RESEARCH
Pharmacokinetics and pharmacodynamics of intravenous dexmedetomidine in healthy Korean subjects
Lee S, Kim BH, Lim K, Stalker D, Wisemandle W, Shin SG, Jang IJ, Yu KS.
J Clin Pharm Ther 2012,Dec;37(6):698-703
Tolerability and Pharmacokinetics Following a Single Dose of Vardenafil in Healthy Korean Volunteers
Seokuee Kim, SeungHwan Lee, Kyoung Soo Lim, Hyeong-Seok Lim, Sang-Goo Shin, In-Jin Jang, and Kyung-Sang Yu
Korean Society for Clinical Pharmacology and Therapeutics 2012,Dec;20(2):125-134. Korean. Published online Dec 31, 2012. https://doi.org/10.12793/jkscpt.2012.20.2.125
Pharmacodynamic comparison of two formulations of Acarbose 100-mg tablets
Lee S, Chung JY, Hong KS, Yang SH, Byun SY, Lim HS, Shin SG, Jang IJ, Yu KS.
J Clin Pharm Ther 2012,Oct;37(5):553-7.
The effect of therapeutic drug monitoring on safety and efficacy of voriconazole in invasive fungal infections: A randomized controlled trial
Park WB, Kim NH, Kim KH, Lee SH, Nam WS, Yoon SH, Song KH, Choe PG, Kim NJ, Jang IJ, Oh MD, Yu KS.
Clin Infect Dis 2012,Oct; 55(8):1080-7.
Multiple-dose pharmacokinetics of fesoterodine sustained-release in healthy Korean volunteers
Shin D, Shin KH, Lee S, Lim KS, Cho JY, Jang IJ, Shin SG, Yu KS.
Int J Clin Pharmacol Ther 2012,Oct;50(10):722-8
Assessment of the effect of mirodenafil on the hemodynamics of healthy male korean volunteers administered tamsulosin: a randomized, double-blind, placebo-controlled, 2-period crossover study
NY Gu, JW Kim, KS Lim, KH Shin, TE Kim, BY Lee, SG Shin, IJ Jang, KS Yu.
Clin Ther 2012,Sep;34(9):1929-1939
Evaluation of the pharmacokinetics, food effect, pharmacodynamics, and tolerability of DA-1229, a dipeptidyl peptidase IV inhibitor, in healthy volunteers: first-in-human study
TE Kim, KS Lim, MK Park, SH Yoon, JY Cho, SG Shin, IJ Jang, KS Yu.
Clin Ther 2012,Sep;34(9):1986-1998
Highly variable pharmacokinetics of once-daily intravenous busulfan when combined with fludarabine in pediatric patients: phase I clinical study for determination of optimal once-daily busulfan dose using pharmacokinetic modeling
Lee JW, Kang HJ, Lee SH, Yu KS, Kim NH, Yuk YJ, Jang MK, Han EJ, Kim H, Song SH, Park KD, Shin HY, Jang IJ, Ahn HS.
Biol Blood Marrow Transplant 2012,Jun;18(6):944-50
Assessment of the analgesic effect of remifentanil using three pain models in healthy Korean volunteers: a randomized, controlled study
Kim TE, Kim KP, Shin D, Chung YJ, Price J, Mistry P, Jang IJ, Yu KS.
Basic Clin Pharmacol Toxicol 2012,Jun;110(6):518-23.
Assessment of the pharmacokinetics of co-administered metformin and lobeglitazone, a thiazolidinedione antihyperglycemic agent, in healthy subjects
Shin D, Kim TE, Yoon SH, Cho JY, Shin SG, Jang IJ, Yu KS.
Curr Med Res Opin 2012,Jun;28(7):1213-20.
The effect of fimasartan, an angiotensin receptor type 1 blocker, on the pharmacokinetics and pharmacodynamics of warfarin in healthy korean male volunteers: a one-sequence, two-period crossover clinical trial
Gu N, Kim BH, Lim KS, Kim SE, Nam WS, Yoon SH, Cho JY, Shin SG, Jang IJ, Yu KS.
Clin Ther 2012,Jun;34(7):1592-600.
Apple juice greatly reduces systemic exposure to atenolol
Jeon HW, Jang IJ, Lee S, Ohashi K, Kotegawa T, Ieiri I, Cho JY, Yoon SH, Shin SG, Yu KS, Lim KS.
Br J Clin Pharmacol 2012,May;doi: 10.1111/j.1365-2125.2012.04324.x. [Epub ahead of print]
Pharmacokinetic and pharmacodynamic properties of the calcimimetic agent cinacalcet (KRN1493) in healthy male Korean subjects: a randomized, open-label, single ascending-dose, parallel-group study
Lee S, Gu NY, Kim BH, Lim KS, Shin SG, Jang IJ, Yu KS.
Clin Ther 2012,May;34(5):1160-9.
Assessment of pharmacokinetic proportionality of levofloxacin and cyclosporine over a 100-fold dose range in healthy human volunteers
Lim MS, Seong SJ, Park J, Seo JJ, Lee J, Yu KS, Lee HW, Yoon YR.
Expert Opin Drug Metab Toxicol 2012,Apr;8(4):399-405.
Pharmacokinetics and pharmacodynamics of oral tolvaptan administered in 15- to 60-mg single doses to healthy Korean men
Yi S, Jeon H, Yoon SH, Cho JY, Shin SG, Jang IJ, Yu KS.
J Cardiovasc Pharmacol 2012,Apr;59(4):315-22.
Predicting brain occupancy from plasma levels using PET: superiority of combining pharmacokinetics with pharmacodynamics while modeling the relationship
Kim ET, Oliver D Howes, Kim BH, Jeong JM, Lee JS, Jang IJ, Shin SG, FE. Turkheimer, ST Kapur, Kwon JS.
J.Cereb. Blood Flow Metab. 2012,Apr;32(4):759-68
A positron emission tomography microdosing study with sertraline in healthy volunteers
Shin KH, Kim KP, Lim KS, Kim JW, Lee YS, Yang BY, Lee JS, Jung JM, Yoon SH, Jang IJ, Yu KS.
Int J Clin Pharmacol Ther 2012,Mar;50(3):224-32.
Frequency of CYP2C9 variant alleles, including CYP2C9*13 in a Korean population and effect on glimepiride pharmacokinetics
Lee HW, Lim MS, Lee J, Jegal MY, Kim DW, Lee WK, Jang IJ, Shin JG, Yoon YR.
J Clin Pharm Ther 2012,Feb;37(1):105-11
Effect of oseltamivir on bleeding risk associated with warfarin therapy: a retrospective review
Lee SH, Kang HR, Jung JW, Kwon JW, Hong KS, Yu KS, Cho SH.
Clin Drug Investig 2012,Feb;32(2):131-7
Tolerability and pharmacokinetics of a new P-glycoprotein inhibitor, HM30181, in healthy Korean male volunteers: single- and multiple-dose randomized, placebo-controlled studies
Kim TE, Gu N, Yoon SH, Cho JY, Park KM, Shin SG, Jang IJ, Yu KS.
Clin Ther 2012,Feb;34(2):482-94
Increased systemic exposure of fimasartan, an angiotensin II receptor antagonist, by ketoconazole and rifampicin
Kim JW, Yi S, Kim TE, Lim KS, Yoon SH, Cho JY, Lee MG, Song IS, Shin SG, Jang IJ, Yu KS.
J Clin Pharmacol 2012,Jan;[Epub ahead of print]
Pharmacokinetics of a fixed-dose glimepiride/sustained-release metformin combination
Kim KP, Lim KS, Kim BH, Shin HS, Cho JY, Shin SG, Jang IJ, Yu KS.
Int J Clin Pharmacol Ther 2012,Jan;50(2):142-9.
Pharmacokinetics of lacosamide in healthy korean male volunteers
Kim SE, Gu NY, Kim BH, Fitchner A, Elshoff JP, Cawello W, Jang IJ, Yu KS.
Pharmacol 2012,Jan;89(3-4):172-8
Comparative pharmacokinetics of HD203, a biosimilar of etanercept, with marketed etanercept (Enbrel): a double-blind, single-dose, crossover study in healthy volunteers
Yi S, Kim SE, Park MK, Yoon SH, Cho JY, Lim KS, Shin SG, Jang IJ, Yu KS.
BioDrugs 2012,Jan;26(3):177-84
Assessment of the drug-drug interactions between fimasartan and hydrochlorothiazide in healthy volunteer
Jeon HW, Lim KS, Shin KH, Kim JW, Yoon SH, Cho JY, Shin SG, Jang IJ, Yu KS.
J Cardiovasc Pharmacol 2012,Jan;59(1):84-91
Voriconazole-associated severe hyponatremia
Kim KH, Lee SH, Lee SW, Yun NR, Kim NJ, Yu KS, Jang IJ, Park WB, Oh MD.
Med Mycol J 2012,Jan;50(1):103-5
Evaluation of the pharmacokinetic interaction between the dipeptidyl peptidase IV inhibitor LC15-0444 and pioglitazone in healthy volunteers
Kim SE, Yi SJ, Shin KH, Kim TE, Kim MJ, Kim YH, Yoon SH, Cho JY, Shin SG, Jang IJ, Yu KS.
Int J Clin Pharmacol Ther 2012,Jan;50(1):17-23