SNUCPT

RESEARCH

https://cpt.snu.ac.kr/en/Research/Publication?publishedYear=2014 URL COPY

01

A bioequivalence study of two levofloxacin tablets in healthy male subjects

Chung I, Yoon S, Yi S, Kim BH, Yim SV, Jang IJ, Lee H.

Transl Clin Pharmacol 2014,Dec;22(2):102-105.
02

Verapamil decreases the glucose-lowering effect of metformin in healthy volunteers.

Cho SK, Kim CO, Park ES, Chung JY.

Br J Clin Pharmacol 2014,Dec;78(6):1426-32. doi: 10.1111/bcp.12476.
03

Evaluation of the pharmacokinetic and pharmacodynamic drug interactions between cilnidipine and valsartan, in healthy volunteers.

Lee J, Lee H, Jang K, Lim KS, Shin D, Yu KS.

Drug Des Devel Ther 2014,Oct;8:1781-8. doi: 10.2147/DDDT.S68574. eCollection 2014.
04

Multiple-dose pharmacokinetics and pharmacodynamics of evogliptin (DA-1229), a novel dipeptidyl peptidase IV inhibitor, in healthy volunteers.

Gu N, Park MK, Kim TE, Bahng MY, Lim KS, Cho SH, Yoon SH, Cho JY, Jang IJ, Yu KS.

Drug Des Devel Ther 2014,Oct;8:1709-21. doi: 10.2147/DDDT.S65678. eCollection 2014.
05

Effect of renal function on the pharmacokinetics of fimasartan: a single-dose, open-label, Phase I study.

Seokuee Kim, Jongtae Lee, Donghoon Shin, Kyoung Soo Lim, Yon Su Kim, In-Jin Jang

Drug Des Devel Ther 2014,Oct;8:1723-31. doi: 10.2147/DDDT.S68784. eCollection 2014.
06

Korean, Japanese, and Chinese populations featured similar genes encoding drug-metabolizing enzymes and transporters: a DMET Plus microarray assessment.

Yi S, An H, Lee H, Lee S, Ieiri I, Lee Y, Cho JY, Hirota T, Fukae M, Yoshida K, Nagatsuka S, Kimura M, Irie S, Sugiyama Y, Shin DW, Lim KS, Chung JY, Yu KS, Jang IJ.

Pharmacogenet Genomics 2014,Oct;24(10):477-85. doi: 10.1097/FPC.0000000000000075.
07

Trough concentration over 12.1 mg/L is a major risk factor of vancomycin-related nephrotoxicity in patients with therapeutic drug monitoring.

Han H, An H, Shin KH, Shin D, Lee S, Kim JH, Cho SH, Kang HR, Jang IJ, Yu KS, Lim KS.

Ther Drug Monit 2014,Oct;36(5):606-11. doi: 10.1097/FTD.0000000000000061.
08

Pharmacokinetic-Pharmacodynamic Relationships of Macitentan, a New Endothelin Receptor Antagonist, After Multiple Dosing in Healthy Korean Subjects.

Ahn LY, Kim SE, Yi S, Dingemanse J, Lim KS, Jang IJ, Yu KS.

Am J Cardiovasc Drugs 2014,Oct;14(5):377-85. doi: 10.1007/s40256-014-0081-4.
09

Pharmacokinetics and tolerability of the new second-generation nonnucleoside reverse- transcriptase inhibitor KM-023 in healthy subjects.

Cha YJ, Lim KS, Park MK, Schneider S, Bray B, Kang MC, Chung JY, Yoon SH, Cho JY, Yu KS.

Drug Des Devel Ther 2014,Sep;8:1613-9. doi: 10.2147/DDDT.S65596. eCollection 2014.
10

노인의 임상시험 참여에 대한 현황과 향후 발전 방향 : 임상시험 전문가를 대상으로 한 설문조사 분석

김선욱, 정희원, 박미란, 정재용, 이근욱, 김지현, 이종석, 김광일, 김철호.

J Korean Geriatr Soc 2014,Sep;18(3):122-135.
11

Effects of HM30181, a P-glycoprotein inhibitor, on the pharmacokinetics and pharmacodynamics of loperamide in healthy volunteers.

Kim TE, Lee H, Lim KS, Lee S, Yoon SH, Park KM, Han H, Shin SG, Jang IJ, Yu KS, Cho JY.

Br J Clin Pharmacol 2014,Sep;78(3):556-64. doi: 10.1111/bcp.12368.
12

Predictive performance of gentamicin dosing nomograms.

Lee J, Yoon S, Shin D, Han H, An H, Lee J, Lim KS, Yu KS, Lee H.

Drug Des Devel Ther 2014,Aug;8:1097-106. doi: 10.2147/DDDT.S66981. eCollection 2014.
13

Investigation of bioequivalence of a new fixed-dose combination of acarbose and metformin with the corresponding loose combination as well as the drug-drug interaction potential between both drugs in healthy adult male subjects.

Kim S, Jang IJ, Shin D, Shin DS, Yoon S, Lim KS, Yu KS, Li J, Zhang H, Liu Y, Brendel E, Blode H, Wang Y.

J Clin Pharm Ther 2014,Aug;39(4):424-31. doi: 10.1111/jcpt.12166. Epub 2014 May 8.
14

An assessment of the pharmacokinetics, pharmacodynamics, and tolerability of GCPGC, a novel pegylated granulocyte colony-stimulating factor (G-CSF), in healthy subjects.

Shin KH, Lim KS, Lee H, Jang IJ, Yu KS.

Invest New Drugs 2014,Aug;32(4):636-43. doi: 10.1007/s10637-014-0068-7. Epub 2014 Jan 28.
15

A Phase I Study of Oral Paclitaxel with a Novel P-Glycoprotein Inhibitor, HM30181A, in Patients with Advanced Solid Cancer.

Lee HJ, Heo DS, Cho JY, Han SW, Chang HJ, Yi HG, Kim TE, Lee SH, Oh DY, Im SA, Jang IJ, Bang YJ.

Cancer Res Treat 2014,Jul;46(3):234-42. doi: 10.4143/crt.2014.46.3.234. Epub 2014 Jul 15.
16

Tolerability and Pharmacokinetics of Lobeglitazone, a Novel Peroxisome Proliferator-Activated Receptor-γ Agonist, After a Single Oral Administration in Healthy Female Subjects.

Park MK, Kim TE, Kim J, Kim C, Yoon SH, Cho JY, Jang IJ, Yu KS, Lim KS.

Clin Drug Investig 2014,Jul;34(7):467-74. doi: 10.1007/s40261-014-0197-y.
17

Effects of proton pump inhibitors on metformin pharmacokinetics and pharmacodynamics.

Kim A, Chung I, Yoon SH, Yu KS, Lim KS, Cho JY, Lee H, Jang IJ, Chung JY.

Drug Metab Dispos 2014,Jul;42(7):1174-9. doi: 10.1124/dmd.113.055616. Epub 2014 Apr 24.
18

A rapid, simple and reliable HPLC-triple quadrupole tandem mass spectrometer method for a simultaneous quantification of irinotecan and its active metabolite 7-ethyl-10-hydroxycamptothecin (SN38) in mouse plasma.

Ahn G, Park DM, Park JW, Kim HY, Cho JY, Rhee SJ, Jang IJ, Kim HK.

Biomed Chromatogr 2014,Jul;28(7):919-22. doi: 10.1002/bmc.3134. Epub 2014 Jan 23.
19

Novel nanocrystal formulation of megestrol acetate has improved bioavailability compared with the conventional micronized formulation in the fasting state.

Jang K, Yoon S, Kim SE, Cho JY, Yoon SH, Lim KS, Yu KS, Jang IJ, Lee H.

Drug Des Devel Ther 2014,Jun;8:851-8. doi: 10.2147/DDDT.S62176. eCollection 2014.
20

Genetic Polymorphisms of the Carboxylesterase 1 (CES1)Gene in a Korean Population.

Cha YJ, Jeong HE, Shin JG, Kim EY, Yu KS, Cho JY, Yoon SH, Lim KS.

Transl Clin Pharmacol 2014,Jun;22(1):30-34.
21

Pregnane X Receptor agonist Increases the __EXPRESSION__ Levels of the Plasma Membrane Monoamine Transporter.

Cho SK, Oh H, Hong SH, Park MS, Chung JY.

Transl Clin Pharmacol 2014,Jun;22(1):19-21.
22

The Effects of Moxifloxacin on QTc Interval in Healthy Korean Male Subjects.

Moon SJ, Lee J, An H, Yim DS, Chung JY, Yu KS, Cho JY, Lim KS.

Drugs R D 2014,Jun;14(2):63-71. doi: 10.1007/s40268-014-0040-1.
23

Aspirin decreases systemic exposure to clopidogrel through modulation of p-glycoprotein but does not alter its antithrombotic activity.

Oh J, Shin D, Lim KS, Lee S, Jung KH, Chu K, Hong KS, Shin KH, Cho JY, Yoon SH, Ji SC, Yu KS, Lee H, Jang IJ.

Clin Pharmacol Ther 2014,Jun;95(6):608-16. doi: 10.1038/clpt.2014.49. Epub 2014 Feb 24.
24

Pharmacokinetic and pharmacodynamic interaction between gemigliptin and metformin in healthy subjects.

Shin D, Cho YM, Lee S, Lim KS, Kim JA, Ahn JY, Cho JY, Lee H, Jang IJ, Yu KS.

Clin Drug Investig 2014,Jun;34(6):383-93. doi: 10.1007/s40261-014-0184-3.
25

Pharmacodynamics, Pharmacokinetics, and Tolerability of Intravenous or Subcutaneous GC1113, a Novel Erythropoiesis-Stimulating Agent.

Han H, Lee J, Shin D, Shin KH, Jeon H, Lim KS, Yoon SH, Shin SG, Jang IJ, Cho JY, Yu KS.

Clin Drug Investig 2014,Jun;34(6):373-82. doi: 10.1007/s40261-014-0183-4.
26

Effect of preservation conditions on cartilage tissue for cell transplantation.

Kim BY, Nam BM, Lee KM, Jo YH, Nemeno JG, Yang W, Lee S, Kim H, Jang IJ, Takebe T, Lee JI.

Transplant Proc 2014,May;46(4):1139-44. doi: 10.1016/j.transproceed.2013.11.125.
27

Voriconazole Therapeutic Drug Monitoring is Necessary for Children with Invasive Fungal Infection.

Kang HM, Kang SY, Cho EY, Yu KS, Lee JW, Kang HJ, Park KD, Shin HY, Ahn HS, Lee H, Choi EH, Lee HJ.

Korean J Pediatr Infect Dis 2014,Apr;21(1):9-21.
28

Seasonal variation in hemoglobin a1c in korean patients with type 2 diabetes mellitus.

Kim YJ, Park S, Yi W, Yu KS, Kim TH, Oh TJ, Choi J, Cho YM.

J Korean Med Sci 2014,Apr;29(4):550-5. doi: 10.3346/jkms.2014.29.4.550. Epub 2014 Apr 1.
29

Dose selection method for pharmacokinetic study in hemodialysis patients using a subpharmacological dose: oseltamivir as a model drug.

Kim DK, Lee JW, Shin KH, Kim S, Oh KH, Kim M, Yu KS, Lee JP, Lim CS, Kim YS, Joo KW.

BMC Nephrol 2014,Mar;15:46. doi: 10.1186/1471-2369-15-46.
30

Area under the concentration-time curve to minimum inhibitory concentration ratio as a predictor of vancomycin treatment outcome in methicillin-resistant Staphylococcus aureus bacteraemia

Jung Y, Song KH, Cho JE, Kim HS, Kim NH, Kim TS, Choe PG, Chung JY, Park WB, Bang JH, Kim ES, Park KU, Park SW, Kim HB, Kim NJ, Oh MD.

Int J Antimicrob Agents 2014,Feb;43(2):179-83. doi: 10.1016/j.ijantimicag.2013.10.017. Epub 2013 Nov 18.
31

Area under the concentration-time curve to minimum inhibitory concentration ratio as a predictor of vancomycin treatment outcome in methicillin-resistant Staphylococcus aureus bacteraemia.

Jung Y, Song KH, Cho Je, Kim HS, Kim NH, Kim TS, Choe PG, Chung JY, Park WB, Bang JH, Kim ES, Park KU, Park SW, Kim HB, Kim NJ, Oh MD.

Int J Antimicrob Agents 2014,Feb;43(2):179-83. doi: 10.1016/j.ijantimicag.2013.10.017. Epub 2013 Nov 18.
32

Investigating the different mechanisms of genotoxic and non-genotoxic carcinogens by a gene set analysis.

Lee WJ, Kim SC, Lee SJ, Lee J, Park JH, Yu KS, Lim J, Kwon SW.

PLoS One 2014,Jan;9(1):e86700. doi: 10.1371/journal.pone.0086700. eCollection 2014.
33

Intraocular pharmacokinetics of ranibizumab in vitrectomized versus nonvitrectomized eyes.

Ahn SJ, Ahn J, Park S, Kim H, Hwang DJ, Park JH, Park JY, Chung JY, Park KH, Woo SJ.

Invest Ophthalmol Vis Sci 2014,Jan;55(1):567-73. doi: 10.1167/iovs.13-13054.
34

Comparative steady-state pharmacokinetic study of an extended-release formulation of itopride and its immediate-release reference formulation in healthy volunteers.

Yoon S, Lee H, Kim TE, Lee S, Chee DH, Cho JY, Yu KS, Jang IJ.

Drug Des Devel Ther 2014,Jan;8:123-8. doi: 10.2147/DDDT.S53027. eCollection 2014.
35

Development of lipidomic platform and phosphatidylcholine retention time index for lipid profiling of rosuvastatin treated human plasma

Choi JM, Kim TE, Cho JY, Lee HJ, Jung BH.

J Chromatogr B Analyt Technol Biomed Life Sci 2014,Jan;944:157-65. doi: 10.1016/j.jchromb.2013.10.029. Epub 2013 Oct 26.
36

Modified titanium implant as a gateway to the human body: the implant mediated drug delivery system.

Park YS, Cho JY, Lee SJ, Hwang CI.

Biomed Res Int 2014,Jan;801358. doi: 10.1155/2014/801358. Epub 2014 Jul 22.
37

Development of lipidomic platform and phosphatidylcholine retention time index for lipid profiling of rosuvastatin treated human plasma.

Choi JM, Kim TE, Cho JY, Lee HJ, Jung BH.

J Chromatogr B Analyt Technol Biomed Life Sci 2014,Jan;944:157-65. doi: 10.1016/j.jchromb.2013.10.029. Epub 2013 Oct 26.
38

Pharmacokinetics, Safety and Tolerability of DA-6034, an Anti-Inflammatory Agent, After Single and Multiple Oral Administrations in Healthy Volunteers.

Lee J, Shin KH, Kim JR, Lim KS, Jang IJ, Chung JY.

Clin Drug Investig 2014,Jan;34(1):37-42. doi: 10.1007/s40261-013-0147-0.
39

Quantification of human plasma-busulfan concentration by liquid chromatography-tandem mass spectrometry.

Moon SY, Lim MK, Hong S, Jeon Y, Han M, Song SH, Lim KS, Yu KS, Jang IJ, Lee JW, Kang HJ, Song J.

Ann Lab Med 2014,Jan;34(1):7-14. doi: 10.3343/alm.2014.34.1.7. Epub 2013 Dec 6.
40

Is extrapolation of the safety and efficacy data in one indication to another appropriate for biosimilars?

Lee H.

AAPS J 2014,Jan;16(1):22-6. doi: 10.1208/s12248-013-9534-y. Epub 2013 Oct 11.
41

Pharmacokinetic Properties and Effects of PT302 After Repeated Oral Glucose Loading Tests in a Dose-Escalating Study.

Gu N, Cho SH, Kim J, Shin D, Seol E, Lee H, Lim KS, Shin SG, Jang IJ, Yu KS.

Clin Ther 2014,Jan;36(1):101-14. doi: 10.1016/j.clinthera.2013.12.002. Epub 2013 Dec 27.

There are total 41 results.

Department of Clinical Pharmacology and Therapeutics of Seoul National University Hospital (SNUCPT) Room 502-3, Seoul National University College of Medicine Convergence Hall Tel : 02-740-8957FAX : 02-740-8963

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