu, Jaeseong Oh, Hyoung Jin Kang

Clinical pharmacology and therapeutics. 2022,Jan;2022 Jan;111(1):293-301. doi: 10.1002/cpt.2433.
120

Cytoplasmic zinc promotes IL-1β production by monocytes and macrophages through mTORC1-induced glycolysis in rheumatoid arthritis

Bonah Kim, Hee Young Kim, Bo Ruem Yoon, Jina Yeo, Ji In Jung, Kyung-Sang Yu, Hyeon Chang Kim, Su-Jin Yoo, Jin Kyun Park, Seong Wook Kang, Won-Woo Lee

Science signaling. 2022,Jan;11;15(716):eabi7400. doi: 10.1126/scisignal.abi7400. Epub 2022 Jan 11.
121

Pharmacokinetics of a Fixed-Dose Combination of Amlodipine/Losartan and Chlorthalidone Compared to Concurrent Administration of the Separate Components

Inseung Jeon, Seol Ju Moon, Sang-In Park, Yewon Choi, Jina Jung, Kyung-Sang Yu, Jae-Yong Chung

Clinical pharmacology in drug development. 2022,Jan;11(1):91-99. doi: 10.1002/cpdd.963. Epub 2021 Jun 22.
122

Clinical Response and Hospital Costs of Therapeutic Drug Monitoring for Vancomycin in Elderly Patients

Yun Kim, Soohyun Kim, Jinsook Park, Howard Lee

J Pers Med 2022,Jan;12(2):163. doi: 10.3390/jpm12020163.
123

Influence of CYP2C19 Polymorphisms on the Pharmacokinetics of Omeprazole in Elderly Subjects

Joo Young Na, Inseung Jeon, Jangsoo Yoon, Yewon Choi, Seo Hyun Yoon, Kyung-Sang Yu, Jae-Yong Chung

Clinical pharmacology in drug development. 2021,Dec;10(12):1469-1477. doi: 10.1002/cpdd.966.
124

Comparative Pharmacokinetics/Pharmacodynamics of Fixed-Dose Combination of Esomeprazole and Calcium Carbonate (AD-206) to the Conventional Esomeprazole

Sungyeun Bae, Jihoon Kwon, Si-Beum Lee, In-Jin Jang, Kyung-Sang Yu, SeungHwan Lee

Drug design, development and therapy. 2021,Dec;Dec 21;15:5099-5108.
125

Clinical development and trial operations in COVID-19 era

Seong Choon Choe

Translational and clinical pharmacology. 2021,Dec;29(4):181-185. doi: 10.12793/tcp.2021.29.e23. Epub 2021 Dec 21.
126

A validated simple LC-MS/MS method for quantifying trimethylamine N-oxide (TMAO) using a surrogate matrix and its clinical application

Yufei Li, Jihyun Kang, Yujin Lee, Jae-Yong Chung, Joo-Youn Cho

Translational and clinical pharmacology. 2021,Dec;29(4):216-225. doi: 10.12793/tcp.2021.29.e19. Epub 2021 Nov 23.
127

Metabolomic Signatures for the Effects of Weight Loss Interventions on Severe Obesity in Children and Adolescents

Min-Ji Sohn, Woori Chae, Jae-Sung Ko, Joo-Youn Cho, Ji-Eun Kim, Ji-Yeob Choi, Han-Byul Jang, Hye-Ja Lee, Sang-Ick Park, Kyung-Hee Park, Peter J van der Spek, Jin-Soo Moon

Metabolites. 2021,Dec;30;12(1):27. doi: 10.3390/metabo12010027.
128

The necessary conduct: Exploratory multiregional clinical trials in East Asia

Inseung Jeon, Yu Kyong Kim, Ildae Song , Deok Yong Yoon, Ki Young Huh, Xuanyou Jin, Kyung-Sang Yu, SeungHwan Lee, Yuji Kumagai, In-Jin Jang

Clinical and translational science. 2021,Nov;14(6):2399-2407. doi: 10.1111/cts.13106.
129

Pharmacokinetics of Ginsenoside Compound K From a Compound K Fermentation Product, CK-30, and From Red Ginseng Extract in Healthy Korean Subjects

Mu Seong Ban, Yun Kim, Sunyoung Lee, ByongYeul Han, Kyung-Sang Yu, In-Jin Jang, Hong Keun Chung, SeungHwan Lee

Clinical pharmacology in drug development. 2021,Nov;2021 Nov;10(11):1358-1364. doi: 10.1002/cpdd.949.
130

Co-Administration of Vonoprazan, Not Tegoprazan, Affects the Pharmacokinetics of Atorvastatin in Healthy Male Subjects.

Sejung Hwang, Jae-Wook Ko, Heechan Lee, Seokuee Kim, Bongtae Kim, Geun Seog Song, Jungryul Kim

Frontiers in pharmacology. 2021,Nov;11;12:754849. doi: 10.3389/fphar.2021.754849. eCollection 2021.
131

Comparative pharmacokinetics of Theracurmin, a highly bioavailable curcumin, in healthy adult subjects

Hyewon Chung, Seo Hyun Yoon, Joo-Youn Cho, Hee Kyung Yeo, Dongseong Shin, Ji-Young Park

International journal of clinical pharmacology and therapeutics. 2021,Oct;59(10):684-690. doi: 10.5414/CP204058.
132

Unraveling the Genomic Architecture of the CYP3A Locus and ADME Genes for Personalized Tacrolimus Dosing

Jihoon G Yoon, Seung Hwan Song, Sungkyoung Choi, Jaeseong Oh, In-Jin Jang, Young Jin Kim, Sanghoon Moon, Bong-Jo Kim, Yuri Cho, Hyo Kee Kim, Sangil Min, Jongwon Ha, Ho Sik Shin 10, Chul Woo Yang, Hye Eun Yoon, Jaeseok Yang, Min Goo Lee, Jae Berm Park, My

Transplantation. 2021,Oct;1;105(10):2213-2225. doi: 10.1097/TP.0000000000003660.
133

Effects of vancomycin-induced gut microbiome alteration on the pharmacodynamics of metformin in healthy male subjects

Eunwoo Kim, Andrew Hyoungjin Kim, Yujin Lee, Sang Chun Ji, Joo-Youn Cho, Kyung-Sang Yu, Jae-Yong Chung

Clinical and translational science 2021,Sep;14(5):1955-1966. doi: 10.1111/cts.13051.
134

Comprehensive analysis of important pharmacogenes in Koreans using the DMET™ platform

Byungwook Kim, Deok Yong Yoon, SeungHwan Lee, In-Jin Jang, Kyung-Sang Yu, Joo-Youn Cho, Jaeseong Oh

Translational and clinical pharmacology. 2021,Sep;29(3):135-149. doi: 10.12793/tcp.2021.29.e14.
135

Effect of CYP3A4 metabolism on sex differences in the pharmacokinetics and pharmacodynamics of zolpidem

Seonghae Yoon, Seongmee Jeong, Eben Jung, Ki Soon Kim, Inseung Jeon, Yujin Lee, Joo-Youn Cho, Woo-Yong Oh, Jae-Yong Chung

Scientific reports. 2021,Sep;27;11(1):19150. doi: 10.1038/s41598-021-98689-z.
136

Prediction of Drug-Drug Interaction Potential of Tegoprazan Using Physiologically Based Pharmacokinetic Modeling and Simulation

Deok Yong Yoon, SeungHwan Lee, In-Jin Jang, Myeongjoong Kim, Heechan Lee, Seokuee Kim, Bongtae Kim, Geun Seog Song, Su-Jin Rhee

Pharmaceutics. 2021,Sep;16;13(9):1489. doi: 10.3390/pharmaceutics13091489.
137

Relationship among genetic polymorphism of SLCO1B1, rifampicin exposure and clinical outcomes in patients with active pulmonary tuberculosis

Eun Sun Kim, Byoung Soo Kwon, Jong Sun Park, Jae-Yong Chung, Soo Hyun Seo, Kyoung Un Park, Junghan Song, Seonghae Yoon, Jae Ho Lee

British journal of clinical pharmacology. 2021,Sep;87(9):3492-3500. doi: 10.1111/bcp.14758.
138

Tissue pharmacokinetics of DHP107, a novel lipid-based oral formulation of paclitaxel, in mice and patients by positron emission tomography

Byung Seok Moon, Hyun Soo Park, Jung Sunwoo, In-Hyun Lee, Anhye Kim, Seol Ju Moon, Heechan Lee, Min Hee Son, Su Bin Kim, Sun Mi Park, Sang-Keun Woo, Jun-Hee Jang, Bom Sahn Kim, Jee Hyun Kim, Sang Eun Kim, Howard Lee

Clinical and translational science. 2021,Sep;14(5):1747-1755. doi: 10.1111/cts.13003.
139

Changes in the gut microbiome influence the hypoglycemic effect of metformin through the altered metabolism of branched-chain and nonessential amino acids

Yujin Lee, Andrew HyoungJin Kim, Eunwoo Kim, SeungHwan Lee, Kyung-Sang Yu, In-Jin Jang, Jae-Yong Chung, Joo-Youn Cho

Diabetes research and clinical practice. 2021,Aug;178:108985. doi: 10.1016/j.diabres.2021.108985.
140

Urine 5-Eicosatetraenoic Acids as Diagnostic Markers for Obstructive Sleep Apnea

Hyun-Woo Shin, Kumsun Cho, Chae-Seo Rhee, Il-Hee Hong, Seok Hyun Cho, Sung Wan Kim, Jiyoung Kim, Daeho So, Joo-Youn Cho, Jong-Wan Park

Antioxidants. 2021,Aug;3;10(8):1242. doi: 10.3390/antiox10081242.
141

Safety, tolerability of ES16001, a novel varicella zoster virus reactivation inhibitor, in healthy adults

Jeon Hwang-Bo, Byungwook Kim, Dae Won Park, Yeong-Geun Le, Jeong Eun Kwon, Jae-Yong Chung, Se Chan Kang

European journal of medical research. 2021,Aug;12;26(1):92. doi: 10.1186/s40001-021-00565-z.
142

A population pharmacokinetic-pharmacodynamic model of YH12852, a highly selective 5-hydroxytryptamine 4 receptor agonist, in healthy subjects and patients with functional constipation

Siun Kim, Hyun A Lee, Seong Bok Jang, Howard Lee

CPT: pharmacometrics & systems pharmacology. 2021,Aug;10(8):902-913. doi: 10.1002/psp4.12664.
143

Pharmacokinetics and pharmacodynamics of tegoprazan co‐administered with amoxicillin and clarithromycin in healthy subjects.

Jong-Lyul Ghim, May Chien Chin, Jinah Jung, Jiwon Lee, Seokuee Kim, Bongtae Kim, Geun Seog Song, Young-Kyung Choi, Jae-Gook Shin

Journal of clinical pharmacology. 2021,Jul;61(7):913-922. doi: 10.1002/jcph.1805. Epub 2021 Jan 12.
144

Pharmacokinetics, Tolerability and Pharmacogenetics of DA-8031 After Multiple Ascending Doses in Healthy Male Subjects

Sejung Hwang, Dae Young Lee, Joo-Youn Cho, Jae-Yong Chung, In-Jin Jang, Kyung-Sang Yu, SeungHwan Lee

Drug design, development and therapy 2021,Jun;1;15:2375-2384. doi: 10.2147/DDDT.S309763. eCollection 2021.
145

Home-based virtual reality for chronic pain: protocol for an NIH-supported randomised-controlled trial

Brandon Birckhead, Sam Eberlein, Genie Alvarez, Rebecca Gale, Taylor Dupuy, Katherine Makaroff, Garth Fuller, Xiaoyu Liu, Kyung-Sang Yu, J T Black, Mariko Ishimori, Swamy Venuturupalli, Joseph Tu, Tom Norris, Mourad Tighiouart, Lindsey Ross, Karma McKelvey, Mark V

BMJ open. 2021,Jun;15;11(6):e050545. doi: 10.1136/bmjopen-2021-050545.
146

Metabolic fingerprinting uncovers the distinction between the phenotypes of tuberculosis-associated COPD and smoking-induced COPD

Da Jung Kim, Jee Youn Oh, Chin Kook Rhee, Seoung Ju Park, Jae Jeong Shim, Joo-Youn Cho

Frontiers in medicine. 2021,May;14;8:619077. doi: 10.3389/fmed.2021.619077.
147

Assessment of Oral Vancomycin-Induced Alterations in Gut Bacterial Microbiota and Metabolome of Healthy Men

Andrew HyoungJin Kim, Yujin Lee, Eunwoo Kim, Sang Chun Ji, Jae-Yong Chung, Joo-Youn Cho

Frontiers in cellular and infection microbiology. 2021,May;27;11:629438. doi: 10.3389/fcimb.2021.629438.
148

Impact of a computerised clinical decision support system on vancomycin loading and the risk of nephrotoxicity

June Young Chun, Kyoung-Ho Song, Dong-Eun Lee, Joo-Hee Hwang, Hyun Gul Jung, Eunjeong Heo, Hyung-Sook Kim, Seonghae Yoon, Jeong Su Park, Pyoeng Gyun Choe, Jae-Yong Chung, Wan Beom Park, Ji Hwan Bang, Hee Hwang, Kyoung-Un Park, Sang Won Park, Nam Joong Kim, Myoung-Do, Eu Suk Kim, Hong Bin Kim

International journal of medical informatics. 2021,May;149:104403. doi: 10.1016/j.ijmedinf.2021.104403.
149

A target-mediated drug disposition population pharmacokinetic model of GC1118, a novel anti-EGFR antibody, in patients with solid tumors

Tae Kyu Chun, Hyun A Lee, Sang-In Park, Do-Youn Oh, Keun-Wook Lee, Jin Won Kim, Jee Hyun Kim, Ahmi Woo, Su Jin Lee, Yung-Jue Bang, Howard Lee

Clinical and translational science. 2021,May;14(3):990-1001. doi: 10.1111/cts.12963.
150

Effect of meal timing on pharmacokinetics and pharmacodynamics of tegoprazan in healthy male volunteers

Deok Y Yoon, Jung Sunwoo, Naree Shin, Ah R Kim, Bongtae Kim, Geun S Song, In-Jin Jang, SeungHwan Lee

Clinical and translational science. 2021,May;14(3):934-941. doi: 10.1111/cts.12958. Epub 2021 Jan 21.
151

A pilot study to investigate the utility of NAT2 genotype-guided isoniazid monotherapy regimens in NAT2 slow acetylators

Hyounggyoon Yoo, Sang Chun Ji, Joo-Youn Cho, Sang-Heon Kim, Jihoon G Yoon, Min Goo Lee, Kyung-Sang Yu, In-Jin Jang, Jaeseong Oh

Pharmacogenet Genomics. 2021,Apr;1;31(3):68-73. doi: 10.1097/FPC.0000000000000423.
152

Safety, pharmacokinetics and pharmacodynamics of BI 655064 in phase 1 clinical trials in healthy Chinese and Japanese subjects

Yasuhiro Tsuda, Christine Grimaldi, Fenglei Huang, Ewald Benediktus, Nobutaka Yagi, Steven J Padula, In-Jin Jang, Jürgen Steffgen

Br J Clin Pharmacol . 2021,Apr; doi: 10.1111/bcp.14601. Online ahead of print.
153

Population Pharmacokinetic Modelling and Simulation to Determine the Optimal Dose of Nanoparticulated Sorafenib to the Reference Sorafenib

Ki Young Huh, Sejung Hwang, Sang Yeob Park, Hye Jung Lim, Miryung Jin, Jaeseong Oh, Kyung Sang Yu, Jae Yong Chung

Pharmaceutics 2021,Apr; 28;13(5):629. doi: 10.3390/pharmaceutics13050629.
154

Comparison of Pharmacokinetic, Pharmacodynamic and Tolerability Profiles of CKD-11101, Darbepoetin Alfa (NESP ®) Biosimilar, to Those of NESP ® After a Single Subcutaneous or Intravenous Administration to Healthy Subjects

Inseung Jeon, Jaeseong Oh, Yu-Kyung Kwon, Seo Hyun Yoon, Joo-Youn Cho, In-Jin Jang, Kyung-Sang Yu, SeungHwan Lee

Drug design, development and therapy. 2021,Apr;28;15:1735-1747. doi: 10.2147/DDDT.S303772. eCollection 2021.
155

Population pharmacokinetic/pharmacodynamic modeling of delayed effect of escitalopram-induced QT prolongation

Yun Kim, Anhye Kim, Jae-Yong Chung

Journal of affective disorders. 2021,Apr;15;285:120-126. doi: 10.1016/j.jad.2021.02.048.
156

YH12852, a Potent and Selective Receptor Agonist of 5-hydroxytryptamine, Increased Gastrointestinal Motility in Healthy Volunteers and Patients With Functional Constipation

Hyun A Lee, Seol Ju Moon, Hyounggyoon Yoo, Mi Kyung Kim, Seong Bok Jang, Seoungoh Lee, Sohee Kim, Howard Lee

Clinical and translational science. 2021,Mar;14(2):625-634. doi: 10.1111/cts.12924.
157

Pharmacokinetic comparison between tablet of varenicline tartrate and orally disintegrating film of varenicline salicylate in healthy subjects

Eunwoo Kim, Jun Gi Hwang, Su Jun Park, Ji Young Han, Young-Sim Choi, Se-Rin Park, Kyung-Sang Yu, Min Kyu Park, SeungHwan Lee

Int J Clin Pharmacol Ther . 2021,Mar;11. doi: 10.5414/CP203953. Online ahead of print.
158

Pharmacokinetics and Safety of Extended-release Ranolazine in Korean and White Healthy Subjects

Hyounggyoon Yoo, Sang Won Lee, Deok Yong Yoon, Seo Hyun Yoon, Joo-Youn Cho, Kyung-Sang Yu, In-Jin Jang, SeungHwan Lee

Clinical therapeutics. 2021,Mar;43(3):526-534.e4. doi: 10.1016/j.clinthera.2021.01.005.
159

Pharmacokinetic Interaction Among Ezetimibe, Rosuvastatin, and Telmisartan

Ki Young Huh, Sang Won Lee, Si Beum Lee, Kyung Tae Kim, In-Jin Jang, SeungHwan Lee

Clinical pharmacology in drug development. 2021,Mar; 1. doi: 10.1002/cpdd.926. Online ahead of print.
160

Pharmacokinetics and tolerability of apremilast in healthy Korean adult males

Ki Young Huh, Yewon Choi, Jim Nissel, Maria Palmisano, Xiaomin Wang, Liangang Liu, Francisco Ramirez-Valle, Howard Lee

Clinical and translational science. 2021,Mar;1. doi: 10.1111/cts.13013. Online ahead of print.
161

Current bioequivalence study designs in South Korea: a comprehensive analysis of bioequivalence study reports between 2013 and 2019

Ki Young Huh, Eunwoo Kim, Soyoung Lee, Hyounggyoon Yoo, Seonghae Yoon, Kyung-Sang Yu, Jae-Yong Chung

Frontiers in pharmacology. 2021,Mar;4;12:651790. doi: 10.3389/fphar.2021.651790. eCollection 2021.
162

Pharmacokinetic comparison between a fixed-dose combination of fimasartan/amlodipine/hydrochlorothiazide 60/10/25 mg and a corresponding loose combination of fimasartan/amlodipine 60/25 mg and hydrochlorothiazide 25 mg in healthy subjects

Jihyun Jung, Soyoung Lee, Jaeseong Oh, SeungHwan Lee, In-Jin Jang, Donghwan Lee, Kyung-Sang Yu

Translational and clinical pharmacology. 2021,Mar;29(1):53-64. doi: 10.12793/tcp.2021.29.e5. Epub 2021 Mar 22.
163

A meta-analysis: efficacy and safety of anti-epileptic drugs prescribed in Korea as monotherapy and adjunctive treatment for patients with focal epilepsy

JuYeun Jeon, Jaeseong Oh, Kyung-Sang Yu

Translational and clinical pharmacology. 2021,Mar;29(1):6-20. doi: 10.12793/tcp.2021.29.e1.
164

Comparative pharmacokinetics between tenofovir disoproxil phosphate and tenofovir disoproxil fumarate in healthy subjects

Sangmi Lee, Eunwoo Kim, Seol Ju Moon, Jina Jung, SeungHwan Lee, Kyung-Sang Yu

Translational and clinical pharmacology. 2021,Mar;29(1):45-52. doi: 10.12793/tcp.2021.29.e4.
165

Population pharmacokinetic model development and its relationship with adverse events of oxcarbazepine in adult patients with epilepsy

Yoonhyuk Jang, Seonghae Yoon, Tae-Joon Kim, SeungHwan Lee, Kyung-Sang Yu, In-Jin Jang, Kon Chu, Sang Kun Lee

Scientific reports. 2021,Mar;18;11(1):6370. doi: 10.1038/s41598-021-85920-0.
166

Effects of perampanel on cognition and quantitative electroencephalography in patients with epilepsy

Seon-Jae Ahn, Tae-Joon Kim, Kwang Su Cha, Jin-Sun Jun, Jung-Ick Byun, Yong-Won Shin, Jun-Sang Sunwoo, SeungHwan Lee, Kyung-Sang Yu, In-Jin Jang, Kon Chu, Sang Kun Lee, Ki-Young Jung

Epilepsy Behav . 2021,Feb;115:107514. doi: 10.1016/j.yebeh.2020.107514. Epub 2020 Dec 14.
167

Tolerability of lacosamide rapid dose titration: A randomized, multicenter, prospective, open-label study

Yong-Won Shin, Jangsup Moon, Yong Won Cho, Dong Wook Kim, Sang Bin Hong, Do-Yong Kim, Hyeyeon Chang, Seo Hyun Yoon, Kyung-Sang Yu, In-Jin Jang, Soon-Tae Lee, Keun-Hwa Jung, Kyung-Il Park, Ki-Young Jung, Manho Kim, Kon Chu, SeungHwan Lee, Sang Kun Lee

Epilepsy Behav . 2021,Feb;115:107663. doi: 10.1016/j.yebeh.2020.107663.
168

Urinary metabolic markers reflect on hepatic, not intestinal, CYP3A activity in healthy subjects

Soyoung Lee, Yujin Lee, Andrew HyoungJin Kim, Sumin Yoon, Jieon Lee, Sang Chun Ji, Seo Hyun Yoon, SeungHwan Lee, Kyung-Sang Yu, In-Jin Jang, Joo-Youn Cho

Drug Metab Pharmacokinet . 2021,Feb;3;36:100374
169

The utility of CYP3A activity endogenous markers for evaluating drug-drug interaction between sildenafil and CYP3A inhibitors in healthy subjects

Soyoung Lee, Andrew HyoungJin Kim, Sumin Yoon, Jieon Lee, Yujin Lee, Sang Chun Ji, Seo Hyun Yoon, SeungHwan Lee, Kyung-Sang Yu, In-Jin Jang, Joo-Youn Cho

Drug Metab Pharmacokinet . 2021,Feb;12;36:100368
170

Comparison of the Pharmacokinetics of a Fixed-Dose Combination of Rosuvastatin/Metformin Sustained-Release (10/1000 mg) and Separate Tablets in Healthy Male Subjects

Ki Young Huh, Eunwoo Kim, Heechan Lee, Inseung Jeon, Hearan Suh, Jongsun Lee, Yunhee Lee, Kyung-Sang Yu, SeungHwan Lee

Clin Pharmacol Drug Dev . 2021,Feb;10(2):207-213. doi: 10.1002/cpdd.841.
171

Pharmacokinetic and Pharmacodynamic Comparison of Two Formulations of a Fixed-Dose Combination of Gemigliptin/Rosuvastatin 50/20 mg: A Randomized, Open-Label, Single-Dose, Two-Way Crossover Study

Eunsol Yang, Hyounggyoon Yoo, In-Jin Jang, Kyung-Sang Yu, SeungHwan Lee

Drug design, development and therapy. 2021,Feb;17;15:651-658. doi: 10.2147/DDDT.S288986. eCollection 2021.
172

Metastasis-on-a-chip reveals adipocyte-derived lipids trigger cancer cell migration via HIF-1α activation in cancer cells

Jieun Seo, Kyeong Seog Kim, Jong-Wan Park, Joo-Youn Cho, Hak Chang, Junji Fukuda, Ki Yong Hong, Yang-Sook Chun

Biomaterials. 2021,Feb;269:120622. doi: 10.1016/j.biomaterials.2020.120622.
173

The potential pathways underlying the association of propyl-paraben exposure with aeroallergen sensitization and EASI score using metabolomics analysis

Yujin Lee, Eun Lee, Dong Keon Yon, Hye Mi Jee, Hey Sung Baek, Seung Won Lee, Joo-Youn Cho, Man Yong Han

Scientific reports. 2021,Feb;12;11(1):3772. doi: 10.1038/s41598-021-83288-9.
174

Pharmacokinetics and Pharmacodynamics of Ursodeoxycholic Acid in an Overweight Population With Abnormal Liver Function

Seonghae Yoon, Heechan Lee, Sang-Chun Ji, Seo Hyun Yoon, Joo-Youn Cho, Jae-Yong Chung

Clin Pharmacol Drug Dev . 2021,Jan;doi: 10.1002/cpdd.790. Online ahead of print.
175

Optimization and validation of a fluorogenic dipeptidyl peptidase 4 enzymatic assay in human plasma

Hyunyee Yoon, Su Hee Cho, Yu Rim Seo, Kyung-Sang Yu, Sung Sup Park, Moon Jung Song

Anal Biochem . 2021,Jan;1;612:113952. doi: 10.1016/j.ab.2020.113952. Epub 2020 Sep 12.
176

An Investigation of the Metabolism and Excretion of KD101 and Its Interindividual Differences: A Microtracing Mass Balance Study in Humans

Anhye Kim, Stephen R. Dueker, Jun Gi Hwang, Jangsoo Yoon, Sang‐Won Lee, Hye Suk Lee, Byung‐Yong Yu, Kyung‐Sang Yu, Howard Lee

Clin Transl Sci . 2021,Jan;14(1):231-238. doi: 10.1111/cts.12848. Epub 2020 Sep 26.
177

Pharmacokinetic equivalence of CT-P17 to high-concentration (100 mg/ml) reference adalimumab: A randomized phase I study in healthy subjects

Kyung-Sang Yu, In-Jin Jang, Hyeong-Seok Lim, Jang Hee Hong, Min-Gul Kim, Min Kyu Park, Doo-Yeoun Cho, Min Soo Park, Jae Yong Chung, Jong-Lyul Ghim, SeungHwan Lee, Seok Kyu Yoon, In Sun Kwon, Sang Joon Lee, Sung Hyun Kim, Yun Ju Bae, Jung Bin Cha, Daniel E Furst

Clin Transl Sci. 2021,Jan;27. doi: 10.1111/cts.12967.
178

Pharmacodynamics and pharmacokinetics of DWP14012 (fexuprazan) in healthy subjects with different ethnicities

Jun Gi Hwang, Inseung Jeon, Sun Ae Park, Areum Lee, Kyung-Sang Yu, In-Jin Jang, SeungHwan Lee

Aliment Pharmacol Ther . 2020,Dec;52(11-12):1648-1657
179

Pharmacodynamics of tegoprazan and revaprazan after single and multiple oral doses in healthy subjects

Jung Sunwoo, Sang Chun Ji, Jaeseong Oh, Mu Seong Ban, Ji Yeon Nam, Bongtae Kim, Geun Seog Song, Kyung-Sang Yu, In-Jin Jang, SeungHwan Lee

Aliment Pharmacol Ther . 2020,Dec;52(11-12):1640-1647
180

Oral absorption of voriconazole is affected by SLCO2B1 c.*396T>C genetic polymorphism in CYP2C19 poor metabolizers

Sang Won Lee, Jaeseong Oh, Andrew HyoungJin Kim, Sang Chun Ji, Sang-In Park 4, Seo Hyun Yoon, Jae-Young Chung, Kyung-Sang Yu, In-Jin Jang, SeungHwan Lee

Pharmacogenomics J . 2020,Dec;20(6):792-800
181

Gut microorganisms and their metabolites modulate the severity of acute colitis in a tryptophan metabolism-dependent manner

Ji-Hee Shin , Young-Kwan Lee, Woo-Jeong Shon, Bora Kim, Che Ok Jeon, Joo-Youn Cho, Herbert C Morse 3rd, Eun Young Choi, Dong-Mi Shin

Eur J Nutr . 2020,Dec;59(8):3591-3601.
182

Electronic medical records-based comparison of glycemic control efficacy between sulfonylureas and dipeptidyl peptidase-4 inhibitors added on to metformin monotherapy in patients with type 2 diabetes

Suhrin Lee , SeungHwan Lee , In-Jin Jang , Kyung-Sang Yu , and Su-jin Rhee

Transl Clin Pharmacol . 2020,Dec;2020 Dec;28(4):199-207. doi: 10.12793/tcp.2020.28.e21. Epub 2020 Dec 18.
183

Effect of meal timing on pharmacokinetics and pharmacodynamics of tegoprazan in healthy male volunteers

Yoon DY, Sunwoo J, Shin N, Kim AR, Kim B, Song GS, Jang IJ, Lee S.

Clin Transl Sci 2020,Dec;2020 Dec 31. doi: 10.1111/cts.12958. Online ahead of print.
184

Pharmacogenomic information from CPIC and DPWG guidelines and its application on drug labels

Yoon DY, Lee S, Ban MS, Jang IJ, Lee S.

Transl Clin Pharmacol 2020,Dec; 2020 Dec;28(4):189-198. doi: 10.12793/tcp.2020.28.e18. Epub 2020 Dec 11.
185

Pharmacokinetic/Pharmacodynamic Interactions Between Evogliptin and Glimepiride in Healthy Male Subjects

Hyounggyoon Yoo, Yun Kim, In-Jin Jang, Kyung-Sang Yu, SeungHwan Lee

Drug Des Devel Ther . 2020,Nov; 24;14:5179-5187
186

Multiple-dose pharmacokinetics and safety of amoxicillin/clavulanate in healthy elderly subjects

Sang Won Lee, Yewon Choi, Kyungho Jang, Seo Hyun Yoon, Jae-Yong Chung

Int J Clin Pharmacol Ther . 2020,Nov;58(11):634-641
187

Population Pharmacokinetic Analysis of Amikacin for Optimal Pharmacotherapy in Korean Patients with Nontuberculous Mycobacterial Pulmonary Disease

Xuanyou Jin, Jaeseong Oh, Joo-Youn Cho, SeungHwan Lee, Su-Jin Rhee

Antibiotics (Basel) . 2020,Nov;6;9(11):784
188

hIL-7-hyFc, A Long-Acting IL-7, Increased Absolute Lymphocyte Count in Healthy Subjects

Sang Won Lee, Donghoon Choi, MinKyu Heo, Eui-Cheol Shin, Su-Hyung Park, So Jeong Kim, Yeon-Kyung Oh, Byung Ha Lee , Se Hwan Yang, Young Chul Sung, Howard Lee

Clinical and translational science. 2020,Nov;2020 Nov;13(6):1161-1169. doi: 10.1111/cts.12800. Epub 2020 May 20.
189

Pharmacokinetic/Pharmacodynamic Interaction Between Evogliptin and Pioglitazone in Healthy Male Subjects

Inyoung Hwang, Yun Kim, Hyounggyoon Yoo, In-Jin Jang, Kyung-Sang Yu, SeungHwan Lee

Drug Des Devel Ther . 2020,Oct;23;14:4493-4502
190

Pharmacokinetics and Tolerability of LC28-0126, a Novel Necrosis Inhibitor, After Multiple Ascending Doses: A Phase I Randomized, Double-blind, Placebo-controlled Study in Healthy Male Subjects

Eunwoo Kim, Inyoung Hwang, SeungHwan Lee, Jaeseong Oh, Hyewon Chung, Myungwon Jin, Soon Ha Kim, Kyung-Sang Yu

Clin Ther . 2020,Oct;42(10):1946-1954.e2
191

Development of a Pharmacokinetic Model Describing Neonatal Fc Receptor-Mediated Recycling of HL2351, a Novel Hybrid Fc-Fused Interleukin-1 Receptor Antagonist, to Optimize Dosage Regimen

Lien Ngo, Jaeseong Oh, Anhye Kim, Hyun-Moon Back, Won-Ho Kang, Jung-Woo Chae, Hwi-Yeol Yun, Howard Lee

CPT Pharmacometrics Syst Pharmacol . 2020,Oct;9(10):584-595
192

The Impact of COVID-19 on the Conduct of Clinical Trials for Medical Products in Korea

JuYeun Jeon, Hyeikyoung Kim, Kyung Sang Yu

J Korean Med Sci . 2020,Sep;14;35(36):e329
193

Phase I clinical trial of KML001 monotherapy in patients with advanced solid tumors.

Seokuee Kim, Sujong Kim, Young Suk Park, Joon Oh Park, Ho Yeong Lim, Jin Seok Ahn, Jeeyun Lee, Jong Mu Sun, Won Ki Kang, RaeO Han, Jungryul Kim, Myung-Ju Ahn

Expert opinion on investigational drugs. 2020,Sep;29(9):1059-1067. doi: 10.1080/13543784.2020.1804855. Epub 2020 Aug 29.
194

Impact of Vancomycin-Induced Changes in the Intestinal Microbiota on the Pharmacokinetics of Simvastatin

Jung Sunwoo, Sang Chun Ji, Andrew HyoungJin Kim, Kyung-Sang Yu, Joo-Youn Cho, In-Jin Jang, SeungHwan Lee

Clin Transl Sci . 2020,Jul;13(4):752-760
195

Usefulness of saliva for perampanel therapeutic drug monitoring

Do-Yong Kim, Jangsup Moon, Yong-Won Shin, Soon-Tae Lee, Keun-Hwa Jung, Kyung-Il Park, Ki-Young Jung, Manho Kim, SeungHwan Lee, Kyung-Sang Yu, In-Jin Jang, KaHeon Song, Kon Chu, Sangkun Lee

Epilepsia . 2020,Jun;61(6):1120-1128
196

Comparative pharmacokinetics of a montelukast/levocetirizine fixed-dose combination chewable tablet versus individual administration of montelukast and levocetirizine after a single oral administration in healthy Korean male subjects

Seol Ju Moon, Kyung-Sang Yu, Jina Jung, Yong-Il Kim, Min-Gul Kim

Int J Clin Pharmacol Ther . 2020,Jun;58(6):354-362.
197

An Assessment of Pharmacokinetic Interaction Between Lobeglitazone and Sitagliptin After Multiple Oral Administrations in Healthy Men

Seol Ju Moon, Kyung-Sang Yu, Min-Gul Kim

Clin Ther . 2020,Jun;42(6):1047-1057
198

Development and validation of a method for the simultaneous quantification of endogenous steroids metabolized by CYP3A

Yujin Lee, Woori Chae, Seonghae Yoon, Jae-Yong Chung, Joo-Youn Cho

Transl Clin Pharmacol . 2020,Jun;28(2):73-82
199

Common data model-based real-world data for practical clinical practice guidelines: clinical pharmacology perspectives

Yoomin Jeon, Yoona Choi, Esther Hehsun Kim, SeonYeong Oh, Howard Lee

Translational and Clinical Pharmacology 2020,Jun;2020 Jun;28(2):67-72. doi: 10.12793/tcp.2020.28.e11. Epub 2020 Jun 25.
200

Pharmacokinetics of human antithrombin III concentrate in the immediate postoperative period after liver transplantation

Bo Rim Kim, Jaeseong Oh, Kyung-Sang Yu, Ho Geol Ryu

Br J Clin Pharmacol . 2020,May;86(5):923-932
201

Comparison of the Pharmacokinetics of Highly Variable Drugs in Healthy Subjects Using a Partial Replicated Crossover Study: A Fixed-Dose Combination of Fimasartan 120 mg and Atorvastatin 40 mg versus Separate Tablets

Jun Gi Hwang, Kyung-Sang Yu, SeungHwan Lee

Drug Des Devel Ther . 2020,May;20;14:1953-1961
202

Author Response: Does the Fc Region Have a Role in the Ocular Half-Life After Intravitreal Injection?

Kwangsic Joo, Yewon Choi, Jae-Yong Chung, Se Joon Woo

Invest Ophthalmol Vis Sci . 2020,May;11;61(5):21
203

Intraocular Distribution and Kinetics of Intravitreally Injected Antibodies and Nanoparticles in Rabbit Eyes

Hyeong Min Kim, Seungmin Ha, Hye Kyoung Hong, Yoonha Hwang, Pilhan Kim 3 4 5, Eunsol Yang 6, Jae Yong Chung 6, Sunyoung Park, Young Joo Park, Kyu Hyung Park, Hyuncheol Kim, Se Joon Woo

Transl Vis Sci Technol . 2020,May;20;9(6):20.
204

External Validation of a Pharmacokinetic Model of Propofol for Target-Controlled Infusion in Children under Two Years Old

Sang Hwan Ji, Ji Hyun Lee, Joo Youn Cho, Hwa Suk Kim, Young Eun Jang, Eun Hee Kim, Jin Tae Kim, Hee Soo Kim

J Korean Med Sci . 2020,May;2020 Mar 23;35(11):e70. doi: 10.3346/jkms.2020.35.e70.
205

Phase 1 study of CWP232291 in patients with relapsed or refractory acute myeloid leukemia and myelodysplastic syndrome

Je-Hwan Lee, Stefan Faderl, John M Page, Chul Won Jung, Sung-Soo Yoon 5, Animesh D Pardanani 6, Pamela S Becker 7, Howard Lee, Jeongeun Choi, Kyoungjune Lee, Minkyoung Kim, Jorge E Cortes

Blood advances. 2020,May;2020 May 12;4(9):2032-2043. doi: 10.1182/bloodadvances.2019000757.
206

Phase I and pharmacokinetic study of the vascular-disrupting agent CKD-516 (NOV120401) in patients with refractory solid tumors

Hark Kyun Kim, Jeong Won Kang, Young-Whan Park, Jung Young Kim, Minchae Kim, Soo Jin Kim, Se-Mi Kim, Keun Ho Ryu, Seonghae Yoon, Yun Kim, Joo-Youn Cho, Keun Seok Lee, Tak Yun, Kiwon Kim, Mi Hyang Kwak, Tae-Sung Kim, Jinsoo Chung, Joong-Won Park

Pharmacol Res Perspect . 2020,Apr;8(2):e00568
207

Mechanism of Chronic Kidney Disease Progression and Novel Biomarkers: A Metabolomic Analysis of Experimental Glomerulonephritis

Kyoung Hee Han, Bora Kim, Sang Chun Ji, Hee Gyung Kang, Hae Il Cheong, Joo-Youn Cho, Il-Soo Ha

Metabolites . 2020,Apr;24;10(4):169
208

A Comprehensive Proteomic and Phosphoproteomic Analysis of Retinal Pigment Epithelium Reveals Multiple Pathway Alterations in Response to the Inflammatory Stimuli

Juha Song, Dohyun Han, Heonyi Lee, Da Jung Kim, Joo-Youn Cho, Jae-Hak Park, Seung Hyeok Seok

Int J Mol Sci . 2020,Apr;25;21(9):3037
209

Comparison of In Vivo Pharmacokinetics and Pharmacodynamics of Vancomycin Products Available in Korea

Hee Kyung Kim, Su Mi Choi, Gaeun Kang, Kyung Hwa Park, Dong Gun Lee 3, Wan Beom Park, Su Jin Rhee, SeungHwan Lee, Sook In Jung, Hee Chang Jang

Yonsei Med J . 2020,Apr;61(4):301-309
210

A Machine Learning-Based Identification of Genes Affecting the Pharmacokinetics of Tacrolimus Using the DMET TM Plus Platform

Jeong-An Gim, Yonghan Kwon, Hyun A Lee, Kyeong-Ryoon Lee, Soohyun Kim, Yoonjung Choi, Yu Kyong Kim, Howard Lee

Int J Mol Sci . 2020,Apr;2020 Apr 4;21(7):2517. doi: 10.3390/ijms21072517.
211

Pharmacokinetic and Safety Profiles of a Fixed‐Dose Combination of Amlodipine, Valsartan, and Atorvastatin: A 3‐Period Replicate Crossover Study.

Seokuee Kim, Jae-Wook Ko, Jung-Ryul Kim

Clinical pharmacology in drug development. 2020,Apr;9(3):386-394. doi: 10.1002/cpdd.727. Epub 2019 Aug 2.
212

The road to biosimilars in rare diseases - ongoing lessons from Gaucher disease

Guillermo Drelichman, Gilberto Castañeda-Hernández, Muhlis Cem Ar, Marta Dragosky, Ricardo Garcia, Howard Lee, Sergey Moiseev, Majid Naderi, Hanna Rosenbaum, Ir Selena Freisens, Pramod K Mistryena Žnidar, Andrés Felipe Zuluaga,

Am J Hematol . 2020,Mar;95(3):233-237
213

Application of an Inter-Species Extrapolation Method for the Prediction of Drug Interactions between Propolis and Duloxetine in Humans

Thi Lien Ngo, Chung-Hee Lee, Nayoung Han, Hyun-Moon Back, Su-Jin Rhee, Keumhan Noh, Hwi-Yeol Yun, Wonku Kang, Jung-Woo Chae

Int J Mol Sci . 2020,Mar; 9;21(5):1862
214

Pharmacokinetics and pharmacodynamics of a fixed-dose combination of gemigliptin/metformin sustained release 25/500 mg compared to the loose combination in healthy male subjects

Xuanyou Jin, Eunwoo Kim, Ki Young Huh, Inyoung Hwang, Joo-Youn Cho, Kyung-Sang Yu, SeungHwan Lee

Transl Clin Pharmacol . 2020,Mar;2020 Mar;28(1):43-54. doi: 10.12793/tcp.2020.28.e2. Epub 2020 Mar 30.
215

Altered Gene Expression Profiles in Peripheral Blood Mononuclear Cells in Obese Subjects

Kyungho Jang, Tao Tong, Jinhui Lee, Taesun Park, Howard Lee

Obesity facts. 2020,Mar;2020;13(3):375-385. doi: 10.1159/000507817. Epub 2020 Jun 16.
216

Intraocular Pharmacokinetics of 10-fold Intravitreal Ranibizumab Injection Dose in Rabbits

Hyeong Min Kim, Young Joo Park , Simin Lee, Joo Young Son, Hye Kyoung Hong, Min Hee Ham, Xuanyou Jin, Jae Yong Chung, Kyu Hyung Park, Ki Dong Park Se Joon Woo

Transl Vis Sci Technol . 2020,Mar;2020 Mar 9;9(4):7. doi: 10.1167/tvst.9.4.7. eCollection 2020 Mar.
217

Complex influences of gut microbiome metabolism on various drug responses

Sihyun Chae, Da Jung Kim, Joo-Youn Cho

Translational and clinical pharmacology. 2020,Mar;28(1):7-16. doi: 10.12793/tcp.2020.28.e3.
218

Comparison of Pharmacokinetics of a Fixed-Dose Combination of Amlodipine/Losartan/Rosuvastatin with Concomitant Administration of Amlodipine/Losartan and Rosuvastatin in Healthy Volunteers.

Yoon DY, Park SI, Jung JA, Kim YI, Jang IJ, Chung JY.

Drug Des Devel Ther. 2020,Feb;19;14:661-668.
219

Colorectal cancer diagnostic model utilizing metagenomic and metabolomic data of stool microbial extracellular vesicles.

Kim DJ, Yang J, Seo H, Lee WH, Ho Lee D, Kym S, Park YS, Kim JG, Jang IJ, Kim YK, Cho JY

Sci Rep 2020,Feb;18;10(1):2860
220

Nicotinamide attenuates the decrease in dendritic spine density in hippocampal primary neurons from 5xFAD mice, an Alzheimer's disease animal model

Hyunju Kim, Bora Kim, Hye-Sun Kim, Joo-Youn Cho

Mol Brain. 2020,Feb;7;13(1):17
221

Safety, tolerability and pharmacokinetics and pharmacodynamics of HL2351, a novel hybrid fc-fused interleukin-1 receptor antagonist, in healthy subjects: A first-in-human study

Jaeseong Oh, Ki Young Huh, Young-Gyu Cho, Ji-Eun Cha, Se-Jin Kim, Seo Hyun Yoon, Sung Sup Park, Hyunyee Yoon, Jieon Lee, Howard Lee

Br J Clin Pharmacol . 2020,Feb;86(2):372-379
222

Pharmacokinetics of high-dose carboplatin in children undergoing high-dose chemotherapy and autologous stem cell transplantation with BSA-based dosing

Che Ry Hong, Hyoung Jin Kang, Seol Ju Moon, Jaeseong Oh, Kyung Taek Hong, Jung Yoon Choi, Kyung-Sang Yu, Hee Young Shin

Bone Marrow Transplant . 2020,Jan;55(1):137-146
223

A Prediction Model for the Intraocular Pharmacokinetics of Intravitreally Injected Drugs Based on Molecular Physicochemical Properties

Hyeong Min Kim, Kyu Hyung Park, Jae Yong Chung, Se Joon Woo

Ophthalmic Res . 2020,Jan;63(1):41-49.
224

Human ADME for YH12852 using wavelength scanning cavity ring-down spectroscopy (WS-CRDS) after a low radioactivity dose

Anhye Kim, Stephen R Dueker, Feng Dong, Ad F Roffel, Sang-Won Lee, Howard Lee

BIOANALYSIS 2020,Jan;2020 Jan;12(2):87-98. doi: 10.4155/bio-2019-0119.
225

Influence of OATP1B1 and BCRP polymorphisms on the pharmacokinetics and pharmacodynamics of rosuvastatin in elderly and young Korean subjects.

Kim Y, Yoon S, Choi Y, Yoon SH, Cho JY, Jang IJ, Yu KS, Chung JY

Sci Rep 2019,Dec;19;9(1):19410.
226

Pharmacokinetic comparison between fixed-dose combination of fimasartan/amlodipine 60/10 mg and the corresponding loose combination through partial replicated crossover study in healthy subjects.

Yang E, Lee S, Lee H, Hwang I, Jang IJ, Yu KS, Lee S

Transl Clin Pharmacol 2019,Dec;27(4):134-140
227

Influence of OATP1B1 and BCRP polymorphisms on the pharmacokinetics and pharmacodynamics of rosuvastatin in elderly and young Korean subjects

Yun Kim, Seonghae Yoon, Yewon Choi, Seo Hyun Yoon, Joo-Youn Cho, In-Jin Jang, Kyung-Sang Yu, Jae-Yong Chung

Scientific reports. 2019,Dec;2019 Dec 19;9(1):19410. doi: 10.1038/s41598-019-55562-4.
228

Pharmacokinetic Interaction Among Telmisartan, Amlodipine, and Hydrochlorothiazide After a Single Oral Administration in Healthy Male Subjects.

Moon SJ, Jeon JY, Yu KS, Kim MG

Clin Ther. 2019,Nov;41(11):2273-2282
229

Author Correction: Ursodeoxycholic acid improves liver function via phenylalanine/tyrosine pathway and microbiome remodelling in patients with liver dysfunction.

Kim DJ, Yoon S, Ji SC, Yang J, Kim YK, Lee S, Yu KS, Jang IJ, Chung JY, Cho JY

Sci Rep. 2019,Nov;13;9(1):17003
230

A Fixed-Dose Combination Of Gemigliptin And Rosuvastatin Exhibits Similar Pharmacokinetics, Pharmacodynamics, And Safety Compared To That Of A Loose Combination In Healthy Subjects.

Kim E, Park KR, Jang IJ, Yu KS, Lee S

Drug Des Devel Ther 2019,Nov;13;13:3879-3885
231

Influence of midazolam-related genetic polymorphism on conscious sedation during upper gastrointestinal endoscopy in a Korean population.

Park JY, Kim BJ, Lee SW, Kang H, Kim JW, Jang IJ, Kim JG

Sci Rep 2019,Nov;5;9(1):16001
232

URC102, a potent and selective inhibitor of hURAT1, reduced serum uric acid in healthy volunteers

Hyun A Lee, Kyung-Sang Yu, Sang-In Park, Seonghae Yoon, Makoto Onohara, Youngjoo Ahn, Howard Lee

Rheumatology. 2019,Nov;2019 Nov 1;58(11):1976-1984. doi: 10.1093/rheumatology/kez140.
233

Effects of Celecoxib on the QTc Interval: A Thorough QT/QTc Study.

Seokuee Kim, Hyeryeon Lee, Jae-Wook Ko, Jung-Ryul Kim

Clinical therapeutics. 2019,Nov;41(11):2204-2218. doi: 10.1016/j.clinthera.2019.09.004. Epub 2019 Sep 26.
234

A safety, pharmacokinetic, pharmacogenomic and population pharmacokinetic analysis of the third-generation EGFR TKI, olmutinib (HM61713), after single oral administration in healthy volunteers.

Young Su Noh, Seonghae Yoon, Suk Ran Kim, Kyung‐Tae Lee, In‐Jin Jang

Basic Clin Pharmacol Toxicol 2019,Oct;125(4):370-381
235

Comprehensive Metabolomic Search for Biomarkers to Differentiate Early Stage Hepatocellular Carcinoma from Cirrhosis.

Kim DJ, Cho EJ, Yu KS, Jang IJ, Yoon JH, Park T, Cho JY

Cancers (Basel) 2019,Oct;6;11(10)
236

ST2 blockade mitigates peritoneal fibrosis induced by TGF-β and high glucose.

Kim YC, Kim KH, Lee S, Jo JW, Park JY, Park MS, Tsogbadrakh B, Lee JP, Lee JW, Kim DK, Oh KH, Jang IJ, Kim YS, Cha RH, Yang SH

J Cell Mol Med 2019,Oct;23(10):6872-6884
237

Indoxyl sulfate-induced TNF-α is regulated by crosstalk between the aryl hydrocarbon receptor, NF-κB, and SOCS2 in human macrophages

Hee Young Kim, Tae-Hyun Yoo, Joo-Youn Cho, Hyeon Chang Kim, Won-Woo Lee

FASEB J . 2019,Oct;2019 Oct;33(10):10844-10858. doi: 10.1096/fj.201900730R. Epub 2019 Jul 5.
238

Development of a physiologically-based pharmacokinetic model for cyclosporine in Asian children with renal impairment.

Yoon S, Yi S, Rhee SJ, Lee HA, Kim Y, Yu KS, Chung JY

Transl Clin Pharmacol. 2019,Sep;27(3):107-114
239

Artificial intelligence in drug development: clinical pharmacologist perspective.

Jang IJ

Transl Clin Pharmacol 2019,Sep;27(3):87-88.
240

Safety, tolerability, and anti-tumor activity of olmutinib in non-small cell lung cancer with T790M mutation: A single arm, open label, phase 1/2 trial.

Kim DW, Lee DH, Han JY, Lee J, Cho BC, Kang JH, Lee KH, Cho EK, Kim JS, Min YJ, Cho JY, An HJ, Kim HG, Lee KH, Kim BS, Jang IJ, Yoon S, Han O, Noh YS, Hong KY, Park K

Lung Cancer 2019,Sep;135:66-72
241

Pharmacokinetics of Ursodeoxycholic Acid in Elderly Volunteers Compared With Younger Adults in a Korean Population.

Lee S, Yoon S, Chung H, Ji SC, Yoon SH, Yu KS, Cho JY, Chung JY

Journal of clinical pharmacology 2019,Aug;59(8):1085-1092.
242

Quantitative prediction of hepatic CYP3A activity using endogenous markers in healthy subjects after administration of CYP3A inhibitors or inducers.

Lee J, Yoon SH, Yi S, Kim AH, Kim B, Lee S, Yu KS, Jang IJ, Cho JY

Drug metabolism and pharmacokinetics 2019,Aug;34(4):247-252
243

Pharmacokinetics and tolerability of IDP-73152 mesylate after a single oral administration under fasted and fed conditions in healthy volunteers.

Shin D, Park SI, Lee HS, An KM, Jung J, Lee M, Yu KS

Drug Des Devel Ther. 2019,Jul; 24;13:2483-2490
244

Pharmacokinetic interactions between telmisartan/amlodipine and rosuvastatin after multiple oral administrations in healthy Korean male subjects.

Moon SJ, Jeon JY, Jang K, Yu KS, Lim Y, Kim MG

Drug Des Devel Ther. 2019,Jul;25;13:2533-2542
245

Use of Molecular Imaging in Clinical Drug Development: a Systematic Review.

Hyeomin Son, Kyungho Jang, Heechan Lee, Sang Eun Kim, Keon Wook kang, Howard lee

Nuclear medicine and molecular imaging 2019,Jun;53(3):208-215.
246

A First-in-Human Phase I Study of GC1118, a Novel Anti-Epidermal Growth Factor Receptor Antibody, in Patients with Advanced Solid Tumors.

"DO-YOUN OH, KEUN-WOOK LEE, SAE-WON HAN, JIN WON KIM, JUNG-WON SHIN, SEONG-JIN JO, JONGHWA WON, SEOKYUNG HAHN, HOWARD LEE, WOO HO KIM, YUNG-JUE BANG"

The oncologist 2019,Jun; pii: theoncologist.2019-0294.
247

Challenges and insights of early oncology drug development in the Asia-Pacific region: introduction of phase I oncology clinical trial center and experience sharing for early clinical trials in Seoul National University Hospital, Korea.

Im SA, Lee DW, Kang R, Kim JH, Kim DW, Jang IJ, Lee JS, Bang YJ

Chin Clin Oncol 2019,Jun;8(3):27
248

Identification of a quadruple mutation that confers tenofovir resistance in chronic hepatitis B patients

Eun-Sook Park, Ah Ram Lee, Doo Hyun Kim, Jeong-Hoon Lee, Jeong-Ju Yoo 3, Sung Hyun Ahn, Heewoo Sim, Soree Park, Hong Seok Kang, Juhee Won, Yea Na Ha 1, Gu-Choul Shin 1, So Young Kwon 4, Yong Kwang Park 5, Byeong-Sun Choi, Yun Bin Lee, Nakcheol Jeong, Yohan An, Young Seok Ju,Su Jong Yu, Hee Bok Ch

J Hepatol . 2019,Jun; 2019 Jun;70(6):1093-1102. doi: 10.1016/j.jhep.2019.02.006. Epub 2019 Feb 20.
249

A Population Pharmacokinetic Study of Prophylactic Fluconazole in Preterm Infants for Prevention of Invasive Candidiasis

Kim YK, Lee J, Oh J, Rhee SJ, Shin SH, Yoon SH, Lee S, Kim HS, Yu KS

Antimicrobial agents and chemotherapy 2019,May;24;63(6).
250

URC102, a potent and selective inhibitor of hURAT1, reduced serum uric acid in healthy volunteers.

Hyun A Lee, Kyung-Sang Yu, Sang-In Park, Seonghae Yoon, Makoto Onohara, Youngjoo Ahn, Howard Lee

Rheumatology. 2019,May; pii: kez140.
251

Comparison of the Plasma Metabolome Profiles Between the Internal Thoracic Artery and Ascending Aorta in Patients Undergoing Coronary Artery Bypass Graft Surgery Using Gas Chromatography Time-of-Flight Mass Spectrometry.

Kim JS, Kim AH, Jang C, Jang IJ, Kim KB, Cho JY, Hwang HY

Journal of Korean medical science 2019,Apr;8;34(13):e104.
252

Factors influencing insulin sensitivity during hyperinsulinemic-euglycemic clamp in healthy Korean male subjects

Dongseong Shin, Young Sil Eom, Suk Chon, Byung-Joon Kim, Kyung-Sang Yu, Dae Ho Lee

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2019,Apr; 10;12:469-476.
253

Development of a Korean-specific virtual population for physiologically based pharmacokinetic modelling and simulation.

Yun Kim Oliver Hatley Su‐jin Rhee Sojeong Yi Hyun A. Lee Sumin Yoon Jae‐Yong Chung Kyung‐Sang Yu Howard Lee

Biopharmaceutics & drug disposition 2019,Apr;40(3-4):135-150.
254

A Rapid Method to Estimate Hepatocyte Loss Due to Drug-Induced Liver Injury.

Chung JY, Longo DM, Watkins PB

Clinical pharmacology and therapeutics 2019,Mar;105(3):746-753.
255

A physiologically-based pharmacokinetic model adequately predicted the human pharmacokinetic profiles of YH4808, a novel K+-competitive acid blocker.

Lee HA, Lee KR, Jang SB, Chung SY, Yu KS, HL

European journal of pharmaceutical sciences 2019,Mar;15;130:1-10.
256

Pharmacokinetics of fludarabine and its association with clinical outcomes in paediatric haematopoietic stem cell transplantation patients

Chung H, Hong KT, Lee JW, Rhee SJ, Kim S, Yoon SH, Yu KS, Kang HJ

Bone Marrow Transplant. 2019,Feb;2019 Feb;54(2):284-292. doi: 10.1038/s41409-018-0260-z. Epub 2018 Jun 18.
257

Pharmacokinetic characteristics and limited sampling strategies for therapeutic drug monitoring of colistin in patients with multidrug-resistant Gram-negative bacterial infections.

Kim EJ, Oh J, Lee K, Yu KS, Chung JY, Hwang JH, Nam EY, Kim HS, Kim M, Park JS, Song KH, Kim ES, Song J, Kim HB

Therapeutic drug monitoring 2019,Feb;41(1):102-106.
258

A Personalized CYP2C19 Phenotype-Guided Dosing Regimen of Voriconazole Using a Population Pharmacokinetic Analysis

Kim Y, Rhee SJ, Park WB, Yu KS, Jang IJ, Lee S

Journal of clinical medicine 2019,Feb;10;8(2).
259

AICAR, an AMPK activator, protects against cisplatin-induced acute kidney injury through the JAK/STAT/SOCS pathway.

Tsogbadrakh B, Ryu H, Ju KD, Lee J, Yun S, Yu KS, Kim HJ, Ahn C, Oh KH

Biochemical and biophysical research communications 2019,Feb;12;509(3):680-686.
260

Pharmacokinetic comparison of gemigliptin 50 mg and metformin 500 mg as a fixed-dose combination and loose combination 

Lee SW, Park SI, Lee S, Chung JY, Yu KS

International journal of clinical pharmacology and therapeutics 2019,Feb;57(2):117-124.
261

Ursodeoxycholic acid exerts hepatoprotective effects by regulating amino acid, flavonoid, and fatty acid metabolic pathways

Da Jung Kim , Hyewon Chung, Sang Chun Ji, SeungHwan Lee,Kyung‑Sang Yu, In‑Jin Jang, Joo‑Youn Cho

Metabolomics Society 2019,Feb;27;15(3):30.
262

Quantification of Thiopurine Nucleotides in Erythrocytes and Clinical Application to Pediatric Acute Lymphoblastic Leukemia

Soo Young Moon, Ji-Hyun Lim, Eun-Hee Kim, Youngwon Nam, Kyung-Sang Yu, Kyung Taek Hong 3 4, Jung Yoon Choi, Che Ry Hong, Hyery Kim, Hyoung Jin Kang, Hee Young Shin, Kyunghoon Lee, Junghan Song, Soo-Youn Lee, Sang Hoon Song

Ther Drug Monit . 2019,Feb;2019 Feb;41(1):75-85. doi: 10.1097/FTD.0000000000000575.
263

. Comparison of the pharmacokinetic-pharmacodynamic relationships of two darbepoetin alfa formulations in healthy male volunteers.

Seokuee Kim, Taegon Hong, Jae-Wook Ko, Wooseong Huh, Jung-Ryul Kim

BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy. 2019,Feb;33(1):101-112. doi: 10.1007/s40259-018-0323-0.
264

What Does it Take to Make Model-Informed Precision Dosing Common Practice? Report from the 1st Asian Symposium on Precision Dosing.

Polasek TM, Rostami-Hodjegan A, Yim DS, Jamei M, Lee H, Kimko H, Kim JK, Nguyen PTT, Darwich AS, Shin JG

The AAPS journal 2019,Jan;9;21(2):17.
265

Effect of cilostazol on the pharmacokinetics of simvastatin in healthy subjects.

Jung-Ryul Kim, Jin Ah Jung, Seokuee Kim, Wooseong Huh, Jong-Lyul Ghim, Jae-Gook Shin, Jae-Wook Ko

BioMed research international. 2019,Jan;9;2019:1365180. doi: 10.1155/2019/1365180. eCollection 2019.
266

OCT3 promoter haplotype is associated with metformin pharmacokinetics in Koreans

Kim EJ, Oh J, Lee K, Yu KS, Chung JY, Hwang JH, Nam EY, Kim HS, Kim M, Park JS, Song KH, Kim ES, Song J, Kim HB

Scientific reports 2018,Nov;16;8(1):16965.
267

Physiologically Based Pharmacokinetic Modeling of Fimasartan, Amlodipine, and Hydrochlorothiazide for the Investigation of Drug-Drug Interaction Potentials

Rhee SJ, Lee HA, Lee S, Kim E, Jeon I, Song IS, Yu KS

Pharmaceutical research. 2018,Oct;15;35(12):236.
268

Assessment of Hepatic Cytochrome P450 3A Activity Using Metabolic Markers in Patients with Renal Impairment.

Kim AH, Yoon S, Lee Y, Lee J, Bae E, Lee H, Kim DK, Lee S, Yu KS, Jang IJ, Cho JY

Journal of Korean medical science 2018,Oct;31;33(53):e298.
269

The Fas Signaling Pathway Is a Common Genetic Risk Factor for Severe Cutaneous Drug Adverse Reactions Across Diverse Drugs

Park HW, Kim SH, Chang YS, Kim SH, Jee YK, Lee AY, Jang IJ, Park HS, Min KU

Allergy Asthma Immunol Res 2018,Sep;10(5):555-561.
270

Lack of a Clinically Significant Pharmacokinetic Interaction Between Pregabalin and Thioctic Acid in Healthy Volunteers

Rhee SJ, Lee H, Ahn LY, Lim KS, Yu KS

Clinical therapeutics 2018,Sep;40(10):1720-1728.e2.
271

Utility of Integrated Analysis of Pharmacogenomics and Pharmacometabolomics in Early Phase Clinical Trial: A Case Study of a New Molecular Entity.

Oh J, Yi S, Gu N, Shin D, Yu KS, Yoon SH, Cho JY, Jang IJ

Genomics & informatics. 2018,Sep;16(3):52-58.
272

Safety and efficacy of fimasartan with essential hypertension patients in real world clinical practice: data from a post marketing surveillance in Korea.

Su-Eun Han, Seung Hee Jeong, Hye Jeong Kang, Myung Sook Hong, Eunah Paek, Hijung Cho, Seong Choon Choe

Translational and clinical pharmacology. 2018,Sep;26(3):118-127. doi: 10.12793/tcp.2018.26.3.118. Epub 2018 Sep 14.
273

Clinical characteristics and satisfaction with the fimasartan in Korean hypertensive patients: a prospective, cross-sectional and open-label, 8-week switching study (Kanarb-hypertension epidemiology medication satisfaction study; K-HEMS study).

Dong Joo Oh, Su-Eun Han, Seung Hee Jeong, Myung Sook Hong, Seong Choon Choe

Clinical hypertension. 2018,Sep;1;24:10. doi: 10.1186/s40885-018-0096-2. eCollection 2018.
274

Comparison of the pharmacokinetics and tolerability of montelukast/levocetirizine administered as a fixed-dose combination and as separate tablets

Seokuee Kim, Jae-Wook Ko, Jung-Ryul Kim

International journal of clinical pharmacology and therapeutics. 2018,Sep;56(9):443-450. doi: 10.5414/CP203265.
275

Regulation of Endogenic Metabolites by Rosuvastatin in Hyperlipidemia Patients: An Integration of Metabolomics and Lipidomics

Lee H, Choi JM, Cho JY, Kim TE, Lee HJ, Jung BH

Chemistry and physics of lipids. 2018,Aug;214:69-83
276

"Ursodeoxycholic acid improves liver function via phenylalanine/ tyrosine pathway and microbiome remodelling in patients with liver dysfunction"

Kim DJ, Yoon S, Ji SC, Yang J, Kim YK, Lee S, Yu KS, Jang IJ, Chung JY, Cho JY

Scientific reports 2018,Aug;8;8(1):11874.
277

A pharmacokinetic drug-drug interaction study between pregabalin and tramadol in healthy volunteers

Lee S, Kim Y, Lee JJ, SIm G, Cho JY, Chung JY,, Yoon S

European journal of clinical pharmacology 2018,Aug; doi: 10.1007/s00228-018-2543-0. [Epub ahead of print]
278

Phloroglucinol ameliorates cognitive impairments by reducing the amyloid β peptide burden and pro-inflammatory cytokines in the hippocampus of 5XFAD mice.

Yang EJ, Mahmood U, Kim H, Choi M, Choi Y, Lee JP, Cho JY, Hyun JW, Kim YS, Chang MJ, Kim HS

Free radical biology and medicine 2018,Aug;126:221-234.
279

"HL156A, a novel pharmacological agent with potent adenosine-monophosphate-activated protein kinase (AMPK) activator activity ameliorates renal fibrosis in a rat unilateral ureteral obstruction model"

Tsogbadrakh B, Ju KD, Lee J, Han M, Koh J, Yu Y, Lee H, Yu KS, Oh YK, Kim HJ, Ahn C, Oh KH

PLoS ONE 2018,Aug;30;13(8):e0201692
280

pharmacokinetic interactions between candesartan and amlodipine following multiple oral administrations in healthy subjects.

Jung-Ryul Kim, Seokuee Kim, Wooseong Huh, Jae-Wook Ko

Drug design, development and therapy. 2018,Aug;10;12:2475-2483. doi: 10.2147/DDDT.S172568. eCollection 2018.
281

pharmacokinetic interactions between candesartan and amlodipine following multiple oral administrations in healthy subjects.

Jung-Ryul Kim, Seokuee Kim, Wooseong Huh, Jae-Wook Ko

Drug design, development and therapy. 2018,Aug;10;12:2475-2483. doi: 10.2147/DDDT.S172568. eCollection 2018.
282

Favorable outcome of post-transplantation cyclophosphamide haploidentical peripheral blood stem cell transplantation with targeted busulfan-based myeloablative conditioning using intensive pharmacokinetic monitoring in pediatric patients.

Hong KT, Kang HJ, Choi JY, Hong CR, Cheon JE, Park JD, Park KD, Song SH, Yu KS, Jang IJ, Shin HY

Biol Blood Marrow Transplant 2018,Jul; pii: S1083-8791(18)30383-5.
283

Safety, tolerability, pharmacodynamics and pharmacokinetics of DWP14012, a novel potassium-competitive acid blocker, in healthy male subjects

Sunwoo J, Oh J, Moon SJ, Ji SC, Lee SH, Yu KS, Kim HS, Lee A, Jang IJ

Aliment. Pharmacol. Ther 2018,Jul;;48(2):206-218.
284

Pharmacokinetic interaction between fimasartan and atorvastatin in healthy male volunteers

Yewon Choi, SeungHwan Lee, In-Jin Jang, Kyung-Sang Yu

Drug Des Devel Ther 2018,Jul;24;12:2301-2309.
285

Effect of food on the pharmacokinetic characteristics of a single oral dose of LCB01-0371, a novel oxazolidinone antibiotic.

Sunwoo J, Kim YK, Choi Y, Yu KS, Nam H, Cho YL, Yoon S, Chung JY.

Drug Des Devel Ther 2018,Jun;11;12:1707-1714.
286

Effect of food on the pharmacokinetics of YH4808, a potassium-competitive acid blocker, after single- and multiple-oral dosing in healthy subjects.

Kim E, Kim A, Yi S, Kim YK, Jang SB, Byun HM, Yoon SH, Cho JY, Jang IJ, Yu KS, Lee S

European journal of clinical pharmacology 2018,Jun;74(10):1261-1272.
287

Identification of ω- or (ω-1)-hydroxylated medium-chain acylcarnitines as novel urinary biomarkers for CYP3A activity.

kim B, Lee J, Shin KH, Lee S, Yu KS, Jang IJ, Cho JY.

Clin Pharmacol Ther 2018,May;2018 May;103(5):879-887. doi: 10.1002/cpt.856. Epub 2017 Oct 10.
288

The safety, tolerability and pharmacokinetics of BI 409306, a novel and potent PDE9 inhibitor: Overview of three Phase I randomised trials in healthy volunteers.

Moschetti V, Kim M, Sand M, Wunderlich G, Andersen G, Feifel U, Jang IJ, Timmer W, Rosenbrock H, Boland K

Eur Neuropsychopharmacol 2018,May;;28(5):643-655.
289

Identification of ω- or (ω-1)-Hydroxylated Medium-Chain Acylcarnitines as Novel Urinary Biomarkers for CYP3A Activity.

Kim B, Lee J, Shin KH, Lee S, Yu KS, Jang IJ, Cho JY.

Clin Pharmacol Ther 2018,May;103(5):879-887.
290

A phase 4 study of nilotinib in Korean patients with Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase: ENESTKorea

Shin J, Koh Y, Yoon SH, Cho JY, Kim DY, Lee KH, Kim HJ, Ahn JS, Kim YK, Park J, Sohn SK, Moon JH, Lee YJ, Yoon S, Lee JO, Cheong JW, Kim KH, Kim SH, Kim HG, Kim H, Nam SH, Do YR, Park SG, Park SK, Bae SH, Song HH, Shin DY, Oh D, Kim MK, Jung CW, Park S, Kim I

Cancer medicine 2018,May;7(5):1814-1823
291

Evaluation of the effects of food on levodropropizine controlled-release tablet and its pharmacokinetic profile in comparison to that of immediate-release tablet.

Lee S, Nam KY, Oh J, Lee S, Cho SM, Choi YW, Cho JY, Lee BJ, Hong JH

Drug Des Devel Ther 2018,May;23;12:1413-1420.
292

Pharmacokinetic characteristics of telaprevir in healthy Korean male subjects and comparisons with Japanese

Choi Y, Yoon S, Matsumoto K, Ohta Y, Lee S, Yu KS, Jang IJ.

Drug Des Devel Ther 2018,Apr;30;12:1045-1051
293

Assessment of induced CYP3A activity in pregnant women using 4β-hydroxycholesterol: Cholesterol ratio as an appropriate metabolic marker

Kim AH, Kim B, Rhee SJ, Lee Y, Park JS, Lee SM, Kim SM, Lee S, Yu KS, Jang IJ, Cho JY

Drug metabolism and pharmacokinetics 2018,Apr;33(3):173-178.
294

Evaluation of drug interactions between fimasartan and rosuvastatin after single and multiple doses in healthy Caucasians

Lee J, Rhee SJ, Lee S, Yu KS

Drug Des Devel Ther 2018,Apr;6;12:787-794.
295

The Genetic Polymorphism UGT1A4*3 Is Associated with Low Posaconazole Plasma Concentrations in Hematological Malignancy Patients Receiving the Oral Suspension.

Suh HJ, Yoon SH, Yu KS, Cho JY, Park SI, Lee E, Lee JO, Koh Y, Song KH, Choe PG, Kim ES, Bang SM, Kim HB, Kim I, Kim NJ, Song SH, Park WB, Oh MD

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 2018,Apr; 26;62(7).
296

Comparison of tadalafil pharmacokinetics after administration of a new orodispersible film versus a film-coated tablet

Park SI, Heo SH, Kim G, Chang S, Song KH, Kim MG, Jin EH, Kim J, Lee S, Hong JH

Drug Des Devel Ther 2018,Apr;20;12:935-942
297

Assessment of Appropriateness of an Initial Dosing Regimen of Vancomycin and Development of a New Dosing Nomogram.

Yoon S, Park KR, Lee S, Song SH, Park WB, Jang IJ, Yu KS.

Basic Clin Pharmacol Toxicol 2018,Feb;2018 Feb;122(2):233-238. doi: 10.1111/bcpt.12873. Epub 2017 Sep 6.
298

Early Therapeutic Drug Monitoring of Posaconazole Oral Suspension in Patients With Hematologic Malignancies.

"Suh HJ, Kim I, Cho JY, Park SI, Yoon SH, Hwang JH, Bae JY, Lee JO, Koh Y, Song KH, Choe PG, Yu KS, Kim ES, Kim HB, Bang SM, Kim NJ, Song SH, Park WB, Oh MD"

Ther Drug Monit 2018,Feb;;40(1):115-119.
299

Assessment of Appropriateness of an Initial Dosing Regimen of Vancomycin and Development of a New Dosing Nomogram.

Yoon S, Park KR, Lee S, Song SH, Park WB, Jang IJ, Yu KS.

Basic Clin Pharmacol Toxicol 2018,Feb;122(2):233-238.
300

Pharmacokinetics and tolerability of eletriptan hydrobromide in healthy Korean subjects.

"Kim YK, Shin KH, Alderman J, Yu KS, Jang IJ, Lee S."

Drug Des Devel Ther 2018,Feb;19;12:331-337.
301

Single-Dose Comparative Pharmacokinetics of Two Formulations of Lenalidomide 25 mg in Healthy Subjects: A Randomized Crossover Study.

Lee S, Hwang JG, Park SY, Lim HJ, Lee SW, Seo MH, Kim J, Hong JH

Advances in therapy 2018,Feb;35(2):210-217.
302

Safety, Tolerability, and Pharmacokinetic Characteristics of a Novel Nonopioid Analgesic, VVZ-149 Injections in Healthy Volunteers: A First-in-Class, First-in-Human Study.

Oh J, Lee S, Kim A, Yoon J, Jang K, Lee DH, Cho S, Lee SR, Yu KS, Chung JY

J Clin Pharmacol 2018,Jan;2018 Jan;58(1):64-73. doi: 10.1002/jcph.973. Epub 2017 Aug 16.
303

S-1-Induced Lacrimal Drainage Obstruction and its Association with Ingredients/Metabolites of S-1 in Tears and Plasma: A Prospective Multi-Institutional Study.

Kim N, Kim JW, Baek JH, Kim JS, Choung HK, Kim TY, Lee KH, Bang YJ, Khwarg SI, Ahn SH, Park DJ, Kim HH, Chung JY, Ahn S, Lee KW.

Cancer Res Treat 2018,Jan;2018 Jan;50(1):30-39. doi: 10.4143/crt.2016.569. Epub 2017 Feb 27.
304

Safety, tolerability and pharmacokinetics of 21 day multiple oral administration of a new oxazolidinone antibiotic, LCB01-0371, in healthy male subjects.

Choi Y, Lee SW, Kim A, Jang K, Nam H, Cho YL, Yu KS, Jang IJ, Chung JY.

J Antimicrob Chemother 2018,Jan;1;73(1):183-190.
305

A non-linear pharmacokinetic-pharmacodynamic relationship of metformin in healthy volunteers: An open-label, parallel group, randomized clinical study.

Chung H, Oh J, Yoon SH, Yu KS, Cho JY, Chung JY

PloS one 2018,Jan;17;13(1):e0191258
306

Safety, Tolerability, and Pharmacokinetic Characteristics of a Novel Nonopioid Analgesic, VVZ-149 Injections in Healthy Volunteers: A First-in-Class, First-in-Human Study.

Oh J, Lee S, Kim A, Yoon J, Jang K, Lee DH, Cho S, Lee SR, Yu KS, Chung JY.

J Clin Pharmacol 2018,Jan;;58(1):64-73.
307

S-1-Induced Lacrimal Drainage Obstruction and Its Association with Ingredients/Metabolites of S-1 in Tears and Plasma: A Prospective Multi-institutional Study.

"Kim N, Kim JW, Baek JH, Kim JS, Choung HK, Kim TY, Lee KH, Bang YJ, Khwarg SI, Ahn SH, Park DJ, Kim HH, Chung JY, Ahn S, Lee KW."

Cancer Res Treat 2018,Jan;50(1):30-39.
308

Early Therapeutic Drug Monitoring of Posaconazole Oral Suspension in Patients with Hematologic Malignancies.

Suh HJ, Kim I, Cho JY, Park SI, Yoon SH, Hwang JH, Bae JY, Lee JO, Koh Y, Song KH, Choe PG, Yu KS, Kim ES, Kim HB, Bang SM, Kim NJ, Oh MD, Song SH, Park WB

Ther Drug Monit 2017,Nov;10.1097/FTD.0000000000000469. [Epub ahead of print]
309

Pharmacokinetics and tolerability of MB12066, a beta-lapachone derivative targeting NAD(P)H: quinone oxidoreductase 1: two independent, double-blind, placebo-controlled, combined single and multiple ascending dose first-in-human clinical trials.

Kim S,Lee S, Cho JY, Yoon SH, Jang IJ, Yu KS,

Drug Des Devel Ther 2017,Nov;7;11:3187-3195.
310

Performance of the Minto model for the target-controlled infusion of remifentanil during cardiopulmonary bypass.

Cho YJ, Jo WY, Oh H, Koo CH, Oh J, Cho JY, Yu KS, Jeon Y, Kim TK

Anaesthesia 2017,Oct;72(10):1196-1205. doi: 10.1111/anae.14019.
311

Comparable pharmacokinetics and pharmacodynamics of two epoetin alfa formulations Eporon® and Eprex® following a single subcutaneous administration in healthy male volunteers.

Yoon S, Rhee SJ, Heo SJ, Oh TY, Yoon SH, Cho JY, Lee S, Yu KS.

Drug Des Devel Ther 2017,Oct;27;11:3127-3135.
312

Failure mode and effects analysis drastically reduced potential risks in clinical trial conduct.

Lee H, Lee H, Baik J, Kim H, Kim R.

Drug Des Devel Ther 2017,Oct;19;11:3035-3043.
313

Pharmacokinetics, Safety, and Tolerability of Tedizolid Phosphate After Single-dose Administration in Healthy Korean Male Subjects.

Kim Y, Kim A, Lee S, Choi SH, Lee DY, Song JS, Lee H, Jang IJ, Yu KS

Clin Ther 2017,Sep;39(9):1849-1857. doi: 10.1016/j.clinthera.2017.08.002. Epub 2017 Aug 31.
314

New tablet formulation of tacrolimus with smaller interindividual variability may become a better treatment option than the conventional capsule formulation in organ transplant patients.

Kim YK, Kim A, Park SJ, Lee H.

Drug Des Devel Ther 2017,Sep;28;11:2861-2869.
315

Integrative Analysis of Renal Ischemia/Reperfusion Injury and Remote Ischemic Preconditioning in Mice.

Cho K, Min SI, Ahn S, Min SK, Ahn C, Yu KS, Jang IJ, Cho JY, Ha J.

J Proteome Res 2017,Aug;16(8):2877-2886. doi: 10.1021/acs.jproteome.7b00167. Epub 2017 Jul 3.
316

Risk factors for suboptimal drug concentration of posaconazole oral suspension in patients with hematologic malignancy.

Kim EJ, Yu KS, Na SH, Nam EY, Oh HS, Kim M, Yoon SH, Lee JO, Koh Y, Song KH, Choe PG, Cho JY, Song SH, Kim ES, Kim HB, Bang SM, Kim NJ, Oh MD, Kim I, Park WB.

J Mycol Med 2017,Aug;pii: S1156-5233(17)30102-6. doi: 10.1016/j.mycmed.2017.08.001. [Epub ahead of print]
317

Role of the Fc Region in the Vitreous Half-Life of Anti-VEGF Drugs.

Joo K, Park SJ, Choi Y, Lee JE,, Na YM, Hong HK, Park KH, Kim HM, Chung JY, Woo SJ

Invest Ophthalmol Vis Sci 2017,Aug;58(10):4261-4267. doi: 10.1167/iovs.17-21813.
318

Correction: GM-CSF Induces Inflammatory Macrophages by Regulating Glycolysis and Lipid Metabolism.

Na YR, Gu GJ, Jung D, Kim YW, Na J, Woo JS, Cho JY, Youn H, Seok SH.

J Immunol 2017,Aug;198(7):3000. doi: 10.4049/jimmunol.1700174.
319

A novel K+ competitive acid blocker, YH4808, sustains inhibition of gastricacid secretion with a faster onset than esomeprazole: randomised clinicalstudy in healthy volunteers.

Yi S, Lee H, Jang SB, Byun HM, Yoon SH, Cho JY, Jang IJ, Yu KS

Alimentary pharmacology & therapeutics. 2017,Aug;46(3):337-346.
320

The Effect of Genetic Polymorphisms in SLCO2B1 on the Lipid-Lowering Efficacy of Rosuvastatin in Healthy Adults with Elevated Low-Density Lipoprotein.

Kim TE, Shin D, Gu N, Jung BH, Kim J, Cho YM, Yu KS, Cho JY.

Basic Clin Pharmacol Toxicol 2017,Jul;121(3):195-201. doi: 10.1111/bcpt.12826. Epub 2017 Jul 10.
321

LBEC0101, A Proposed Etanercept Biosimilar: Pharmacokinetics, Immunogenicity, and Tolerability Profiles Compared with a Reference Biologic Product in Healthy Male Subjects.

Lee H, Chung H, Lee S, Lee H, Yang SM, Yoon SH, Cho JY, Jang IJ, Yu KS.

BioDrugs 2017,Jul;doi: 10.1007/s40259-017-0230-9. [Epub ahead of print]
322

Pediatric patients undergoing hematopoietic stem cell transplantation can greatly benefit from a novel once-daily intravenous busulfan dosing nomogram.

Rhee SJ, Lee JW, Yu KS, Hong KT, Choi JY, Hong CR, Park KD, Shin HY, Song SH, Kang HJ, Lee H

Am. J. Hematol. 2017,Jul;92(7):607-613. doi: 10.1002/ajh.24734. Epub 2017 May 30.
323

Pantoprazole Does Not Reduce the Antiplatelet Effect of Clopidogrel: A Randomized Controlled Trial in Korea.

Choi YJ, Kim N, Jang IJ, Cho JY, Nam RH, Park JH, Jo HJ, Yoon H, Shin CM, Park YS, Lee DH, Jung HC

Gut Liver 2017,Jul;11(4):504-511. doi: 10.5009/gnl16352.
324

Plasma LTE4/PGF2α Ratio and Blood Eosinophil Count Are Increased in Elderly Asthmatics With Previous Asthma Exacerbation.

Ban GY, Ye YM, Kim SH, Hur GY, Kim JH, Shim JJ, Cho K, Cho JY, Park HS; PRANA group.

Allergy Asthma Immunol Res 2017,Jul;9(4):378-382. doi: 10.4168/aair.2017.9.4.378.
325

Distribution of Exogenous and Endogenous CYP3A Markers and Related Factors in Healthy Males and Females.

Lee J, Kim AH, Yi S, Lee S, Yoon SH, Yu KS, Jang IJ, Cho JY

AAPS J 2017,Jul;19(4):1196-1204. doi: 10.1208/s12248-017-0090-8. Epub 2017 May 18.
326

Prediction of serum theophylline concentrations and CYP1A2 activity by analyzing urinary metabolites in preterm infants

Sohn JA, Kim HS, Oh J, Cho JY, Yu KS, Lee J, Shin SH, Lee JA, Choi CW, Kim EK, Kim BI, Park EA.

Br J Clin Pharmacol 2017,Jun;83(6):1279-1286. doi: 10.1111/bcp.13211. Epub 2017 Jan 18.
327

Comparison of Plasma Concentrations of Posaconazole with the Oral Suspension and Tablet in Korean Patients with Hematologic Malignancies.

Suh HJ, Kim I, Cho JY, Park SI, Yoon SH, Lee JO, Koh Y, Song KH, Choe PG, Yu KS, Kim ES, Kim HB, Bang SM, Kim NJ, Song SH, Park WB, Oh MD

Infect Chemother 2017,Jun;49(2):135-139. doi: 10.3947/ic.2017.49.2.135. Epub 2017 Jun 9.
328

A Significant Influence of Metronidazole on Busulfan Pharmacokinetics: A Case Report of Therapeutic Drug Monitoring.

Chung H, Yu KS, Hong KT, Choi JY, Hong CR, Kang HJ, Park KD, Shin HY, Lee S.

Ther Drug Monit 2017,Jun;39(3):208-210. doi: 10.1097/FTD.0000000000000395.
329

High-Fat Diet and Voluntary Chronic Aerobic Exercise Recover Altered Levels of Aging-Related Tryptophan Metabolites along the Kynurenine Pathway.

Lee KJ, Jung KH, Cho JY, Lee ST, Kim HS, Shim JH, Lee SK, Kim M, Chu K

Exp Neurobiol 2017,Jun;26(3):132-140. doi: 10.5607/en.2017.26.3.132. Epub 2017 Jun 26.
330

Indoxyl sulfate (IS)-mediated immune dysfunction provokes endothelial damage in patients with end-stage renal disease (ESRD).

Kim HY, Yoo TH, Hwang Y, Lee GH, Kim B, Jang J, Yu HT, Kim MC, Cho JY, Lee CJ, Kim HC, Park S, Lee WW

Sci Rep 2017,Jun;7(1):3057. doi: 10.1038/s41598-017-03130-z.
331

Pharmacokinetic comparison using two tablets of an evogliptin/metformin XR 2.5/500 mg fixed dose combination vs. 1 tablet each of evogliptin 5 mg and metformin XR 1,000 mg .

Yoon S, Rhee SJ, Park SI, Yoon SH, Cho JY, Jang IJ, Lee S, Yu KS.

Int J Clin Pharmacol Ther 2017,Jun;55(6):533-539. doi: 10.5414/CP202930.
332

Pharmacokinetics and Safety of a Single Dose of the Novel Necrosis Inhibitor LC28-0126 in Healthy Male Subjects

Seokuee Kim, Hyewon Chung, SeungHwan Lee, Sang-Heon Cho, Hyun-Jai Cho, Soon Ha Kim, In-Jin Jang, Kyung-Sang Yu

Br J Clin Pharmacol 2017,Jun;83(6):1205-1215. doi: 10.1111/bcp.13213. Epub 2017 Jan 25.
333

Korean Variant Archive (KOVA): a reference database of genetic variations in the Korean population.

Lee S, Seo J, Park J, Nam JY, Choi A, Ignatius JS, Bjornson RD, Chae JH, Jang IJ, Lee S, Park WY, Baek D, Choi M

Sci Rep 2017,Jun;7(1):4287. doi: 10.1038/s41598-017-04642-4.
334

Effects of dexamethasone coadministered with oseltamivir on the pharmacokinetics of oseltamivir in healthy volunteers

Jang K, Kim M, Oh J, Lee S, Cho J, Yu K, Choi T, Lee S, Lim K,

Drug Design, Development and Therapy 2017,May;11:705-711. doi: 10.2147/DDDT.S124307. eCollection 2017.
335

Pharmacometabolomics for predicting variable busulfan exposure in paediatric haematopoietic stem cell transplantation patients.

Kim B, Lee JW, Hong KT, Yu KS, Jang IJ, Park KD, Shin HY, Ahn HS, Cho JY, Kang HJ.

Sci Rep 2017,May;7(1):1711. doi: 10.1038/s41598-017-01861-7.
336

Exploration of Biomarkers for Amoxicillin/Clavulanate-Induced Liver Injury: Multi-Omics Approaches.

Lee J, Ji SC, Kim B, Yi S, Shin KH, Cho JY, Lim KS, Lee SH, Yoon SH, Chung JY, Yu KS, Park HS, Kim SH, Jang IJ

Clin Transl Sci 2017,May;10(3):163-171. doi: 10.1111/cts.12425. Epub 2016 Oct 26.
337

Characterization of ADME gene variation in 21 populations by exome sequencing.

Hovelson DH, Xue Z, Zawistowski M, Ehm MG, Harris EC, Stocker SL, Gross AS, Jang IJ, Ieiri I, Lee JE, Cardon LR, Chissoe SL, Abecasis G, Nelson MR

Pharmacogenet Genomics 2017,May;27(3):89-100. doi: 10.1097/FPC.0000000000000260.
338

Physiologically Based Pharmacokinetic Modelling and Prediction of Metformin Pharmacokinetics in Renal/Hepatic-Impaired Young Adults and Elderly Populations.

Rhee SJ, Chung H, Yi S, Yu KS, Chung JY.

Eur J Drug Metab Pharmacokinet 2017,May;doi: 10.1007/s13318-017-0418-x. [Epub ahead of print]
339

Pharmacokinetics and tolerability of DA-8031, a novel selective serotonin reuptake inhibitor for premature ejaculation in healthy male subjects.

Shin D, Lee S, Yi S, Yoon SH, Cho JY, Bahng MY, Jang IJ, Yu KS

Drug Des Devel Ther 2017,May;11:713-723. doi: 10.2147/DDDT.S126861. eCollection 2017.
340

Pharmacokinetics and Tolerance of the Phage Endolysin-Based Candidate Drug SAL200 after a Single Intravenous Administration among Healthy Volunteers.

Jun SY, Jang IJ, Yoon S, Jang K, Yu KS, Cho JY, Seong MW, Jung GM, Yoon SJ, Kang SH.

Antimicrob Agents Chemother 2017,May;61(6). pii: e02629-16. doi: 10.1128/AAC.02629-16. Print 2017 Jun.
341

Effects of CYP2C19 Genetic Polymorphisms on PK/PD Responses of Omeprazole in Korean Healthy Volunteers.

Park S, Hyun YJ, Kim YR, Lee JH, Ryu S, Kim JM, Oh WY, Na HS, Lee JG, Seo DW, Hwang IY, Park Z, Jang IJ, Oh J, Choi SE

J Korean Med Sci 2017,May;32(5):729-736. doi: 10.3346/jkms.2017.32.5.729.
342

A randomized, double-blind, single-dose, two-arm, parallel study comparing pharmacokinetics, immunogenicity and tolerability of branded adalimumab and its biosimilar LBAL in healthy male volunteers.

Park KR, Chung H, Yang SM, Lee S, Yoon SH, Cho JY, Jang IJ, Yu KS

Expert Opin Investig Drugs 2017,May;26(5):619-624. doi: 10.1080/13543784.2017.1307339. Epub 2017 Mar 23.
343

A pharmacogenomic study on the pharmacokinetics of tacrolimus in healthy subjects using the DMET TM Plus platform

Y Choi, F Jiang, H An, H J Park, J H Choi, H Lee

Pharmacogenomics J . 2017,May;2017 Mar;17(2):174-179.
344

The novel carboxylesterase 1 variant c.662A>G may decrease the bioactivation of oseltamivir in humans.

Oh J, Lee S, Lee H, Cho JY, Yoon SH, Jang IJ, Yu KS, Lim KS

PLoS ONE 2017,Apr;12(4):e0176320. doi: 10.1371/journal.pone.0176320. eCollection 2017.
345

A first-in-human, double-blind, placebo-controlled, randomized, dose escalation study of DWP05195, a novel TRPV1 antagonist, in healthy volunteers.

Lee J, Kim BH, Yu KS, Kim HS, Kim JD, Cho JY, Lee S, Gu N.

Drug Des Devel Ther. 2017,Apr;11:1301-1313. doi: 10.2147/DDDT.S128727. eCollection 2017.
346

Targeted next-generation sequencing for comprehensive genetic profiling of pharmacogenes.

Han SM, Park J, Lee JH, Lee SS, Kim H, Han H, Kim Y, Yi S, Cho JY, Jang IJ, Lee MG

Clin Pharmacol Ther 2017,Mar;101(3):396-405
347

A comparative pharmacokinetic and tolerability analysis of the novel orotic acid salt form of tenofovir disoproxil and the fumaric acid salt form in healthy subjects.

Kim YK, Choi MJ, Oh TY, Yu KS, Lee S

Drug Des Devel Ther 2017,Mar;10;11:713-723.
348

Pharmacokinetic comparison and bioequivalence evaluation of two 10-mg baclofen formulations in healthy male subjects .

Yoon S, Lee S, Yu KS, Yim SV, Kim BH.

Int J Clin Pharmacol Ther 2017,Feb;55(2):194-200. doi: 10.5414/CP202760.
349

Effects of renal impairment on the pharmacokinetics and pharmacodynamics of a novel DPP-IV inhibitor, evogliptin (DA-1229).

Oh J, Kim AH, Lee S, Cho H, Kim YS, Bahng MY, Yoon SH, Cho JY, Jang IJ, Yu KS

Diabetes Obes Metab 2017,Feb;19(2):294-298. doi: 10.1111/dom.12813. Epub 2016 Nov 24.
350

Population pharmacokinetics and dose-response relationship of levetiracetam in adult patients with epilepsy.

Rhee SJ, Shin JW, Lee S, Moon J, Kim TJ, Jung KY, Park KI, Lee ST, Jung KH, Yu KS, Jang IJ, Chu K, Lee SK.

Epilepsy Res. 2017,Feb;132:8-14. doi: 10.1016/j.eplepsyres.2017.02.011. Epub 2017 Feb 27.
351

Changes in Cardiac Function After a Single Intravenous Administration of CKD-712 in Healthy Male Volunteers.

Park SI, Kim J, Yu KS, Jang IJ, Lee S.

Clin Drug Investig 2017,Feb;37(4):393-403. doi: 10.1007/s40261-017-0494-3.
352

An accelerator mass spectrometry-enabled microtracer study to evaluate the first-pass effect on the absorption of YH4808.

Kim A, Yu BY, Dueker SR, Shin KH, Kim HS, Ahn H, Cho JY, Yu KS, Jang IJ, Lee H

Clin Pharmacol Ther 2017,Feb;102(3):537-546. doi: 10.1002/cpt.672. Epub 2017 May 26.
353

Bioequivalence of two formulations of pregabalin 150-mg capsules under fasting conditions in healthy male subjects .

Lee HA, Lee S, Yim SV, Kim BH.

Int J Clin Pharmacol Ther 2017,Feb;55(2):171-176.
354

Pharmacokinetics and effect on the corrected QT interval of single-dose escitalopram in healthy elderly compared with younger adults.

Chung H, Kim A, Lim KS, Park SI, Yu KS, Yoon SH, Cho JY, Chung JY.

Int Clin Psychopharmacol 2017,Jan;32(1):20-26.
355

Pharmacokinetic comparison of two formulations of talniflumate 370 mg tablets in healthy Korean volunteers 

Kim Y, Yim S, Kim BH, Lee S.

Int J Clin Pharmacol Ther 2017,Jan;55(1):102-108. doi: 10.5414/CP202707.
356

Metabolomic analysis identifies potential diagnostic biomarkers for aspirin-exacerbated respiratory disease.

Ban GY, Cho K, Kim SH, Yoon MK, Kim JH, Lee HY, Shin Y, Ye YM, Cho JY, Park HS

Clin. Exp. Allergy 2017,Jan;47(1):37-47.
357

Combined untargeted and targeted metabolomic profiling reveals urinary biomarkers for discriminating obese from normal-weight adolescents.

Cho K, Moon JS, Kang JH, Jang HB, Lee HJ, Park SI, Yu KS, Cho JY.

Pediatr Obes 2017,Jan;12(2):93-101.
358

Pharmacokinetic characteristics of fluticasone, salmeterol and tiotropium after concurrent inhalation

선우정, 이수진, 이승환, 이상원, 정진아, 손한길, 장인진

Translational and Clinical Pharmacology 2017,Jan;2017, vol.25, no.2, pp. 85-92 (8 pages)
359

Comparative pharmacokinetic and bioequivalence evaluation of two formulations of morniflumate 350-mg tablets in healthy male subjects

Heechan Lee, Sung-Vin Yim, Bo-Hyung Kim, SeungHwan Lee

International journal of clinical pharmacology and therapeutics. 2017,Jan;Int J Clin Pharmacol Ther. 2017 Jan;55(1):95-101
360

Determination of the starting dose in the first-in-human clinical trials with monoclonal antibodies: a systematic review of papers published between 1990 and 2013.

Suh HY, Peck CC, Yu KS, Lee H

Drug Des Devel Ther 2016,Dec;10:4005-4016. eCollection 2016.
361

Pharmacokinetics and Safety of a Single Dose of the Novel Necrosis Inhibitor LC28-0126 in Healthy Male Subjects

Kim S, Chung H, Lee SH, Cho SH, Cho HJ, Kim SH, Jang IJ, Yu KS.

Br J Clin Pharmacol 2016,Dec;83(6):1205-1215. doi: 10.1111/bcp.13213. Epub 2017 Jan 25.
362

Prediction of serum theophylline concentrations and CYP1A2 activity by analyzing urinary metabolites in preterm infants

Sohn JA, Kim HS, Oh J, Cho JY, Yu KS, Lee J, Shin SH, Lee JA, Choi CW, Kim EK, Kim BI, Park EA.

Br J Clin Pharmacol 2016,Dec;;83(6):1279-1286. doi: 10.1111/bcp.13211. Epub 2017 Jan 18.
363

Characterization of ADME gene variation in 21 populations by exome sequencing.

Hovelson DH1, Xue Z, Zawistowski M, Ehm MG, Harris EC, Stocker SL, Gross AS, Jang IJ, Ieiri I, Lee JE, Cardon LR, Chissoe SL, Abecasis G, Nelson MR

Pharmacogenet Genomics 2016,Dec;(3):89-100. doi: 10.1097/FPC.0000000000000260.
364

HLA-B*40:02 and DRB1*04:03 are risk factors for oxcarbazepine-induced maculopapular eruption.

Moon J,, Kim TJ, Lim JA, Sunwoo JS, Byun JI, Lee ST, Jung KH, Park KI, Jung KY, Jeon D, Yu KS, Jang IJ, Chu K, Lee SK

Epilepsia. 2016,Nov;57(11):1879-1886. doi: 10.1111/epi.13566. Epub 2016 Sep 26.
365

A bioequivalence study of two omeprazole formulations in healthy male volunteers.

Kim YK, Yoon S, Yu KS, Kim BH, Yim SV.

Int J Clin Pharmacol Ther 2016,Nov;54(11):928-934.
366

Targeted busulfan and fludarabine-based conditioning for bone marrow transplantation in chronic granulomatous disease.

Ju HY, Kang HJ, Hong CR, Lee JW, Kim H, Song SH, Yu KS, Jang IJ, Park JD, Park KD, Shin HY, Kim JG, Ahn HS

Korean journal of pediatrics. 2016,Nov;6:36599. doi: 10.1038/srep36599.
367

Exploration of the Sphingolipid Metabolite, Sphingosine-1-phosphate and Sphingosine, as Novel Biomarkers for Aspirin-exacerbated Respiratory Disease.

Trinh HK, Kim SC, Cho K, Kim SJ, Ban GY, Yoo HJ, Cho JY, Park HS, Kim SH

Sci Rep 2016,Nov;6:36599. doi: 10.1038/srep36599.
368

GM-CSF Induces Inflammatory Macrophages by Regulating Glycolysis and Lipid Metabolism.

Na YR, Gu GJ, Jung D, Kim YW, Na J, Woo JS, Cho JY, Youn H, Seok SH

Journal of immunology 2016,Nov;197(10):4101-4109. Epub 2016 Oct 14.
369

The pharmacokinetic comparison and bioequivalence evaluation of two 10-mg baclofen formulations in healthy male subjects .

Yoon S, Lee S, Yu KS, Yim SV, Kim BH.

Int J Clin Pharmacol Ther 2016,Nov;55(2):194-200. doi: 10.5414/CP202760.
370

Targeted next-generation sequencing for comprehensive genetic profiling of pharmacogenes.

Han SM, Park J, Lee JH, Lee SS, Kim H, Han H, Kim Y, Yi S, Cho JY, Jang IJ, Lee MG

Clin Pharmacol Ther 2016,Oct;101(3):396-405. doi: 10.1002/cpt.532. Epub 2016 Nov 24.
371

Exploration of Biomarkers for Amoxicillin/Clavulanate-Induced Liver Injury: Multi-Omics Approaches.

Lee J, Ji SC, Kim B, Yi S, Shin KH, Cho JY, Lim KS, Lee SH, Yoon SH, Chung JY, Yu KS, Park HS, Kim SH, Jang IJ

Clin Transl Sci 2016,Oct;10(3):163-171. doi: 10.1111/cts.12425. Epub 2016 Oct 26.
372

Pharmacokinetics and effect on the corrected QT interval of single-dose escitalopram in healthy elderly compared with younger adults.

Chung H, Kim A, Lim KS, Park SI, Yu KS, Yoon SH, Cho JY, Chung JY.

Int Clin Psychopharmacol 2016,Oct;32(1):20-26.
373

Urinary 6β-Hydroxycortisol/Cortisol Ratio Most Highly Correlates WithMidazolam Clearance Under Hepatic CYP3A Inhibition and Inductionin Females: A Pharmacometabolomics Approach

Kwang-Hee Shin, Li Young Ahn, Man Ho Choi, Ju-Yeon Moon, Jieon Lee, In-Jin Jang, Kyung-Sang Yu, Joo-Youn Cho

The AAPS Journal 2016,Sep;1254-61. doi: 10.1208/s12248-016-9941-y. Epub 2016 Jun 17.
374

Comparisons of the pharmacokinetics and tolerability of fixed-dose combinations of amlodipine besylate/losartan and amlodipine camsylate/losartan in healthy subjects: a randomized, open-label, single-dose, two-period, two-sequence crossover study.

Choi Y, Lee S, Cho SM, Kang WH, Nam KY, Jang IJ, Yu KS

Drug Des Devel Ther 2016,Sep;10:3021-3028. eCollection 2016.
375

Pharmacokinetics, Safety, and Tolerability of Metformin in Healthy Elderly Subjects.

Jang K, Chung H, Yoon JS, Moon SJ, Yoon SH, Yu KS, Kim K, Chung JY

J Clin Pharmacol 2016,Sep;56(9):1104-10. doi: 10.1002/jcph.699. Epub 2016 Feb 22.
376

Comparison of R(+)-α-lipoic acid exposure after R(+)-α-lipoic acid 200 mg and 300 mg and thioctic acid 600 mg in healthy Korean male subjects

윤장수, 문설주, 이광옥, 윤서현, 장인진, 유경상, 이승환

TCP 2016,Sep;24(3):137-142
377

Therapeutic drug monitoring of vancomycin in a patient with Duchenne muscular dystrophy (DMD): A case report

이상원, 윤성혜, 유경상, 이승환

TCP 2016,Sep;24(3):124-126
378

Population pharmacokinetic analysis to recommend the optimal dose of udenafil in patients with mild and moderate hepatic impairment.

Kim A, Lee J, Shin D, Jung YJ, Bahng MY, Cho JY, Jang IJ

Br J Clin Pharmacol 2016,Aug;82(2):389-98. doi: 10.1111/bcp.12977. Epub 2016 Jun 3.
379

Pharmacokinetic and pharmacodynamic interactions between metformin and a novel dipeptidyl peptidase-4 inhibitor, evogliptin, in healthy subjects.

Rhee SJ, Choi Y, Lee S, Oh J, Kim SJ, Yoon SH, Cho JY, Yu KS

Drug Des Devel Ther 2016,Aug;10:2525-34. doi: 10.2147/DDDT.S110712. eCollection 2016.
380

An analysis of QTc prolongation with atypical antipsychotic medications and selective serotonin reuptake inhibitors using a large ECG record database.

Park SI, An H, Kim A, Jang IJ, Yu KS, Chung JY.

Expert Opin Drug Saf 2016,Aug;15(8):1013-9. doi: 10.1080/14740338.2016.1199681. Epub 2016 Jun 22.
381

Metabolomic analysis identifies potential diagnostic biomarkers for aspirin-exacerbated respiratory disease.

Ban GY, Cho K, Kim SH, Yoon MK, Kim JH, Lee HY, Shin Y, Ye YM, Cho JY, Park HS

Clin. Exp. Allergy 2016,Aug;47(1):37-47. doi: 10.1111/cea.12797. Epub 2016 Sep 27.
382

Use of Rabbit Eyes in Pharmacokinetic Studies of Intraocular Drugs.

Ahn SJ, Hong HK, Na YM, Park SJ, Ahn J, Oh J, Chung JY, Park KH, Woo SJ

Journal of visualized experiments 2016,Jul;(113). doi: 10.3791/53878.
383

Effectiveness of increasing the frequency of posaconazole syrup administration to achieve optimal plasma concentrations in patients with haematological malignancy.

cho K, Moon JS, Kang JH, Jang HB, Lee HJ, Park SI, Yu KS, Cho JY.

Int J Antimicrob Agents 2016,Jul;48(1):106-10. doi: 10.1016/j.ijantimicag.2016.04.013. Epub 2016 May 12.
384

Absence of ethnic differences in the pharmacokinetics of moxifloxacin, simvastatin, and meloxicam among three East Asian populations and Caucasians.

Hasunuma T, Tohkin M, Kaniwa N, Jang IJ, Yimin C, Kaneko M, Saito Y, Takeuchi M, Watanabe H,Yamazoe Y, Uyama Y, Kawai

Br J Clin Pharmacol 2016,Jun;81(6):1078-90. doi: 10.1111/bcp.12884. Epub 2016 Mar 14.
385

A thorough QT study to evaluate the QTc prolongation potential of two neuropsychiatric drugs, quetiapine and escitalopram, in healthy volunteers

Kim A, Lim KS, Lee H, Chung H, Yoon SH, Yu KS, Cho JY, Jang IJ, Chung JY.

Int Clin Psychopharmacol 2016,Jun;31(4):210-7. doi: 10.1097/YIC.0000000000000124.
386

Pharmacokinetics and bioequivalence of two different 20 mg olmesartan tablets: A randomized, single-dose, two-period crossover study in healthy Korean male volunteers

이지언, 김언혜, 유경상, 정재용, 임성빈, 김보형

TCP 2016,Jun;24(2):111
387

Pharmacokinetic comparison of two levofloxacin 100-mg tablet formulations and determination of time point appropriately reflecting its area under the curve

박경윤, 장경호, 이승환, 유경상, 김보형, 임성빈

TCP 2016,Jun;24(2):84-89
388

Evaluation of factors associated with drug-induced liver injury using electronic medical records

정혜원, 안형미, 이지은, 오재성, 유경상, 정재용

TCP 2016,Jun;24(2):78-83
389

Intraocular Pharmacokinetics of Intravitreal Aflibercept (Eylea) in a Rabbit Model.

Park SJ, Choi Y, Na YM, Hong HK, Park JY, Park KH, Chung JY, Woo SJ

Invest Ophthalmol Vis Sci 2016,May;1;57(6):2612-7. doi: 10.1167/iovs.16-19204.
390

Factors influencing topiramate clearance in adult patients with epilepsy: A population pharmacokinetic analysis.

Bae EK, Lee J, Shin JW, Moon J, Lee KJ, Shin YW, Kim TJ, Shin D, Jang IJ, Lee SK

Seizure 2016,Apr;37:8-12. doi: 10.1016/j.seizure.2016.02.002. Epub 2016 Feb 11.
391

Monitoring the Intracellular Tacrolimus Concentration in Kidney Transplant Recipients with Stable Graft Function

"Seung Seok Han, Seung Hee Yang, Min Chang Kim, Joo-Youn Cho, Sang-Il Min, Jung Pyo Lee, Dong Ki Kim

PLoS One 2016,Apr;11(4):e0153491. doi: 10.1371/journal.pone.0153491. eCollection 2016.
392

The MATE1 rs2289669 polymorphism affects the renal clearance of metformin following ranitidine treatment.

Cho SK, Chung JY.

Cho SK, Chung JY. 2016,Apr;54(4):253-62. doi: 10.5414/CP202473.
393

The influence of dietary sodium content on the pharmacokinetics and pharmacodynamics of fimasartan

Namyi Gu, Joo-Youn Cho Kwang-Hee Shin, In-Jin Jang, Moo-Yong Rhee

Drug Des Devel Ther 2016,Apr;10:1525-31. doi: 10.2147/DDDT.S94694. eCollection 2016.
394

Pharmacokinetics of the evogliptin/metformin extended-release (5/1,000 mg) fixed-dose combination formulation compared to the corresponding loose combination, and food effect in healthy subjects

Su-jin Rhee, SeungHwan Lee, Seo Hyun Yoon, Joo-Youn Cho, In-Jin Jang Kyung-Sang Yu

Drug Des Devel Ther 2016,Apr;10:1411-8. doi: 10.2147/DDDT.S102459. eCollection 2016.
395

Validation of the Korean coefficient for the modification of diet in renal disease study equation.

Oh YJ, Cha RH, Lee SH, Yu KS, Kim SE, Kim H, Kim YS.

Korean J Intern Med 2016,Mar;31(2):344-56. doi: 10.3904/kjim.2015.227. Epub 2016 Jan 13.
396

Phase I Study of CKD-516, a Novel Vascular Disrupting Agent, in Patients with Advanced Solid Tumors.

Oh DY, Kim TM, Han SW, Shin DY, Lee YG, Lee KW, Kim JH, Kim TY, Jang IJ, Lee JS, Bang YJ

Cancer Res Treat. 2016,Jan;48(1):28-36. doi: 10.4143/crt.2014.258. Epub 2015 Feb 23.
397

Inhibition of the MATE transporter by pyrimethamine increases the plasma concentration of metformin but does not increase anti-hyperglycaemic activity in humans.

Oh J, Chung H, Park SI, Yi S, Jang K, Kim A, Yoon J, Cho JY, Yoon SH, Jang IJ, Yu KS, Chung JY.

Diabetes Obes Metab 2016,Jan;18(1):104-108 . doi: 10.1111/dom.12577. Epub 2015 Oct 26.
398

Effects of renal impairment on the pharmacokinetics and pharmacodynamics of a novel DPP-IV inhibitor, evogliptin (DA-1229).

Oh J, Kim AH, Lee S, Cho H, Kim YS, Bahng MY, Yoon SH, Cho JY, Jang IJ, Yu KS

Diabetes Obes Metab 2016,Jan;19(2):294-298. doi: 10.1111/dom.12813. Epub 2016 Nov 24.
399

Combined untargeted and targeted metabolomic profiling reveals urinary biomarkers for discriminating obese from normal-weight adolescents.

Cho K, Moon JS, Kang JH, Jang HB, Lee HJ, Park SI, Yu KS, Cho JY.

Pediatr Obes 2016,Jan;12(2):93-101. doi: 10.1111/ijpo.12114. Epub 2016 Feb 22.
400

Reliable prediction of anti-diabetic drug failure using a reject option

Seokho Kang, Sungzoon Cho ,Su-jin Rhee ,Kyung-Sang Yu

Pattern Analysis and Applications 2016,Jan; Volume 20, Issue 3, pp 883–891
401

Impact of area under the concentration-time curve to minimum inhibitory concentration ratio on vancomycin treatment outcomes in methicillin-resistant Staphylococcus aureus bacteraemia

Song KH, Kim HB, Kim HS, Lee MJ, Jung Y, Kim G, Hwang JH, Kim NH, Kim M, Kim CJ, Choe PG, Chung JY, Park WB, Kim ES, Park KU, Kim NJ, Kim EC, Oh MD.

Int J Antimicrob Agents. 2015,Dec;46(6):689-95. doi: 10.1016/j.ijantimicag.2015.09.010. Epub 2015 Oct 17.
402

Discovery of URAT1 SNPs and association between serum uric acid levels and URAT1

Cho SK, Kim S, Chung JY, Jee SH.

BMJ Open. 2015,Nov;5(11):e009360. doi: 10.1136/bmjopen-2015-009360.
403

The Clinical Significance of Voriconazole Therapeutic Drug Monitoring in Children With Invasive Fungal Infections

Kang HM, Lee HJ, Cho EY, Yu KS, Lee H, Lee JW, Kang HJ, Park KD, Shin HY, Choi EH.

Pediatr Hematol Oncol. 2015,Nov;32(8):557-67. doi: 10.3109/08880018.2015.1088905. Epub 2015 Nov 11.
404

Erratum to: Is Extrapolation of the Safety and Efficacy Data in One Indication to Another Appropriate for Biosimilars?

Lee H.

AAPS J. 2015,Nov;17(6):1520-1. doi: 10.1208/s12248-015-9813-x.
405

Erratum to: Is Extrapolation of the Safety and Efficacy Data in One Indication to Another Appropriate for Biosimilars?

Howard Lee

AAPS J . 2015,Nov;2015 Nov;17(6):1520-1. doi: 10.1208/s12248-015-9813-x.
406

Rapid Hepatobiliary Excretion of Micelle-Encapsulated/Radiolabeled Upconverting Nanoparticles as an Integrated Form

Seo HJ, Nam SH, Im HJ, Park JY, Lee JY, Yoo B, Lee YS, Jeong JM, Hyeon T, Kim JW,Lee JS, Jang IJ, Cho JY, Hwang do W, Suh YD, Lee DS.

Sci Rep. 2015,Oct;5:15685. doi: 10.1038/srep15685.
407

The HLA-A*2402/Cw*0102 haplotype is associated with lamotrigine-induced maculopapular eruption in the Korean population

Moon J, Park HK, Chu K, Sunwoo JS, Byun JI, Lim JA, Kim TJ, Shin JW, Lee ST, Jung KH, Jung KY, Jeon D, Kim DW, Yu KS, Jang IJ, Kang HR, Park HW, Lee SK.

Epilepsia. 2015,Oct;56(10):e161-7. doi: 10.1111/epi.13087. Epub 2015 Aug 17.
408

GWAS identifies two susceptibility loci for lamotrigine-induced skin rash in patients with epilepsy

Jang HW, Kim SW, Cho YJ, Heo K, Lee BI, Lee SK, Jang IJ, Lee MG, Kim WJ, Lee JH.

Epilepsy Res. 2015,Sep;115:88-94. doi: 10.1016/j.eplepsyres.2015.05.014. Epub 2015 Jun 2.
409

Validated LC-MS/MS Assay for the Quantitative Determination of Fimasartan in Human Plasma: Application to Pharmacokinetic Studies

Yoon SH, Oh S, Kim HS, Yi S, Yu KS, Jang IJ, Cho JY.

J Chromatogr Sci. 2015,Sep;53(8):1250-6. doi: 10.1093/chromsci/bmu219. Epub 2015 Jan 22.
410

Pharmacokinetics, pharmacodynamics, and tolerability of LC350189, a novel xanthine oxidase inhibitor, in healthy subjects

Yoon S, Shin D, Lee H, Jang IJ, Yu KS.

Drug Des Devel Ther. 2015,Aug;9:5033-49. doi: 10.2147/DDDT.S86884. eCollection 2015.
411

Pharmacokinetics of Second-Line Antituberculosis Drugs after Multiple Administrations in Healthy Volunteers

Park SI, Oh J, Jang K, Yoon J, Moon SJ, Park JS, Lee JH, Song J, Jang IJ, Yu KS, Chung JY.

Antimicrob Agents Chemother. 2015,Aug;59(8):4429-35. doi: 10.1128/AAC.00354-15. Epub 2015 May 18.
412

Phase I/II Study of Weekly Oraxol for the Second-Line Treatment of Patients With Metastatic or Recurrent Gastric Cancer

Lee KW, Lee KH, Zang DY, Park YI, Shin DB, Kim JW, Im SA, Koh SA, Yu KS, Cho JY, Jung JA,Bang YJ.

Oncologist. 2015,Aug;20(8):896-7. doi: 10.1634/theoncologist.2015-0202. Epub 2015 Jun 25.
413

Comparison of the pharmacokinetics and tolerability of HCP1004 (a fixed-dose combination of naproxen and esomeprazole strontium) and VIMOVO? (a marketed fixed-dose combination of naproxen and esomeprazole magnesium) in healthy volunteers

Choi Y, Han H, Shin D, Lim KS, Yu KS.

Drug Des Devel Ther. 2015,Jul;9:4127-35. doi: 10.2147/DDDT.S86725. eCollection 2015.
414

그래프 모델과 중심성 분석을 이용한 당뇨환자의 처방 및 검사결과의 상관관계 분석

유강민, 박성찬, 이수진, 유경상, 이상구.

정보과학회 컴퓨팅의 실제 논문지 제21권 제7호 2015,Jul;482-487 영문 : Analysis on Correlation between Prescriptions and Test Results of Diabetes Patients using Graph Models and Node Centrality.
415

Efficacy, Safety, and Pharmacokinetics of Beroctocog Alfa in Patients Previously Treated for Hemophilia A

Hyun SY, Park SY, Lee SY, Kook H, Paik SH, Jang IJ, Lee KS.

Yonsei Med J. 2015,Jul;56(4):935-43. doi: 10.3349/ymj.2015.56.4.935.
416

Successful empirical antifungal therapy of intravenous itraconazole with pharmacokinetic evidence in pediatric cancer patients undergoing hematopoietic stem cell transplantation

Kim H, Shin D, Kang HJ, Yu KS, Lee JW, Kim SJ, Kim MS, Song ES, Jang MK, Park JD, Jang IJ, Park KD,Shin HY, Ahn HS.

Clin Drug Investig. 2015,Jul;35(7):437-46. doi: 10.1007/s40261-015-0297-3.
417

Pharmacokinetics and bioequivalence of two different 20 mg olmesartan tablets: A randomized, single-dose, two-period crossover study in healthy Korean male volunteers

Lee JE, Kim AH, Yu KS, Chung JY, Yim SV, Kim BH

TCP. 2015,Jun;23(2):49-53.
418

Bioequivalence study of Donepezil hydrochloride in healthy Korean volunteers

Choi YW, Rhee SJ, Jang IJ, Yu KS, Yim SV, Kim BH.

TCP. 2015,Jun;23(1):26-30.
419

Bioequivalence of the pharmacokinetics between two formulations of 0.2 mg tamsulosin hydrochloride in healthy subjects

Park SI, Rhee SJ, Jang IJ, Yu KS, Yim SV, Kim BH.

TCP. 2015,Jun;23(1):21-25.
420

A pharmacokinetic comparison of two voriconazole formulations and the effect of CYP2C19 polymorphism on their pharmacokinetic profiles

Chung H, Lee H, Han HK, An H, Lim KS, Lee YJ, Cho JY, Yoon SH, Jang IJ, Yu KS.

Drug Des Devel Ther. 2015,May;9:2609-16. doi: 10.2147/DDDT.S80066. eCollection 2015.
421

Intraocular pharmacokinetics of intravitreal vascular endothelial growth factor-Trap in a rabbit model

Park SJ, Oh J, Kim YK, Park JH, Park JY, Hong HK, Park KH, Lee JE, Kim HM, Chung JY, Woo SJ.

Eye (Lond). 2015,Apr;29(4):561-8. doi: 10.1038/eye.2014.329. Epub 2015 Jan 16.
422

Response to "Induction of BOTH P-glycoprotein AND SPECIFIC cytochrome P450 BY aspirin eventually does NOT ALTER the antithrombotic effect of clopidogrel"

Oh J, Ji SC, Lee H, Yu KS, Jang IJ.

Clin Pharmacol Ther. 2015,Apr;97(4):325. doi: 10.1002/cpt.74. Epub 2015 Feb 11.
423

Pharmacokinetic properties and tolerability of rotigotine transdermal patch after repeated-dose application in healthy korean volunteers

Kim BH, Yu KS, Jang IJ, Soo Lim K, Kim JR, Elshoff JP, Andreas JO, Braun M, Cawello W.

Clin Ther. 2015,Apr;37(4):902-12. doi: 10.1016/j.clinthera.2015.01.013. Epub 2015 Mar 16.
424

A fixed-dose combination tablet of gemigliptin and metformin sustained release has comparable pharmacodynamic, pharmacokinetic, and tolerability profiles to separate tablets in healthy subjects

Park SI, Lee H, Oh J, Lim KS, Jang IJ, Kim JA, Jung JH, Yu KS.

Drug Des Devel Ther. 2015,Feb;9:729-36. doi: 10.2147/DDDT.S75980. eCollection 2015.
425

Limited sampling strategy of partial area under the concentration-time curves to estimate midazolam systemic clearance for cytochrome P450 3A phenotyping

Masters JC, Harano DM, Greenberg HE, Tsunoda SM, Jang IJ, Ma JD.

Ther Drug Monit. 2015,Feb;37(1):84-9. doi: 10.1097/FTD.0000000000000116.
426

Pharmacokinetic-pharmacodynamic analysis to evaluate the effect of moxifloxacin on QT interval prolongation in healthy Korean male subjects

Hong T, Han S, Lee J, Jeon S, Park GJ, Park WS, Lim KS, Chung JY, Yu KS, Yim DS.

Drug Des Devel Ther. 2015,Feb;9:1233-45. doi: 10.2147/DDDT.S79772. eCollection 2015.
427

ABCB1 polymorphism as prognostic factor in breast cancer patients treated with docetaxel and doxorubicin neoadjuvant chemotherapy

Kim HJ, Im SA, Keam B, Ham HS, Lee KH, Kim TY, Kim YJ, Oh DY, Kim JH, Han W, Jang IJ, Kim TY, Park IA, Noh DY.

Cancer Sci. 2015,Jan;106(1):86-93. doi: 10.1111/cas.12560. Epub 2014 Dec 8.
428

Favorable outcome of hematopoietic stem cell transplantation using a targeted once-daily intravenous busulfan-fludarabine-etoposide regimen in pediatric and infant acute lymphoblastic leukemia patients

Lee JW, Kang HJ, Kim S, Lee SH, Yu KS, Kim NH, Jang MK, Kim H, Song SH, Park JD, Park KD, Shin HY, Jang IJ, Ahn HS.

Biol Blood Marrow Transplant. 2015,Jan;21(1):190-5. doi: 10.1016/j.bbmt.2014.09.013. Epub 2014 Sep 22.
429

Antihyperglycemic mechanism of metformin occurs via the AMPK/LXRα/POMC pathway

Cho K, Chung JY, Cho SK, Shin HW, Jang IJ, Park JW, Yu KS, Cho JY

Sci Rep. 2015,Jan;5:8145. doi: 10.1038/srep08145.
430

An efficient and effective ensemble of support vector machines for anti-diabetic drug failure prediction.

Kang, S. , Kang, P. , Ko, T. , Cho, S. , Rhee, S.j. , Yu, K.S.

Expert Systems with Applications 2015,Jan;4265-4273
431

A bioequivalence study of two levofloxacin tablets in healthy male subjects

Chung I, Yoon S, Yi S, Kim BH, Yim SV, Jang IJ, Lee H.

Transl Clin Pharmacol 2014,Dec;22(2):102-105.
432

Verapamil decreases the glucose-lowering effect of metformin in healthy volunteers.

Cho SK, Kim CO, Park ES, Chung JY.

Br J Clin Pharmacol 2014,Dec;78(6):1426-32. doi: 10.1111/bcp.12476.
433

Evaluation of the pharmacokinetic and pharmacodynamic drug interactions between cilnidipine and valsartan, in healthy volunteers.

Lee J, Lee H, Jang K, Lim KS, Shin D, Yu KS.

Drug Des Devel Ther 2014,Oct;8:1781-8. doi: 10.2147/DDDT.S68574. eCollection 2014.
434

Multiple-dose pharmacokinetics and pharmacodynamics of evogliptin (DA-1229), a novel dipeptidyl peptidase IV inhibitor, in healthy volunteers.

Gu N, Park MK, Kim TE, Bahng MY, Lim KS, Cho SH, Yoon SH, Cho JY, Jang IJ, Yu KS.

Drug Des Devel Ther 2014,Oct;8:1709-21. doi: 10.2147/DDDT.S65678. eCollection 2014.
435

Effect of renal function on the pharmacokinetics of fimasartan: a single-dose, open-label, Phase I study.

Seokuee Kim, Jongtae Lee, Donghoon Shin, Kyoung Soo Lim, Yon Su Kim, In-Jin Jang

Drug Des Devel Ther 2014,Oct;8:1723-31. doi: 10.2147/DDDT.S68784. eCollection 2014.
436

Korean, Japanese, and Chinese populations featured similar genes encoding drug-metabolizing enzymes and transporters: a DMET Plus microarray assessment.

Yi S, An H, Lee H, Lee S, Ieiri I, Lee Y, Cho JY, Hirota T, Fukae M, Yoshida K, Nagatsuka S, Kimura M, Irie S, Sugiyama Y, Shin DW, Lim KS, Chung JY, Yu KS, Jang IJ.

Pharmacogenet Genomics 2014,Oct;24(10):477-85. doi: 10.1097/FPC.0000000000000075.
437

Trough concentration over 12.1 mg/L is a major risk factor of vancomycin-related nephrotoxicity in patients with therapeutic drug monitoring.

Han H, An H, Shin KH, Shin D, Lee S, Kim JH, Cho SH, Kang HR, Jang IJ, Yu KS, Lim KS.

Ther Drug Monit 2014,Oct;36(5):606-11. doi: 10.1097/FTD.0000000000000061.
438

Pharmacokinetic-Pharmacodynamic Relationships of Macitentan, a New Endothelin Receptor Antagonist, After Multiple Dosing in Healthy Korean Subjects.

Ahn LY, Kim SE, Yi S, Dingemanse J, Lim KS, Jang IJ, Yu KS.

Am J Cardiovasc Drugs 2014,Oct;14(5):377-85. doi: 10.1007/s40256-014-0081-4.
439

Pharmacokinetics and tolerability of the new second-generation nonnucleoside reverse- transcriptase inhibitor KM-023 in healthy subjects.

Cha YJ, Lim KS, Park MK, Schneider S, Bray B, Kang MC, Chung JY, Yoon SH, Cho JY, Yu KS.

Drug Des Devel Ther 2014,Sep;8:1613-9. doi: 10.2147/DDDT.S65596. eCollection 2014.
440

노인의 임상시험 참여에 대한 현황과 향후 발전 방향 : 임상시험 전문가를 대상으로 한 설문조사 분석

김선욱, 정희원, 박미란, 정재용, 이근욱, 김지현, 이종석, 김광일, 김철호.

J Korean Geriatr Soc 2014,Sep;18(3):122-135.
441

Effects of HM30181, a P-glycoprotein inhibitor, on the pharmacokinetics and pharmacodynamics of loperamide in healthy volunteers.

Kim TE, Lee H, Lim KS, Lee S, Yoon SH, Park KM, Han H, Shin SG, Jang IJ, Yu KS, Cho JY.

Br J Clin Pharmacol 2014,Sep;78(3):556-64. doi: 10.1111/bcp.12368.
442

Predictive performance of gentamicin dosing nomograms.

Lee J, Yoon S, Shin D, Han H, An H, Lee J, Lim KS, Yu KS, Lee H.

Drug Des Devel Ther 2014,Aug;8:1097-106. doi: 10.2147/DDDT.S66981. eCollection 2014.
443

Investigation of bioequivalence of a new fixed-dose combination of acarbose and metformin with the corresponding loose combination as well as the drug-drug interaction potential between both drugs in healthy adult male subjects.

Kim S, Jang IJ, Shin D, Shin DS, Yoon S, Lim KS, Yu KS, Li J, Zhang H, Liu Y, Brendel E, Blode H, Wang Y.

J Clin Pharm Ther 2014,Aug;39(4):424-31. doi: 10.1111/jcpt.12166. Epub 2014 May 8.
444

An assessment of the pharmacokinetics, pharmacodynamics, and tolerability of GCPGC, a novel pegylated granulocyte colony-stimulating factor (G-CSF), in healthy subjects.

Shin KH, Lim KS, Lee H, Jang IJ, Yu KS.

Invest New Drugs 2014,Aug;32(4):636-43. doi: 10.1007/s10637-014-0068-7. Epub 2014 Jan 28.
445

A Phase I Study of Oral Paclitaxel with a Novel P-Glycoprotein Inhibitor, HM30181A, in Patients with Advanced Solid Cancer.

Lee HJ, Heo DS, Cho JY, Han SW, Chang HJ, Yi HG, Kim TE, Lee SH, Oh DY, Im SA, Jang IJ, Bang YJ.

Cancer Res Treat 2014,Jul;46(3):234-42. doi: 10.4143/crt.2014.46.3.234. Epub 2014 Jul 15.
446

Tolerability and Pharmacokinetics of Lobeglitazone, a Novel Peroxisome Proliferator-Activated Receptor-γ Agonist, After a Single Oral Administration in Healthy Female Subjects.

Park MK, Kim TE, Kim J, Kim C, Yoon SH, Cho JY, Jang IJ, Yu KS, Lim KS.

Clin Drug Investig 2014,Jul;34(7):467-74. doi: 10.1007/s40261-014-0197-y.
447

Effects of proton pump inhibitors on metformin pharmacokinetics and pharmacodynamics.

Kim A, Chung I, Yoon SH, Yu KS, Lim KS, Cho JY, Lee H, Jang IJ, Chung JY.

Drug Metab Dispos 2014,Jul;42(7):1174-9. doi: 10.1124/dmd.113.055616. Epub 2014 Apr 24.
448

A rapid, simple and reliable HPLC-triple quadrupole tandem mass spectrometer method for a simultaneous quantification of irinotecan and its active metabolite 7-ethyl-10-hydroxycamptothecin (SN38) in mouse plasma.

Ahn G, Park DM, Park JW, Kim HY, Cho JY, Rhee SJ, Jang IJ, Kim HK.

Biomed Chromatogr 2014,Jul;28(7):919-22. doi: 10.1002/bmc.3134. Epub 2014 Jan 23.
449

Novel nanocrystal formulation of megestrol acetate has improved bioavailability compared with the conventional micronized formulation in the fasting state.

Jang K, Yoon S, Kim SE, Cho JY, Yoon SH, Lim KS, Yu KS, Jang IJ, Lee H.

Drug Des Devel Ther 2014,Jun;8:851-8. doi: 10.2147/DDDT.S62176. eCollection 2014.
450

Genetic Polymorphisms of the Carboxylesterase 1 (CES1)Gene in a Korean Population.

Cha YJ, Jeong HE, Shin JG, Kim EY, Yu KS, Cho JY, Yoon SH, Lim KS.

Transl Clin Pharmacol 2014,Jun;22(1):30-34.
451

Pregnane X Receptor agonist Increases the __EXPRESSION__ Levels of the Plasma Membrane Monoamine Transporter.

Cho SK, Oh H, Hong SH, Park MS, Chung JY.

Transl Clin Pharmacol 2014,Jun;22(1):19-21.
452

The Effects of Moxifloxacin on QTc Interval in Healthy Korean Male Subjects.

Moon SJ, Lee J, An H, Yim DS, Chung JY, Yu KS, Cho JY, Lim KS.

Drugs R D 2014,Jun;14(2):63-71. doi: 10.1007/s40268-014-0040-1.
453

Aspirin decreases systemic exposure to clopidogrel through modulation of p-glycoprotein but does not alter its antithrombotic activity.

Oh J, Shin D, Lim KS, Lee S, Jung KH, Chu K, Hong KS, Shin KH, Cho JY, Yoon SH, Ji SC, Yu KS, Lee H, Jang IJ.

Clin Pharmacol Ther 2014,Jun;95(6):608-16. doi: 10.1038/clpt.2014.49. Epub 2014 Feb 24.
454

Pharmacokinetic and pharmacodynamic interaction between gemigliptin and metformin in healthy subjects.

Shin D, Cho YM, Lee S, Lim KS, Kim JA, Ahn JY, Cho JY, Lee H, Jang IJ, Yu KS.

Clin Drug Investig 2014,Jun;34(6):383-93. doi: 10.1007/s40261-014-0184-3.
455

Pharmacodynamics, Pharmacokinetics, and Tolerability of Intravenous or Subcutaneous GC1113, a Novel Erythropoiesis-Stimulating Agent.

Han H, Lee J, Shin D, Shin KH, Jeon H, Lim KS, Yoon SH, Shin SG, Jang IJ, Cho JY, Yu KS.

Clin Drug Investig 2014,Jun;34(6):373-82. doi: 10.1007/s40261-014-0183-4.
456

Effect of preservation conditions on cartilage tissue for cell transplantation.

Kim BY, Nam BM, Lee KM, Jo YH, Nemeno JG, Yang W, Lee S, Kim H, Jang IJ, Takebe T, Lee JI.

Transplant Proc 2014,May;46(4):1139-44. doi: 10.1016/j.transproceed.2013.11.125.
457

Voriconazole Therapeutic Drug Monitoring is Necessary for Children with Invasive Fungal Infection.

Kang HM, Kang SY, Cho EY, Yu KS, Lee JW, Kang HJ, Park KD, Shin HY, Ahn HS, Lee H, Choi EH, Lee HJ.

Korean J Pediatr Infect Dis 2014,Apr;21(1):9-21.
458

Seasonal variation in hemoglobin a1c in korean patients with type 2 diabetes mellitus.

Kim YJ, Park S, Yi W, Yu KS, Kim TH, Oh TJ, Choi J, Cho YM.

J Korean Med Sci 2014,Apr;29(4):550-5. doi: 10.3346/jkms.2014.29.4.550. Epub 2014 Apr 1.
459

Dose selection method for pharmacokinetic study in hemodialysis patients using a subpharmacological dose: oseltamivir as a model drug.

Kim DK, Lee JW, Shin KH, Kim S, Oh KH, Kim M, Yu KS, Lee JP, Lim CS, Kim YS, Joo KW.

BMC Nephrol 2014,Mar;15:46. doi: 10.1186/1471-2369-15-46.
460

Area under the concentration-time curve to minimum inhibitory concentration ratio as a predictor of vancomycin treatment outcome in methicillin-resistant Staphylococcus aureus bacteraemia

Jung Y, Song KH, Cho JE, Kim HS, Kim NH, Kim TS, Choe PG, Chung JY, Park WB, Bang JH, Kim ES, Park KU, Park SW, Kim HB, Kim NJ, Oh MD.

Int J Antimicrob Agents 2014,Feb;43(2):179-83. doi: 10.1016/j.ijantimicag.2013.10.017. Epub 2013 Nov 18.
461

Area under the concentration-time curve to minimum inhibitory concentration ratio as a predictor of vancomycin treatment outcome in methicillin-resistant Staphylococcus aureus bacteraemia.

Jung Y, Song KH, Cho Je, Kim HS, Kim NH, Kim TS, Choe PG, Chung JY, Park WB, Bang JH, Kim ES, Park KU, Park SW, Kim HB, Kim NJ, Oh MD.

Int J Antimicrob Agents 2014,Feb;43(2):179-83. doi: 10.1016/j.ijantimicag.2013.10.017. Epub 2013 Nov 18.
462

Investigating the different mechanisms of genotoxic and non-genotoxic carcinogens by a gene set analysis.

Lee WJ, Kim SC, Lee SJ, Lee J, Park JH, Yu KS, Lim J, Kwon SW.

PLoS One 2014,Jan;9(1):e86700. doi: 10.1371/journal.pone.0086700. eCollection 2014.
463

Intraocular pharmacokinetics of ranibizumab in vitrectomized versus nonvitrectomized eyes.

Ahn SJ, Ahn J, Park S, Kim H, Hwang DJ, Park JH, Park JY, Chung JY, Park KH, Woo SJ.

Invest Ophthalmol Vis Sci 2014,Jan;55(1):567-73. doi: 10.1167/iovs.13-13054.
464

Comparative steady-state pharmacokinetic study of an extended-release formulation of itopride and its immediate-release reference formulation in healthy volunteers.

Yoon S, Lee H, Kim TE, Lee S, Chee DH, Cho JY, Yu KS, Jang IJ.

Drug Des Devel Ther 2014,Jan;8:123-8. doi: 10.2147/DDDT.S53027. eCollection 2014.
465

Development of lipidomic platform and phosphatidylcholine retention time index for lipid profiling of rosuvastatin treated human plasma

Choi JM, Kim TE, Cho JY, Lee HJ, Jung BH.

J Chromatogr B Analyt Technol Biomed Life Sci 2014,Jan;944:157-65. doi: 10.1016/j.jchromb.2013.10.029. Epub 2013 Oct 26.
466

Modified titanium implant as a gateway to the human body: the implant mediated drug delivery system.

Park YS, Cho JY, Lee SJ, Hwang CI.

Biomed Res Int 2014,Jan;801358. doi: 10.1155/2014/801358. Epub 2014 Jul 22.
467

Development of lipidomic platform and phosphatidylcholine retention time index for lipid profiling of rosuvastatin treated human plasma.

Choi JM, Kim TE, Cho JY, Lee HJ, Jung BH.

J Chromatogr B Analyt Technol Biomed Life Sci 2014,Jan;944:157-65. doi: 10.1016/j.jchromb.2013.10.029. Epub 2013 Oct 26.
468

Pharmacokinetics, Safety and Tolerability of DA-6034, an Anti-Inflammatory Agent, After Single and Multiple Oral Administrations in Healthy Volunteers.

Lee J, Shin KH, Kim JR, Lim KS, Jang IJ, Chung JY.

Clin Drug Investig 2014,Jan;34(1):37-42. doi: 10.1007/s40261-013-0147-0.
469

Quantification of human plasma-busulfan concentration by liquid chromatography-tandem mass spectrometry.

Moon SY, Lim MK, Hong S, Jeon Y, Han M, Song SH, Lim KS, Yu KS, Jang IJ, Lee JW, Kang HJ, Song J.

Ann Lab Med 2014,Jan;34(1):7-14. doi: 10.3343/alm.2014.34.1.7. Epub 2013 Dec 6.
470

Is extrapolation of the safety and efficacy data in one indication to another appropriate for biosimilars?

Lee H.

AAPS J 2014,Jan;16(1):22-6. doi: 10.1208/s12248-013-9534-y. Epub 2013 Oct 11.
471

Pharmacokinetic Properties and Effects of PT302 After Repeated Oral Glucose Loading Tests in a Dose-Escalating Study.

Gu N, Cho SH, Kim J, Shin D, Seol E, Lee H, Lim KS, Shin SG, Jang IJ, Yu KS.

Clin Ther 2014,Jan;36(1):101-14. doi: 10.1016/j.clinthera.2013.12.002. Epub 2013 Dec 27.
472

건강한 한국인 자원자에서 T-614의 단회 경구 투여 후 약동학적 특성에 대한 연구

신동성, 김보형, 김정렬, 임경수, 장인진, 신상구, 유경상.

대한임상약리학회지 2013,Dec;21(2):150-158
473

건강한 자원자에서 JES9501 단회 및 반복 경구투여 후 안전성 및 약동

김언혜, 김보형, 신동성, 조주연, 유경상, 장인진, 정재용.

대한임상약리학회지 2013,Dec;21(2):141-149
474

건강한 한국인 피험자에서 염산세프카펜 피복실 단회 경구투여 시 약동학적 특성에 관한 연구

이수진, 신광희, 차유정, 김정렬, 오달석, 조주연, 유경상, 장인진, 정재용, 임경수.

대한임상약리학회지 2013,Dec;21(2):104-112
475

Development and validation of a microfluidic chip-based nano-liquid chromatography-triple quadrupole tandem mass spectrometry method for a sensitive and reliable quantification of 7-ethyl-10-hydroxycamptothecin (SN38) in mouse plasma

Ahn G, Park DM, Park JW, Cho JY, Rhee SJ, Kim HY, Lee DS, Jang IJ, Kim HK.

Anal Bioanal Chem 2013,Dec;405(30):9817-24. doi: 10.1007/s00216-013-7411-2. Epub 2013 Oct 15.
476

Relationship between absolute neutrophil count profiles and pharmacokinetics of DA-3031, a pegylated granulocyte colony-stimulating factor (pegylated-G-CSF): a dose block-randomized, double-blind, dose-escalation study in healthy subjects

Ahn LY, Shin KH, Lim KS, Kim TE, Jeon H, Yoon SH, Cho JY, Shin SG, Jang IJ, Yu KS.

Clin Drug Investig 2013,Nov;33(11):817-24.
477

Evaluation of endogenous metabolic markers of hepatic CYP3A activity using metabolic profiling and midazolam clearance

Shin KH, Choi MH, Lim KS, Yu KS, Jang IJ, Cho JY.

Clin Pharmacol Ther 2013,Nov;94(5):601-9. doi: 10.1038/clpt.2013.128. Epub 2013 Jun 19.
478

Comparison of pharmacokinetics between new quinolone antibiotics: the zabofloxacin hydrochloride capsule and the zabofloxacin aspartate tablet

Han H, Eun Kim S, Shin KH, Lim C, Soo Lim K, Yu KS, Cho JY.

Curr Med Res Opin 2013,Oct;29(10):1349-55. doi: 10.1185/03007995.2013.825591. Epub 2013 Aug 19.
479

Usefulness of oral loading of oxcarbazepine suspension in selected patients with epilepsy

Kim DW, Gu N, Lee H, Jang IJ, Chu K, Yu KS, Cho JY, Yoon SH, Na HJ, Lee SK.

Int J Clin Pharmacol Ther 2013,Oct;51(10):780-6. doi: 10.5414/CP201896.
480

Genetic algorithm guided population pharmacokinetic model development for simvastatin, concurrently or non-concurrently co-administered with amlodipine

Chaturvedula A, Sale ME, Lee H.

J Clin Pharmacol 2013,Sep;doi: 10.1002/jcph.176. [Epub ahead of print]
481

Ambulatory Blood Pressure Response to Once-Daily Fimasartan: An 8-Week, Multicenter, Randomized, Double-Blind, Active-Comparator, Parallel-Group Study in Korean Patients With Mild To Moderate Essential Hypertension

Lee H, Kim KS, Chae SC, Jeong MH, Kim DS, Oh BH

Clin Ther 2013,Sep;35(9):1337-49. doi: 10.1016/j.clinthera.2013.06.021. Epub 2013 Aug 7.
482

GC-MS-Based Quantitative Signatures of Cytochrome P450-Mediated Steroid Oxidation Induced by Rifampicin

Moon JY, Kang SM, Lee J, Cho JY, Moon MH, Jang IJ, Chung BC, Choi MH.

Ther Drug Monit 2013,Aug;35(4):473-84. doi: 10.1097/FTD.0b013e318286ee02.
483

Pharmacokinetic-pharmacodynamic modelling of biomarker response to sitagliptin in healthy volunteers

Kim BH, Kim SE, Kang D, Lim KS, Kim JR, Jang IJ, Shin SG, Yoon SH, Cho JY, Yu KS.

Basic Clin Pharmacol Toxicol 2013,Aug;113(2):113-25. doi: 10.1111/bcpt.12068. Epub 2013 May 20.
484

Sustained Increase in the Oral Bioavailability of Loperamide after a Single Oral Dose of HM30181, a P-glycoprotein Inhibitor, in Healthy Male Subjects

Cha YJ, Lee H, Gu N, Kim TE, Lim KS, Yoon SH, Chung JY, Jang IJ, Shin SG, Yu KS, Cho JY.

Basic Clin Pharmacol Toxicol 2013,Jul;doi: 10.1111/bcpt.12108. [Epub ahead of print]
485

건강한 한국인 자원자에서 보글리보스 제제의 약효 동등성 평가 항목 선정을 위한 위약 대조, 단회 및 반복 투여 후 약력학 특성 비교 임상시험

장경호, 조상헌, 김정렬, 정재용, 임경수, 장인진, 유경상.

대한임상약리학회지 2013,Jun; 21(1):63-70
486

건강한 한국인에서 Zofenopril의 약동/약력학적 특성 및 내약성에 관한 무작위, 위약대조, 이중맹검, 평행군, 반복투여, 단계적 증량 임상연구

오재성, 이승환, 임경수, 정재용, 신상구, 장인진, 유경상.

대한임상약리학회지 2013,Jun; 21(1):52-62
487

건강한 자원자에서 무르페ⓡ 패치와 트라스트ⓡ 패치 투여 시 약동학적 특성 및 피부자극성을 비교 평가하기 위한 무작위배정, 공개, 2-Way 교차 임상 연구

최윤정, 김영미, 정재용, 조주연, 유경상, 장인진, 임경수.

대한임상약리학회지 2013,Jun; 21(1):41-51
488

Pharmacokinetic and Pharmacodynamic Effects of Prasugrel in Healthy Korean Males

Yu KS, Park KW, Kelly RP, Gu N, Payne C, Small DS, Choi HC, Kawakatsu E, Pinton P.

J Cardiovasc Pharmacol 2013,Jun;62(1):72-77.
489

Functional characterization of MATE2-K genetic variants and their effects on metformin pharmacokinetics

Chung JY, Cho SK, Kim TH, Kim KH, Jang GH, Kim CO, Park EM, Cho JY, Jang IJ, Choi JH.

Pharmacogenet Genomics 2013,Jun;23(7):365-73. doi: 10.1097/FPC.0b013e3283622037.
490

Pharmacokinetic study of single and multiple oral administrations of 2 mg dienogest in healthy Korean women

Shin D, Lee S, Lim KS, Park JS, Shin SG, Jang IJ, Yu KS.

Contraception 2013,Jun;87(6):750-5. doi: 10.1016/j.contraception.2012.10.033. Epub 2012 Dec 4.
491

The effect of udenafil on the hemodynamics of healthy male volunteers administered tamsulosin

Kim MG, Kim JR, Kim BH, Lim KS, Shin SG, Jang IJ, Yu KS, Cho JY.

Curr Med Res Opin 2013,Jun;29(6):685-93. doi: 10.1185/03007995.2013.792792. Epub 2013 Apr 17.
492

Population pharmacokinetics of theophylline in premature Korean infants

Kim SE, Kim BH, Lee S, Sohn JA, Kim HS, Cho JY, Yoon SH, Jang IJ, Yu KS, Lim KS.

Ther Drug Monit 2013,Jun;35(3):338-44. doi: 10.1097/FTD.0b013e3182866695.
493

The relationship between antipsychotic D2 occupancy and change in frontal metabolism and working memory : A dual [(11)C]raclopride and [(18)F]FDG imaging study with aripiprazole

Kim E, Howes OD, Turkheimer FE, Kim BH, Jeong JM, Kim JW, Lee JS, Jang IJ, Shin SG, Kapur S, Kwon JS.

Psychopharmacology (Berl) 2013,May;227(2):221-9. doi: 10.1007/s00213-012-2953-0. Epub 2012 Dec 28.
494

Pharmacokinetic and pharmacodynamic properties of a new long-acting granulocyte colony-stimulating factor (HM10460A) in healthy volunteers

Shin KH, Kim TE, Lim KS, Yoon SH, Cho JY, Kim SE, Park KM, Shin SG, Jang IJ, Yu KS.

BioDrugs 2013,Apr;27(2):149-58. doi: 10.1007/s40259-013-0010-0.
495

Exploration of optimal dosing regimens of haloperidol, a D2 Antagonist, via modeling and simulation analysis in a D2 receptor occupancy study

Lim HS, Kim SJ, Noh YH, Lee BC, Jin SJ, Park HS, Kim S, Jang IJ, Kim SE.

Pharm Res 2013,Mar;30(3):683-93. doi: 10.1007/s11095-012-0906-2. Epub 2012 Nov 10.
496

Global metabolomics and targeted steroid profiling reveal that rifampin, a strong human PXR activator, alters endogenous urinary steroid markers

Kim B, Moon JY, Choi MH, Yang HH, Lee S, Lim KS, Yoon SH, Yu KS, Jang IJ, Cho JY.

J Proteome Res 2013,Mar;12(3):1359-68. doi: 10.1021/pr301021p. Epub 2013 Jan 28.
497

Effect of dissolved oxygen in alcoholic beverages and drinking water on alcohol elimination in humans.

Rhee SJ, Chae JW, Song BJ, Lee ES, Kwon KI.

Alcohol 2013,Feb;47(1):27-30.
498

Impact of ABCC2, ABCG2 and SLCO1B1 Polymorphisms on the Pharmacokinetics of Pitavastatin in Humans

Oh ES, Kim CO, Cho SK, Park MS, Chung JY.

Drug Metab Pharmacokinet 2013,Jan;28(3):196-202. Epub 2012 Sep 25.
499

Serum cystatin C is a major predictor of vancomycin clearance in a population pharmacokinetic analysis of patients with normal serum creatinine concentrations

Chung JY, Jin SJ, Yoon JH, Song YG.

J Korean Med Sci 2013,Jan;28(1):48-54. doi: 10.3346/jkms.2013.28.1.48. Epub 2013 Jan 8.
500

Apple juice greatly reduces systemic exposure to atenolol

Jeon H, Jang IJ, Lee S, Ohashi K, Kotegawa T, Ieiri I, Cho JY, Yoon SH, Shin SG, Yu KS, Lim KS.

Br J Clin Pharmacol 2013,Jan;75(1):172-9. doi: 10.1111/j.1365-2125.2012.04324.x.
501

Increased systemic exposure of fimasartan, an angiotensin II receptor antagonist, by ketoconazole and rifampicin

Kim JW, Yi S, Kim TE, Lim KS, Yoon SH, Cho JY, Lee MG, Song IS, Shin SG, Jang IJ, Yu KS.

J Clin Pharmacol 2013,Jan;53(1):75-81. doi: 10.1177/0091270011433328. Epub 2013 Jan 24.
502

Pharmacokinetic Characteristics of Cefcapene Pivoxil Hydrochloride after Single Oral Administration in Healthy Korean Subjects

이수진, 신광희, 차유정, 김정렬, 오달석, 조주연, 유경상, 장인진, 정재용, 임경수

Translational and Clinical Pharmacology 2013,Jan;2013, vol.21, no.2, pp. 104-112 (9 pages) 건강한 한국인 피험자에서 염산세프카펜 피복실 단회 경구투여 시 약동학적 특성에 관한 연구
503

Investigation Study on Gender Difference Based on Korean Data Related to Drug Use

이수진, 이병요, 권광일

한국임상약학회지 2013,Jan;2013, vol.23, no.2, pp. 114-122 (9 pages) 의약품 사용 관련 국내 통계자료에 나타난 성별 차이 조사 연구
504

Pharmacokinetics and pharmacodynamics of intravenous dexmedetomidine in healthy Korean subjects

Lee S, Kim BH, Lim K, Stalker D, Wisemandle W, Shin SG, Jang IJ, Yu KS.

J Clin Pharm Ther 2012,Dec;37(6):698-703
505

Tolerability and Pharmacokinetics Following a Single Dose of Vardenafil in Healthy Korean Volunteers

Seokuee Kim, SeungHwan Lee, Kyoung Soo Lim, Hyeong-Seok Lim, Sang-Goo Shin, In-Jin Jang, and Kyung-Sang Yu

Korean Society for Clinical Pharmacology and Therapeutics 2012,Dec;20(2):125-134. Korean. Published online Dec 31, 2012. https://doi.org/10.12793/jkscpt.2012.20.2.125
506

Pharmacodynamic comparison of two formulations of Acarbose 100-mg tablets

Lee S, Chung JY, Hong KS, Yang SH, Byun SY, Lim HS, Shin SG, Jang IJ, Yu KS.

J Clin Pharm Ther 2012,Oct;37(5):553-7.
507

The effect of therapeutic drug monitoring on safety and efficacy of voriconazole in invasive fungal infections: A randomized controlled trial

Park WB, Kim NH, Kim KH, Lee SH, Nam WS, Yoon SH, Song KH, Choe PG, Kim NJ, Jang IJ, Oh MD, Yu KS.

Clin Infect Dis 2012,Oct; 55(8):1080-7.
508

Multiple-dose pharmacokinetics of fesoterodine sustained-release in healthy Korean volunteers

Shin D, Shin KH, Lee S, Lim KS, Cho JY, Jang IJ, Shin SG, Yu KS.

Int J Clin Pharmacol Ther 2012,Oct;50(10):722-8
509

Assessment of the effect of mirodenafil on the hemodynamics of healthy male korean volunteers administered tamsulosin: a randomized, double-blind, placebo-controlled, 2-period crossover study

NY Gu, JW Kim, KS Lim, KH Shin, TE Kim, BY Lee, SG Shin, IJ Jang, KS Yu.

Clin Ther 2012,Sep;34(9):1929-1939
510

Evaluation of the pharmacokinetics, food effect, pharmacodynamics, and tolerability of DA-1229, a dipeptidyl peptidase IV inhibitor, in healthy volunteers: first-in-human study

TE Kim, KS Lim, MK Park, SH Yoon, JY Cho, SG Shin, IJ Jang, KS Yu.

Clin Ther 2012,Sep;34(9):1986-1998
511

Highly variable pharmacokinetics of once-daily intravenous busulfan when combined with fludarabine in pediatric patients: phase I clinical study for determination of optimal once-daily busulfan dose using pharmacokinetic modeling

Lee JW, Kang HJ, Lee SH, Yu KS, Kim NH, Yuk YJ, Jang MK, Han EJ, Kim H, Song SH, Park KD, Shin HY, Jang IJ, Ahn HS.

Biol Blood Marrow Transplant 2012,Jun;18(6):944-50
512

Assessment of the analgesic effect of remifentanil using three pain models in healthy Korean volunteers: a randomized, controlled study

Kim TE, Kim KP, Shin D, Chung YJ, Price J, Mistry P, Jang IJ, Yu KS.

Basic Clin Pharmacol Toxicol 2012,Jun;110(6):518-23.
513

Assessment of the pharmacokinetics of co-administered metformin and lobeglitazone, a thiazolidinedione antihyperglycemic agent, in healthy subjects

Shin D, Kim TE, Yoon SH, Cho JY, Shin SG, Jang IJ, Yu KS.

Curr Med Res Opin 2012,Jun;28(7):1213-20.
514

The effect of fimasartan, an angiotensin receptor type 1 blocker, on the pharmacokinetics and pharmacodynamics of warfarin in healthy korean male volunteers: a one-sequence, two-period crossover clinical trial

Gu N, Kim BH, Lim KS, Kim SE, Nam WS, Yoon SH, Cho JY, Shin SG, Jang IJ, Yu KS.

Clin Ther 2012,Jun;34(7):1592-600.
515

Apple juice greatly reduces systemic exposure to atenolol

Jeon HW, Jang IJ, Lee S, Ohashi K, Kotegawa T, Ieiri I, Cho JY, Yoon SH, Shin SG, Yu KS, Lim KS.

Br J Clin Pharmacol 2012,May;doi: 10.1111/j.1365-2125.2012.04324.x. [Epub ahead of print]
516

Pharmacokinetic and pharmacodynamic properties of the calcimimetic agent cinacalcet (KRN1493) in healthy male Korean subjects: a randomized, open-label, single ascending-dose, parallel-group study

Lee S, Gu NY, Kim BH, Lim KS, Shin SG, Jang IJ, Yu KS.

Clin Ther 2012,May;34(5):1160-9.
517

Assessment of pharmacokinetic proportionality of levofloxacin and cyclosporine over a 100-fold dose range in healthy human volunteers

Lim MS, Seong SJ, Park J, Seo JJ, Lee J, Yu KS, Lee HW, Yoon YR.

Expert Opin Drug Metab Toxicol 2012,Apr;8(4):399-405.
518

Pharmacokinetics and pharmacodynamics of oral tolvaptan administered in 15- to 60-mg single doses to healthy Korean men

Yi S, Jeon H, Yoon SH, Cho JY, Shin SG, Jang IJ, Yu KS.

J Cardiovasc Pharmacol 2012,Apr;59(4):315-22.
519

Predicting brain occupancy from plasma levels using PET: superiority of combining pharmacokinetics with pharmacodynamics while modeling the relationship

Kim ET, Oliver D Howes, Kim BH, Jeong JM, Lee JS, Jang IJ, Shin SG, FE. Turkheimer, ST Kapur, Kwon JS.

J.Cereb. Blood Flow Metab. 2012,Apr;32(4):759-68
520

A positron emission tomography microdosing study with sertraline in healthy volunteers

Shin KH, Kim KP, Lim KS, Kim JW, Lee YS, Yang BY, Lee JS, Jung JM, Yoon SH, Jang IJ, Yu KS.

Int J Clin Pharmacol Ther 2012,Mar;50(3):224-32.
521

Frequency of CYP2C9 variant alleles, including CYP2C9*13 in a Korean population and effect on glimepiride pharmacokinetics

Lee HW, Lim MS, Lee J, Jegal MY, Kim DW, Lee WK, Jang IJ, Shin JG, Yoon YR.

J Clin Pharm Ther 2012,Feb;37(1):105-11
522

Effect of oseltamivir on bleeding risk associated with warfarin therapy: a retrospective review

Lee SH, Kang HR, Jung JW, Kwon JW, Hong KS, Yu KS, Cho SH.

Clin Drug Investig 2012,Feb;32(2):131-7
523

Tolerability and pharmacokinetics of a new P-glycoprotein inhibitor, HM30181, in healthy Korean male volunteers: single- and multiple-dose randomized, placebo-controlled studies

Kim TE, Gu N, Yoon SH, Cho JY, Park KM, Shin SG, Jang IJ, Yu KS.

Clin Ther 2012,Feb;34(2):482-94
524

Increased systemic exposure of fimasartan, an angiotensin II receptor antagonist, by ketoconazole and rifampicin

Kim JW, Yi S, Kim TE, Lim KS, Yoon SH, Cho JY, Lee MG, Song IS, Shin SG, Jang IJ, Yu KS.

J Clin Pharmacol 2012,Jan;[Epub ahead of print]
525

Pharmacokinetics of a fixed-dose glimepiride/sustained-release metformin combination

Kim KP, Lim KS, Kim BH, Shin HS, Cho JY, Shin SG, Jang IJ, Yu KS.

Int J Clin Pharmacol Ther 2012,Jan;50(2):142-9.
526

Pharmacokinetics of lacosamide in healthy korean male volunteers

Kim SE, Gu NY, Kim BH, Fitchner A, Elshoff JP, Cawello W, Jang IJ, Yu KS.

Pharmacol 2012,Jan;89(3-4):172-8
527

Comparative pharmacokinetics of HD203, a biosimilar of etanercept, with marketed etanercept (Enbrel): a double-blind, single-dose, crossover study in healthy volunteers

Yi S, Kim SE, Park MK, Yoon SH, Cho JY, Lim KS, Shin SG, Jang IJ, Yu KS.

BioDrugs 2012,Jan;26(3):177-84
528

Assessment of the drug-drug interactions between fimasartan and hydrochlorothiazide in healthy volunteer

Jeon HW, Lim KS, Shin KH, Kim JW, Yoon SH, Cho JY, Shin SG, Jang IJ, Yu KS.

J Cardiovasc Pharmacol 2012,Jan;59(1):84-91
529

Voriconazole-associated severe hyponatremia

Kim KH, Lee SH, Lee SW, Yun NR, Kim NJ, Yu KS, Jang IJ, Park WB, Oh MD.

Med Mycol J 2012,Jan;50(1):103-5
530

Evaluation of the pharmacokinetic interaction between the dipeptidyl peptidase IV inhibitor LC15-0444 and pioglitazone in healthy volunteers

Kim SE, Yi SJ, Shin KH, Kim TE, Kim MJ, Kim YH, Yoon SH, Cho JY, Shin SG, Jang IJ, Yu KS.

Int J Clin Pharmacol Ther 2012,Jan;50(1):17-23
531

Effect of age on the pharmacokinetics of fimasartan (BR-A-657)

Lee HW, Lim MS, Seong SJ, Lee J, Park J, Seo JJ, Cho JY, Yu KS, Yoon YR.

Expert Opin Drug Metab Toxicol 2011,Nov;7(11):1337-44
532

The effect of the newly developed angiotensin receptor II antagonist fimasartan on the pharmacokinetics of atorvastatin in relation to OATP1B1 in healthy male volunteers

Shin KH, Kim TE, Kim SE, Lee MG, Song IS, Yoon SH, Cho JY, Jang IJ, Shin SG, Yu KS.

J Cardiovasc Pharmacol 2011,Nov;58(5):492-9
533

Imunogenicity and safety of a single intramuscular dose of a diphtheria-tetanus toxoid (Td) vaccine (GC1107) in Korean adults

Lee S, Park WB, Shin KH, Ahn DH, Yoon SH, Cho JY, Shin SG, Jang IJ, Yu KS.

Vaccine 2011,Oct;29(44):7638-43.
534

Prolonged use of aspirin alters human and rat intestinal cells and thereby limits the absorption of clopidogrel

Jung KH, Chu K, Lee ST, Yoon HJ, Chang JY, Nam WS, Yoon SH, Cho JY, Yu KS, Jang IJ, Kim M, Lee SK, Roh JK.

Clin Pharmacol Ther 2011,Oct;90(4):612-9
535

Population pharmacokinetic analysis and dosing regimen optimization of aprotinin in neonates and young infants undergoing cardiopulmonary bypass

Tae YM, Kwak JG, Kim BH, Jang IJ, Kim WH.

J Clin Pharmacol 2011,Aug;51(8):1163-76
536

Effect of CYP2C19 polymorphism on the pharmacokinetics of voriconazole after single and multiple doses in healthy volunteers

Lee SH, Kim BH, Nam WS, Yoon SH, Cho JY, Shin SG, Jang IJ, Yu KS.

J Clin Pharmacol 2011,Jul;[Epub ahead of print]
537

Pharmacokinetic profiles of ceftazidime after intravenous administration in patients undergoing automated peritoneal dialysis

Kim K, Hwang YH, Ro H, Oh YK, Kim MG, Yu KS, Shin KH, Jang IJ, Shin SG, Ann C, Oh KH.

Antimicrob 2011,Jun;55(6):2523-7. Epub 2011 Mar 14.
538

Pharmacokinetic Interaction of fimasartan, a new angiotensin II receptor antagonist, with amlodipine in healthy volunteers

Yi SJ, Kim TE, Yoon SH, Cho JY, Shin SG, Jang IJ, Yu KS.

J Cardiovasc Pharmacol 2011,Jun;57(6):682-9
539

Positive and negative associations of HLA class I alleles with allopurinol-induced SCARs in Koreans

Kang HR, Jee YK, Kim YS, Lee CH, Jung JW, Kim SH, Park HW, Chang YS, Jang IJ, Cho SH, Min KU, Kim SH, Lee KW.

Pharmacogenet Genomics 2011,May;21(5):303-7.
540

Effect of multiple doses of fimasartan, an angiotension II receptor antagonist, on the steady-state pharmacokinetics of digoxin in healthy volunteers

Yi SJ, Kim JW, Kim TE, Kim J, Jun YK, Choi J, Yoon SH, Cho JY, Song SH, Shin SG, Jang IJ, Yu KS.

Int J Clin Pharmacol Ther 2011,May;49(5):321-7
541

Effects of pregnane X receptor (NR1I2) and CYP2B6 genetic polymorphisms on the induction of bupropion hydroxylation by rifampin

Chung JY, Cho JY, Lim HS, Kim JR, Yu KS, Lim KS, Shin SG, Jang IJ.

Drug Metab Dispos 2011,Jan; 39(1):92-7
542

The potential inhibitory effect of revaprazan, an acid pump antagonist, on anticoagulation with warfarin

Jung JW, Kang HR, Kwon JW, Kim TE, Lee SH, Hong KS, Yu KS, Cho SH. Tohoku

J Exp Med 2011,Jan;224(4):293-300
543

Verification of biomarkers for diabetic retinopathy by multiple reaction monitoring

Kim K, Kim SJ, Yu HG, Yu J, Park KS, Jang IJ, Kim Y.

J Proteome Res 2010,Feb;(2).9(2):689-699
544

건강자원자에서 LB80380 경구 투여 후 LB80380, LB80920, LB80331 의 약동학적 특성 및 안전성에 관한 연구

김성은, 신광희, 김태은, 이승환, 김보형, 김민정, 윤서현, 조주연, 신상구, 장인진, 유경상

임상약리학회지 2010,Jan;18(1):34-42
545

건강한 한국인 자원자에서 Garenoxacin 단회투여에 의한 약동학적 특성 연구

신동훈, 홍정화, 이소정, 김태은, 장인진, 신상구, 유경상.

임상약리학회지 2010,Jan;18(1):43-52
546

건강한 한국인 자원자에서 나프토피딜(Naftopidil) 단회 경구투여에 의한 약동학적 특성 및 내약성에 관한 연구

차유정, 김정원, 전혜원, 신광희, 이승환, 장인진, 신상구, 유경상.

임상약리학회지 2010,Jan;18(2):127-136
547

건강한 한국인 자원자에서 테오브로민(Theobromine) 500mg 캡슐 반복 투여에 의한 안전성 및 약동학 평가에 관한 연구

김정원, 신광희, 이소정, 김태은, 오세을, 윤서현, 조주연, 유경상, 장인진, 신상구.

임상약리학회지 2010,Jan;18(1):15-22
548

실로스타졸과 은행엽 엑스의 복합제 투여 및 병용투여시 약동학적 특성 및 안전성 비교

전혜원; 이소정, 김성은, 김보형, 임경수, 이봉용, 유경상, 신상구, 장인진.

임상약리학회지 2010,Jan;18(1):5-14
549

Clinical usefulness of serum cystatin C and the pertinent estimation of glomerular filtration rate based on cystatin C

Cha RH, Lee CS, Lim YH, Kim H, Lee SH, Yu KS, Kim YS.

Nephrology (Carlton) 2010,Jan;15(8): 768-776
550

Relative bioavailability and tolerability of two formulations of bicalutamide 50-mg tablets: a randomized-sequence, open-label, two-period crossover study in healthy Korean male subjects

Lee S, Yoon SH, Cho JY, Shin SG, Jang IJ, Yu KS.

Clin Ther. 2010,Jan;32(14): 2496-2501
551

Ethnic coefficients for glomerular filtration rate estimation by the modification of diet in renal disease study equations in the Korean population

Lee CS, Cha RH, Lim YH, Kim H, Song KH, Gu N, Yu KS, Lim CS, Han JS, Kim S, Kim YS.

J Korean Med Sci 2010,Jan;25: 1616-1625
552

Pharmacokinetic and pharmacodynamic comparison of two recombinant human erythropoietin formulations after single subcutaneous administration: an open-label, sequence-randomized, two-treatment crossover study in healthy Korean male volunteers

Kim TE, Kim KP, Kim BH, Shin SG, Jang IJ, Yu KS.

Clin Ther 2010,Jan;32: 1968-1976
553

Comparison of the bioavailability and tolerability of fixed-dose combination glimepiride/metformin 2/500-mg tablets versus separate tablets: a single-dose, randomized-sequence, open-label, two-period crossover study in healthy Korean volunteers

Gu NY, Kim BH, Rhim H, Chung JY, Kim JR, Shin HS, Yoon SH, Cho JY, Shin SG, Jang IJ, Yu KS.

Clin Ther 2010,Jan;32: 1408-1418
554

Changes in the QTc interval after administration of flecainide acetate, with and without coadministered paroxetine, in relation to cytochrome P450 2D6 genotype: data from an open-label, two-period, single-sequence crossover study in healthy Korean male subjects

Lim KS, Jang IJ, Kim BH, Kim J, Jeon JY, Tae YM, Yi S, Eum S, Cho JY, Shin SG, Yu KS.

Clin Ther 2010,Jan;32(4): 659-666
555

Effect of ketoconazole on the pharmacokinetics of udenafil in healthy Korean subjects

Shin KH, Chung YJ, Kim BH, Kim TE, Kim HS, Cho JY, Jang IJ, Shin SG, Yu KS.

Brit J Clin Pharmacol 2010,Jan;69(6): 307-310
556

Influence of Ginkgo biloba extract on the pharmacodynamic effects and pharmacokinetic properties of ticlopidine: an open-label, randomized, two-period, two-treatment, two-sequence, single-dose crossover study in healthy Korean male volunteers

Kim BH, Kim KP, Lim KS, Kim JR, Yoon SH, Cho JY, Lee YO, Lee KH, Jang IJ, Shin SG, Yu KS.

Clin Ther 2010,Jan;32(2): 380-390
557

Pharmacodynamic (hemodynamic) and pharmacokinetic comparisons of S-amlodipine gentisate and racemate amlodipine besylate in healthy Korean male volunteers: two double-blind, two double-blind, randomized, two-period, two-treatment, randomized, two-period, two-treatment, two-sequence, double-dummy, single-dose crossover studies

Kim BH,Kim JR, Kim MG, Kim KP, Lee BY, Jang IJ, Shin SG, Yu KS.

Clin Ther 2010,Jan;32(1): 193-205
558

한국인 건강 피험자에서 Cytochrome P450 2C19 유전적다형성과 Ketoconazole 병용투여가 Clopidogrel 투여 후 혈소판응집 반응에 미치는 영향

김정렬, 김선정, 김화숙, 엄소영, 신광희, 조주연, 유경상, 신상구, 장인진.

대한임상약리학회지 2009,Jan;17(1):51-60
559

건강한 한국인 자원자에서 말레인산 이르소글라딘의 약동학적 특성에 관한 연구

이승환, 임경수, 김정렬, 김재우, 김보형, 조주연, 윤서현, 신상구, 장인진, 유경상.

대한임상약리학회지 2009,Jan;17(1):35-43
560

Population pharmacokinetics of artesunate and dihydroartemisinin following single- and multiple-dosing of oral artesunate in healthy subjects

Tan B, Naik H, Jang IJ, Yu KS, Kirsch LE, Shin CS, Craft JC, Fleckenstein L.

Malar J 2009,Jan;8(1): 304
561

Pharmacokinetics and pharmacodynamics of LC15-0444, a novel dipeptidyl peptidase IV inhibitor, after multiple dosing in healthy volunteers

Lim KS, Cho JY, Kim BH, Kim JR, Kim HS, Kim DK, Kim SH, Yim HJ, Lee SH, Shin SG, Jang IJ, Yu KS.

Br J Clin Pharmacol 2009,Jan;68(6): 883-90
562

The effects of ketoconazole and rifampicin on the pharmacokinetics of mirodenafil in healthy Korean male volunteers: an open-label, one-sequence, three-period, three-treatment crossover study

Shin KH, Kim BH, Kim TE, Kim JW, Yi SJ, Yoon SH, Cho JY, Shin SG, Jang IJ, Yu KS.

Clin Ther 2009,Jan;3009-3020
563

Comparative pharmacokinetic evaluation of two formulations of bicalutamide 50-mg tablets: an open-label, randomized-sequence, single-dose, two-period crossover study in healthy Korean male volunteers

Lee SH, Chung YJ, Kim BH, Shim JH, Yoon SH, Shin SG , Jang IJ, Yu KS.

Clin Ther 2009,Jan;3000-3008
564

Pharmacokinetic comparison of a new glimepiride 1-mg + metformin 500-mg combination tablet formulation and a glimepiride 2-mg + metformin 500-mg combination tablet formulation: a single- dose, randomized, open-label, two-period, two-way crossover study in healthy, fasting Korean male volunteers

Kim BH, Shin KH, KIm JW, Lim KS, Kim KP, Kim JR, Cho JY, Shin SG, Jang IJ, Yu KS.

Clin Ther 2009,Jan;2755-2764
565

Potential interactions between cilostazol and probucol: a two-part, single-dose, open-label study in healthy Korean male volunteers

Kim KP, Kim BH, Lim KS, Kim TE, Shin SG, Jang IJ, Yu KS.

Clin Ther 2009,Jan;31(10): 2098-106
566

Pharmacokinetics of intravenous piperacillin administration in patients undergoing on-line hemodiafiltration

Oh KH, Kim C, Lee H, Lee H, Jung JY, Kim NJ, Yu KS, Shin KH, Jang IJ, Ahn C.

Antimicrob Agents Chemother 2009,Jan;53(8): 3266-8
567

Effect of food on the pharmacokinetics of the oral phosphodiesterase 5 inhibitor udenafil for the treatment of erectile dysfunction

Kim TE, Kim BH, Kim JR, Lim KS, Hong JH, Kim KP, Kim HS, Shin SG, Jang IJ, Yu KS.

Br J Clin Pharmacol 2009,Jan;68(1): 43-6
568

Influence of alcohol on the hemodynamic effects and pharmacokinetic properties of mirodenafil: a single-dose, randomized-sequence, open-label, crossover study in healthy male volunteers in Korea

Kim BH, Yi S, Kim J, Lim KS, Kim KP, Lee B, Shin SG, Jang IJ, Yu KS.

Clin Ther 2009,Jan;31(6): 1234-43
569

Comparison of The pharmacokinetics of ticlopidine between administration of a combined fixed-dose tablet formulation of ticlopidine 250 mg/ginkgo extract 80 mg, and concomitant administration of ticlopidine 250-mg and ginkgo extract 80-mg tablets: An open-label, two-treatment, single-dose, randomized-sequence crossover study in healthy korean male volunteers

Kim TE, Kim BH, Kim J, Kim KP, Yi S, Shin HS, Lee YO, Lee KH, Shin SG, Jang IJ, Yu KS.

Clin Ther 2009,Jan;31(10): 2249-57
570

Effects of angelicae tenuissima radix, angelicae dahuricae radix and scutellariae radix extracts on cytochrome P450 activities in healthy volunteers

Yi S, Cho JY, Lim KS, Kim KP, Kim J, Kim BH, Hong JH, Jang IJ, Shin SG, Yu KS.

Basic Clin Pharmacol Toxicol 2009,Jan;105: 249-256
571

An open-label, single-dose, parallel-group, dose-increasing study comparing the pharmacokinetics and tolerability of pilsicainide hydrochloride in healthy Korean and Japanese male subjects

Kim BH, Kim JR, Lim KS, Kim JW, Kim KP, Hong JH, Jang IJ, Shin SG, Yu KS, Tanaka T.

Clin Ther 2009,Jan;31(3): 609-618
572

Lack of association between ABCB1, ABCG2, and ABCC2 genetic polymorphisms and multidrug resistance in partial epilepsy

Kim DW, Lee SK, Chu K, Jang IJ, Yu KS, Cho JY, Kim SJ.

Epilepsy Res 2009,Jan;84(1): 86-90
573

Genetic polymorphisms of drug-metabolizing enzymes and anti-TB drug-induced hepatitis

Kim SH, Kim SH, Bahn JW, Kim YK, Chang YS, Shin ES, Kim YS, Park JS, Kim BH, Jang IJ, Song J, Kim SH, Park HS, Min KU, Jee YK.

Pharmacogenomics 2009,Jan;10(11): 1767-79
574

Optimal dose of intravenous pantoprazole in patients with peptic ulcer bleeding requiring endoscopic hemostasis in Korea

Choi KD, Kim N, Jang IJ, Park YS, Cho JY, Kim JR, Shin JM, Jung HC, Song IS.

J Gastroenterol Hepatol 2009,Jan;24(10): 1617-24
575

Synergistic anti-tumor efficacy of lovastatin and protein kinase C-beta inhibitor in hepatocellular carcinoma

Kim W, Yoon JH, Kim JR, Jang IJ, Bang YJ, Kim YJ, Lee HS.

Cancer Chemother Pharmacol 2009,Jan;64(3): 497-507
576

Association between tumor necrosis factor alpha 308G/a polymorphism and increased proinflammatory cytokine release after cardiac surgery with cardiopulmonary bypass in the Korean population

Yoon SZ, Jang IJ, Choi YJ, Kang MH, Lim HJ, Lim YJ, Lee HW, Chang SH, Yoon SM.

J Cardiothorac Vasc Anesth 2009,Jan;23(5): 646-50
577

Pharmacokinetics of hydroxychloroquine and its clinical implications in the chemoprophylaxis malaria caused by plasmodium vivax

Lim HS, Im JS, Cho JY, Bae KS, Klein TA, Yeom JS, Kim TS, Choi JS, Jang IJ, Park JW.

Antimicrob Agents Chemother 2009,Jan;(4)
578

Gastroprotective action of cochinchina momordica seed extract is medicted by activation of CGRP and inhibition of cPla(2)/5-LOX pathway

Kang JM, Kim N, Kim B, Kim JH, Lee BY, Park JH, Lee MK, Lee HS, Jang IJ, Kim JS, Jung HC, Song IS

Dig Dis Sci 2009,Jan;(1)
579

Duplex pyrosequencing assay of the 388A>G and 521T>C SLCO1B1 polymorphisms in three asian populations

Kim EY, Cho DY, Shin HJ, Lee SS, Shon JH, Shin JG, Shin SG.

Clin Chim Acta 2008,Feb;388(1-2):68-72
580

기존제형 S-amlodipine gentisate 에 대한 변경제형 S-amlodipine gentisate 의 생물학적동등성 연구

최윤정, 김민걸, 김보형, 유경상, 장인진, 신상구.

대한임상약리학회지 2008,Jan;16(1):37-44
581

한국인 소아에서 반코마이신의 집단약동학에 관한 연구

전지영, 김정렬, 임경수, 정용주, 유경상, 장인진, 신상구.

대한임상약리학회지 2008,Jan;16(1):21-36
582

Taq1A polymorphism in the dopamine D2 receptor gene as a predictor of clinical response to aripiprazole

Kwon JS, Kim E, Kang DH, Choi JS, Yu KS, Jang IJ, Shin SG, Aplus Study Group.

Eur Neuropsychopharmacol 2008,Jan;18(12): 897-907
583

Population pharmacokinetic modelling of aripiprazole and its active metabolite, dehydroaripiprazole, in psychiatric patients

Kim JR, Seo HB, Cho JY, Kang DH, Kim YK, Bahk YM, Yu KS, Shin SG, Kwon JS, Jang IJ.

Brit J Clin Pharmacol 2008,Jan;66(6): 802-810
584

Pharmacokinetic interaction of flecainide and paroxetine in relation to the CYP2D6*10 allele in healthy Korean subjects

Lim KS, Cho JY, Jang IJ, Kim BH, Kim JW, Jeon JY, Tae YM, Yi S, Eum SY, Shin SG, Yu KS.

Brit J Clin Pharmacol 2008,Jan;66(5): 660-666
585

Pharmacokinetics, pharmacodynamics, and tolerability of the dipeptidyl peptidase IV inhibitor LC15-0444 in healthy Korean men: a dose-block-randomized, double-blind, placebo-controlled, ascending single-dose, phase I study

Lim KS, Kim JR, Choi YJ, Shin KH, Kim KP, Hong JH, Cho JY, Shin HS, Yu KS, Shin SG, Kwon OH, Hwang DM, Kim JA, Jang IJ.

Clin Ther 2008,Jan;30(10): 1817-1830
586

Pharmacokinetics/genotype associations for major cytochrome P450 enzymes in native and first- and third-generation Japanese populations: comparison with Korean, Chinese, and Caucasian populations

Myrand SP, Sekiguchi K, Man MZ, Lin X, Tzeng RY, Teng CH, Hee B, Garrett M, Kikkawa H, Lin CY, Eddy SM, Dostalik J, Mount J, Azuma J, Fujio Y, Jang IJ, Shin SG, Bleavins MR, Williams JA, Paulauskis JD, Wilner KD.

Clin Pharmacol Ther 2008,Jan;84(3): 347-361
587

Effect of the CYP2C19 polymorphism on the eradication rate of helicobacter pylori infection by 7-day triple therapy with regular proton pump inhibitor dosage

Kang JM, Kim N, Lee DH, Park YS, Kim JS, Chang IJ, Song IS, Jung HC.

J Gastroenterol Hepatol 2008,Jan;23(8): 1287-1291
588

Safety, tolerability and pharmacokinetics of Udenafil, a novel PDE-5 inhibitor, in healthy young Korean subjects

Kim BH, Lim HS, Chung JY, Kim JR, Lim KS, Sohn DR, Cho JY, Yu KS, Shin SG, Paick JS, Jang IJ.

Brit J Clin Pharmacol 2008,Jan;65(6): 660-666
589

Pharmacokinetic and pharmacodynamic interaction of lorazepam and valproic acid in relation to UGT2B7 genetic polymorphism in healthy subjects

JY Chung, JY Cho, KS Yu, JR Kim, KS Lim, DR Sohn, SG Shin, and IJ Jang.

Clin Pharmacol Ther 2008,Jan;83(4): 595-600
590

Taq1A polymorphism in the dopamine D2 receptor gene predicts brain metabolic response to aripiprazole in healthy male volunteers

Kim E, Kwon JS, Shin YW, Lee JS, Kang WJ, Jo HJ, Lee JM, Yu KS, Kang DH, Cho JY, Jang IJ, Shin SG.

Pharmacogenet Genomics 2008,Jan;18(2): 91-97
591

Identification of cytochrome P450 enzymes responsible for N-dealkylation of a new oral erectogenic, mirodenafil

Lee HS, Park EJ, Ji HY, Kim SY, Im GJ, Lee SM, Jang IJ.

Xenobiotica 2008,Jan;38(1): 21-33
592

Visualization of CYP2D6 genotype to phenotype correlation in Korean

Kim EY, Jung HJ, Lee SS, Shon JH, Shin SG, Shin JG.

AMIA Annu Symp Proc 2007,Oct;1009-10
593

약물유전학 소개

장인진

대한임상약리학회지 2007,Jan;15(1):5-19
594

신약임상개발 (Clinical development of new drugs)

유경상

Medical Postgraduates 2007,Jan;35(4):239-243
595

건강한 한국인 자원자에서 Desloratadine 단회투여에 의한 약동학적 특성 연구

이소정, 임경수, 김보형, 김재우, 김정렬, 정재용, 조주연, 유경상, 장인진, 신상구.

대한임상약리학회지 2007,Jan;15(1):46-56
596

건강한 한국인 피험자에서 베실산베포타스틴의 약동학 특성에 대한 연구

김보형, 정재용, 김정렬, 임경수, 임형석, 유경상, 장인진, 신상구.

대한임상약리학회지 2007,Jan;15(1):37-45
597

건강 피험자에서 lafutidine의 약동학 특성에 관한 연구

김보형, 김정렬, 임경수, 김재우, 김상린, 조주연, 유경상, 장인진, 신상구.

대한임상약리학회지 2007,Jan;15(1):28-36
598

Clinical implications of CYP2D6 genotypes predictive of tamoxifen pharmacokinetics in metastatic breast cancer

Lim HS, Ju Lee H, Seok Lee K, Sook Lee E, Jang IJ, Ro J.

J Clin Oncology 2007,Jan;25(25): 3837-3845
599

MRP2 haplotypes confer differential susceptibility to toxic liver injury

Choi JH, Ahn BM, Yi J, Lee JH, Lee JH, Nam SW, Chon CY, Han KH, Ahn SH, Jang IJ, Cho JY, Suh Y, Cho MO, Lee JE, Kim KH, Lee MG.

Pharmacogenet Genomics 2007,Jan;17(6): 403-415
600

Dynamically simulating the interaction of midazolam and the CYP3A4 inhibitor itraconazole using individual coupled whole-body physiologically-based pharmacokinetic (WB-PBPK) models

Vossen M, Sevestre M, Niederalt C, Jang IJ, Willmann S, Edginton AN.

Theor Biol Med Model 2007,Jan;26(4): 13
601

Modeling of brain D2 receptor occupancy-plasma concentration relationships with a novel antipsychotic, YKP1358, using serial PET scan in healthy volunteers

KS Lim, JS Kwon, IJ Jang, JM Jeong, JS Lee, HW Kim, WJ Kang, JR Kim, JY Cho, E Kim, SY Yoo, SG Shin, Yu KS.

Clin Pharmacol Ther 2007,Jan;81(2): 252-258
602

Angiotensin II Type 1 receptor 1166A/C polymorphism in association with blood pressure response to exogenous angiotensin II

Lim HS, Cho JY, Oh DS, Chung JY, Hong KS, Bae KS, Yu KS, Lee KH, Jang IJ, Shin SG.

European J Clin Pharmacol 2007,Jan;63(1): 17-26
603

Comparative pharmacokinetic and bioequivalence evaluation of two formulations of morniflumate 350-mg tablets in healthy male subjects .

Lee H, Yim SV, Kim BH, Lee S.

Int J Clin Pharmacol Ther 2007,Jan;55(1):95-101. doi: 10.5414/CP202678.
604

External Validation of a Pharmacokinetic Model of Propofol for Target-Controlled Infusion in Children under Two Years Old

Sang Hwan Ji, Ji Hyun Lee, Joo Youn Cho, Hwa Suk Kim, Young Eun Jang, Eun Hee Kim, Jin Tae Kim, Hee Soo Kim

J Korean Med Sci . 2007,Jan;23;35(11):e70
605

Long-term cardiac gene expression using a coxsackieviral vector.

Byung-Kwan Lim, Jae-Ok Shin, Sang-Chol Lee, Duk-Kyung Kim, Dong-Ju Choi, Seong-Choon Choe, Kirk U Knowlton, Eun-Seok Jeon

Journal of molecular and cellular cardiology. 2005,May;38(5):745-51. doi: 10.1016/j.yjmcc.2005.02.018.
606

Myocardial injury occurs earlier than myocardial inflammation in acute experimental viral myocarditis.

Byung-Kwan Lim 1, Jae-Ok Shin, Seong-Choon Choe, Si-Wan Choi, Jin-Ok Jeong, In-Whan Seong, Duk-Kyung Kim, Eun-Seok Jeon

Experimental & molecular medicine. 2005,Feb;28;37(1):51-7. doi: 10.1038/emm.2005.7.
607

예방접종력이 있는 초등학생의 홍역 항체 양성률 및 기여 요인 = Seroprevalence of Measles Antibody and its Attributable Factors in Elementary Students of Routine 2-dose Schedule Era with Vaccination Record

임현술, 고운영, 양병국, 김영택, 이종구, 배근량

예방의학회지(Journal of Preventive Medicine and Public Health) 2005,Jan;Vol.38 No.4, 431-436
608

울주군에서 발생한 장출혈성대장균 감염증의 발생 원인 = Cause of Enterohemorrhagic Escherichia coli Infection in Ulju County, Korea

배근량, 이상원, 양병국, 이복권, 박재구, 황병훈, 임현술

예방의학회지(Journal of Preventive Medicine and Public Health) 2003,Jan;Vol.36 No.1, 10-84
609

Local expression of interleukin-1 receptor antagonist by plasmid DNA improves mortality and decreases myocardial inflammation in experimental coxsackieviral myocarditis

Byung-Kwan Lim, Seong-Choon Choe, Jae-Ok Shin, Seong-Hyun Ho, Jong-Mook Kim, Seung-Shin Yu, Sunyoung Kim, Eun-Seok Jeon

Circulation 2002,Mar;19;105(11):1278-81.
610

2000~2001년 홍역 유행의 역학적 특성 = Epidemiological Characteristics of Measles Outbreak in 2000~2001, Korea

이호동, 배근량, 이주영, 김소진, 고운영, 양병국, 이종구, 김문식

Infection and Chemotherapy 2002,Jan;vol.34, no.2, pp. 94-103
611

연천 지역사회를 대상으로 하는 당뇨병 환자에서의 사망률 조사 = Mortality in Adults with and without Diabetes in Yonchon , Korea

배강우, 안윤진, 박용수, 박경수, 양병국, 이홍규,

Diabetes and Metabolism Journal(Diabetes and Metabolism Journal) 2002,Jan;Vol.25 No.5, 384-398
612

1980∼1999년 기간동안 국내에서 발생한 홍역의 역학적 특성 = Survey on the Epidemiological characteristics of Measles Incidence between 1980 and 1999 Year in Korea

이호동, 배근량, 이주영, 고은영, 양병국, 유만진, 이종구, 김문식

대한감염학회(THE KOREAN SOCIETY OF INFECTIOUS DISEASES) 2002,Jan;Vol.34 No.2, 89-93
613

2001년 경상북도에서 발생한 콜레라 유행에 관한 역학조사 = Epidemiologic Investigation on an Outbreak of Cholera in Gyeongsangbuk-do, Korea, 2001

이준호, 이관, 김준철, 이상원, 고운영, 양병국, 이종구, 김문식, 임현술

예방의학회지(Journal of Preventive Medicine and Public Health) 2002,Jan;Vol.35 No.4, 295-304
614

Naringin has an antiatherogenic effect with the inhibition of intercellular adhesion molecule-1 in hypercholesterolemic rabbits.

S C Choe, H S Kim, T S Jeong, S H Bok, Y B Park

Journal of cardiovascular pharmacology. 2001,Dec;38(6):947-55. doi: 10.1097/00005344-200112000-00017.
615

Fulminant coxsackieviral myocarditis.

I W Seong, S C Choe, E S Jeon

The New England journal of medicine. 2001,Aug;2;345(5):379. doi: 10.1056/NEJM200108023450518.
616

1996년과 1999년 경기지역 초등학교 학생들에서 유행성이하선염에 대한 면역도 조사 = Seroepidemiology of Mumps IgG Antibody on Primary School Children in Kyonggi Province, 1996 and 1999

나병국, 이주영, 고운영, 이진수, 신구철, 이주연, 최보율, 기모란, 양병국, 강춘, 김우주

대한감염학회(THE KOREAN SOCIETY OF INFECTIOUS DISEASES) 2001,Jan;Vol.33 No.3.157-164.
617

2000년 전국 학동기 연령층의 홍역면역도 조사 결과

양병국

Pediatric Infection and Vaccine(Pediatr Infect Vaccine) 2001,Jan;Vol.8 No.1, 11-16
618

2000년 상반기 제주도 세균성 이질 역학조사

배종면, 이상원, 양병국, 홍성철, 배근량, 강성학

Epidemiology and Health(Korean Journal of Epidemiology) 2001,Jan;Vol.23 No.1, 80-96
619

현역 군인 발생을 중심으로 본 2000년도 국내 삼일열 말라리아 발생 현황 = Status of Vivax Malaria in the Republic of Korea in 2000

박재원, 김영아, 염준섭, 유정식, 앙병국, 채종일

대한감염학회(THE KOREAN SOCIETY OF INFECTIOUS DISEASES) 2001,Jan;Vol.33 No.4, 280-284
620

2000년도 국내 말라리아 발생의 역학적 특성 = Epidemiology of Malaria in Korea, 2000

유정식, 이경희, 고운영, 이종수, 양병국

Epidemiology and Health(Korean Journal of Epidemiology) 2001,Jan;Vol.23 No.2, 19-24
621

감염생선자수(Reproductive number)에 의한 홍역 환자수 추계

신민웅, 이진희, 이상은, 고운영, 양병국, 이호동, 이종구, 배근량, 이주영

한국조사연구학회(The Korean Association for Survey Research) 2001,Jan;Vol.2001 No. 67-76
622

Analysis of mitochondrial DNA deletions in four chambers of failing human heart: hemodynamic stress, age, and disease are important factors.

U K Kim, H S Kim, B H Oh, M M Lee, S H Kim, J J Chae, H S Choi, S C Choe, C C Lee, Y B Park

Basic research in cardiology. 2000,Apr;95(2):163-71. doi: 10.1007/s003950050178.
623

SYMPOSIUM 1 : Epidemiology of cardiovascular diseases ; 연천 지역사회를 대상으로 하는 당뇨병 환자에서의 사망률 조사

이홍규 , 배강우 , 안윤진 , 박용수 , 박경수 , 양병국

한국지질동맥경화학회 2000,Jan; 20-22(3pages)
624

Salmonella Typhi, Salmonella Enteritidis 및 Salmonella Typhimurium균에 대한 Phage typing 및 antibiogram 분석 = Phage typing and antibiogram analysis for Salmonella Typhi, Salmonella Enteritidis Salmonella Typhimurium isolated in Korea

신영학, 유정식, 오경수, 이점규, 이상원, 고운영, 양병국

국립보건연구원 2000,Jan;Vol.37 No. 358-359
625

노년기 치매와 우울증의 유병률 및 위험인자 = Prevalence and Risk Factors of Dementia and Depression in the Elderly

서국희, 김장규, 연병길, 박수경, 유근영, 양병국, 김용식, 조맹제

신경정신의학(JOURNAL OF THE KOREAN NEUROPSYCHIATRIC ASSOCIATION) 2000,Jan;Vol.39 No.5, 809-824
626

A 54 kDa cysteine protease purified from the crude extract of Neodiplostomum seoulense adult worms.

M H Choi, S C Choe, S H Lee

The Korean journal of parasitology. 1999,Mar;37(1):39-46. doi: 10.3347/kjp.1999.37.1.39.
627

보건요원 교육효과 평가

황금복, 전미순, 김태숙, 양병국, 정은경, 양숙자, 김귀향

한국간호교육학회지(The Journal of Korean academic society of nursing education) 1999,Jan;Vol.5 No.1, 118-132
628

재가암환자 요구도 조사 = Need Assessment of Home-based Cancer Patients

김태숙 ,양병국, 정은경, 박노례, 이영숙, 이영성, 이석구, 김영택, 윤영호, 허길자

한국호스피스.완화의료학회지(The Korean journal of hospice and palliative care) 1999,Jan;Vol.2 No.1, 36-45
629

Effect of red ginseng on blood pressure in patients with essential hypertension and white coat hypertension.

K H Han, S C Choe, H S Kim, D W Sohn, K Y Nam, B H Oh, M M Lee, Y B Park, Y S Choi, J D Seo, Y W Lee

The American journal of Chinese medicine. 1998,Jan;26(2):199-209. doi: 10.1142/S0192415X98000257.
630

보건분야 공무원 교육수요충족을 위한 개선방안에 대한 비용최소화방안 = Cost-Minimizing Analysis for The Alternatives improving Training Opportunities for public health workers

양병국, 배은영, 김영택

국립보건원보(The Report of National Institute of Health) 1998,Jan;Vol.35 No.,14-15
631

중증 만성정신질환자 수의 추산 : Through Two Community Surveys 두 지역사회 조사를 중심으로 = Estimation of the Size of the Severe and Persistent mentally Ill in Korea

홍진표, 김운, 배재남, 정유진, 강영호, 양병국, 김용익, 김병후, 이철, 조맹제

신경정신의학(JOURNAL OF THE KOREAN NEUROPSYCHIATRIC ASSOCIATION) 1998,Jan;Vol.37 No.2, 330-339
632

지역사회 치매환자를 위한 공공보건사업

양병국

농촌의학·지역보건(Journal of Agricultural Medicine&Community Health) 1997,Jan;Vol.22 No.1, 131-141
633

Differentiation of Korean isolates of Entamoeba histolytica from Entamoeba dispar.

S C Choe, M Lee, S K Lee, K Im, E Tannich, S H Lee, S T Hong

The Korean journal of parasitology. 1996,Mar;34(1):15-20. doi: 10.3347/kjp.1996.34.1.15.
634

정신과 환자들의 의료서비스 이용에 관한 연구 : 경기도 연천 지역에서 In Yonchon Area of Kyunggi Province = The Utilization of Health Service by Psychiatric Patients

황성혜, 홍진표, 권준수, 우종인, 김중술, 조두영, 이부영, 조맹제, 양병국, 배재남

신경정신의학(JOURNAL OF THE KOREAN NEUROPSYCHIATRIC ASSOCIATION) 1996,Jan;Vol.35 No.4. 900-909
635

경기도 연천지역에서 당뇨병의 발생률 = Incidence of Diabetes Mellitus in Yonchon County, Korea

신영수, 백희영, 김용익, 김현규, 조보연, 이홍규, 신찬수, 고창순, 김성연, 박경수, 박용수, 김원배., 오태근, 양병국

Diabetes and Metabolism Journal(Diabetes and Metabolism Journal) 1996,Jan;Vol.20 No.3, 264-272
636

공공보건의료의 현안 : 국민건강증진을 위한 지역보건사업 활성화 방안 = Public health Service as a Field to Practice Primary Care

양병국

Korean Journal of Family Medicine(Korean Journal of Family Medicine) 1996,Jan;Vol.17 No.11, 996-1003
637

산전진찰을 받지 않던 병원에서 분만한 산모의 병원을 옮긴 이유와 분만결과 = The Reasons for changing hospital of woman who delivered at the hospital where they had not received antenatal care and their delivery results

유태우, 양병국, 여에스더, 최영호, 허봉렬

Korean Journal of Family Medicine(Korean Journal of Family Medicine) 1994,Jan;Vol.15 No.9, 632-638
638

전국 가정의학과 전공의 수련내용 = A Survey of Family medicine Residency Training programs in Korea

양병국 (서울대학교병원 가정의학과) ; 이행 (서울대학교병원 가정의학과) ; 윤영호 (서울대학교병원 가정의학과) ; 조은연 (서울대학교병원 가정의학과) ; 유태우 (서울대학교병원 가정의학과) ; 허봉렬 (서울대학교병원 가정의학과)

Korean Journal of Family Medicine(Korean Journal of Family Medicine) 1993,Jan;Vol.14 No.4-5, 197-205
639

일반인의 후천성 면역결핍증(AIDS)에 대한 인식도 = AIDS-related Recognition among the General Population in Korea

조비룡, 양병국, 박훈기, 김성원, 유태우, 허봉렬

Korean Journal of Family Medicine(Korean Journal of Family Medicine) 1993,Jan;Vol.14 No.10, 670-679
640

만성 부비동염의 진단 검사로서 부비동 단순 X-선 촬영의 정확도 = Validity of PNS Plain Radiograph with Chronic Sinusitis

여에스더, 최영호, 양병국, 박훈기, 유태우, 허봉렬

Korean Journal of Family Medicine(Korean Journal of Family Medicine) 1993,Jan;Vol.14 No.10, 688-695

There are total 640 results.

Department of Clinical Pharmacology and Therapeutics of Seoul National University Hospital (SNUCPT) Room 502-3, Seoul National University College of Medicine Convergence Hall Tel : 02-740-8957FAX : 02-740-8963

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