RESEARCH
건강한 한국인 자원자에서 T-614의 단회 경구 투여 후 약동학적 특성에 대한 연구
신동성, 김보형, 김정렬, 임경수, 장인진, 신상구, 유경상.
대한임상약리학회지 2013,Dec;21(2):150-158
건강한 자원자에서 JES9501 단회 및 반복 경구투여 후 안전성 및 약동
김언혜, 김보형, 신동성, 조주연, 유경상, 장인진, 정재용.
대한임상약리학회지 2013,Dec;21(2):141-149
건강한 한국인 피험자에서 염산세프카펜 피복실 단회 경구투여 시 약동학적 특성에 관한 연구
이수진, 신광희, 차유정, 김정렬, 오달석, 조주연, 유경상, 장인진, 정재용, 임경수.
대한임상약리학회지 2013,Dec;21(2):104-112
Development and validation of a microfluidic chip-based nano-liquid chromatography-triple quadrupole tandem mass spectrometry method for a sensitive and reliable quantification of 7-ethyl-10-hydroxycamptothecin (SN38) in mouse plasma
Ahn G, Park DM, Park JW, Cho JY, Rhee SJ, Kim HY, Lee DS, Jang IJ, Kim HK.
Anal Bioanal Chem 2013,Dec;405(30):9817-24. doi: 10.1007/s00216-013-7411-2. Epub 2013 Oct 15.
Relationship between absolute neutrophil count profiles and pharmacokinetics of DA-3031, a pegylated granulocyte colony-stimulating factor (pegylated-G-CSF): a dose block-randomized, double-blind, dose-escalation study in healthy subjects
Ahn LY, Shin KH, Lim KS, Kim TE, Jeon H, Yoon SH, Cho JY, Shin SG, Jang IJ, Yu KS.
Clin Drug Investig 2013,Nov;33(11):817-24.
Evaluation of endogenous metabolic markers of hepatic CYP3A activity using metabolic profiling and midazolam clearance
Shin KH, Choi MH, Lim KS, Yu KS, Jang IJ, Cho JY.
Clin Pharmacol Ther 2013,Nov;94(5):601-9. doi: 10.1038/clpt.2013.128. Epub 2013 Jun 19.
Comparison of pharmacokinetics between new quinolone antibiotics: the zabofloxacin hydrochloride capsule and the zabofloxacin aspartate tablet
Han H, Eun Kim S, Shin KH, Lim C, Soo Lim K, Yu KS, Cho JY.
Curr Med Res Opin 2013,Oct;29(10):1349-55. doi: 10.1185/03007995.2013.825591. Epub 2013 Aug 19.
Usefulness of oral loading of oxcarbazepine suspension in selected patients with epilepsy
Kim DW, Gu N, Lee H, Jang IJ, Chu K, Yu KS, Cho JY, Yoon SH, Na HJ, Lee SK.
Int J Clin Pharmacol Ther 2013,Oct;51(10):780-6. doi: 10.5414/CP201896.
Genetic algorithm guided population pharmacokinetic model development for simvastatin, concurrently or non-concurrently co-administered with amlodipine
Chaturvedula A, Sale ME, Lee H.
J Clin Pharmacol 2013,Sep;doi: 10.1002/jcph.176. [Epub ahead of print]
Ambulatory Blood Pressure Response to Once-Daily Fimasartan: An 8-Week, Multicenter, Randomized, Double-Blind, Active-Comparator, Parallel-Group Study in Korean Patients With Mild To Moderate Essential Hypertension
Lee H, Kim KS, Chae SC, Jeong MH, Kim DS, Oh BH
Clin Ther 2013,Sep;35(9):1337-49. doi: 10.1016/j.clinthera.2013.06.021. Epub 2013 Aug 7.
GC-MS-Based Quantitative Signatures of Cytochrome P450-Mediated Steroid Oxidation Induced by Rifampicin
Moon JY, Kang SM, Lee J, Cho JY, Moon MH, Jang IJ, Chung BC, Choi MH.
Ther Drug Monit 2013,Aug;35(4):473-84. doi: 10.1097/FTD.0b013e318286ee02.
Pharmacokinetic-pharmacodynamic modelling of biomarker response to sitagliptin in healthy volunteers
Kim BH, Kim SE, Kang D, Lim KS, Kim JR, Jang IJ, Shin SG, Yoon SH, Cho JY, Yu KS.
Basic Clin Pharmacol Toxicol 2013,Aug;113(2):113-25. doi: 10.1111/bcpt.12068. Epub 2013 May 20.
Sustained Increase in the Oral Bioavailability of Loperamide after a Single Oral Dose of HM30181, a P-glycoprotein Inhibitor, in Healthy Male Subjects
Cha YJ, Lee H, Gu N, Kim TE, Lim KS, Yoon SH, Chung JY, Jang IJ, Shin SG, Yu KS, Cho JY.
Basic Clin Pharmacol Toxicol 2013,Jul;doi: 10.1111/bcpt.12108. [Epub ahead of print]
건강한 한국인 자원자에서 보글리보스 제제의 약효 동등성 평가 항목 선정을 위한 위약 대조, 단회 및 반복 투여 후 약력학 특성 비교 임상시험
장경호, 조상헌, 김정렬, 정재용, 임경수, 장인진, 유경상.
대한임상약리학회지 2013,Jun; 21(1):63-70
건강한 한국인에서 Zofenopril의 약동/약력학적 특성 및 내약성에 관한 무작위, 위약대조, 이중맹검, 평행군, 반복투여, 단계적 증량 임상연구
오재성, 이승환, 임경수, 정재용, 신상구, 장인진, 유경상.
대한임상약리학회지 2013,Jun; 21(1):52-62
건강한 자원자에서 무르페ⓡ 패치와 트라스트ⓡ 패치 투여 시 약동학적 특성 및 피부자극성을 비교 평가하기 위한 무작위배정, 공개, 2-Way 교차 임상 연구
최윤정, 김영미, 정재용, 조주연, 유경상, 장인진, 임경수.
대한임상약리학회지 2013,Jun; 21(1):41-51
Pharmacokinetic and Pharmacodynamic Effects of Prasugrel in Healthy Korean Males
Yu KS, Park KW, Kelly RP, Gu N, Payne C, Small DS, Choi HC, Kawakatsu E, Pinton P.
J Cardiovasc Pharmacol 2013,Jun;62(1):72-77.
Functional characterization of MATE2-K genetic variants and their effects on metformin pharmacokinetics
Chung JY, Cho SK, Kim TH, Kim KH, Jang GH, Kim CO, Park EM, Cho JY, Jang IJ, Choi JH.
Pharmacogenet Genomics 2013,Jun;23(7):365-73. doi: 10.1097/FPC.0b013e3283622037.
Pharmacokinetic study of single and multiple oral administrations of 2 mg dienogest in healthy Korean women
Shin D, Lee S, Lim KS, Park JS, Shin SG, Jang IJ, Yu KS.
Contraception 2013,Jun;87(6):750-5. doi: 10.1016/j.contraception.2012.10.033. Epub 2012 Dec 4.
The effect of udenafil on the hemodynamics of healthy male volunteers administered tamsulosin
Kim MG, Kim JR, Kim BH, Lim KS, Shin SG, Jang IJ, Yu KS, Cho JY.
Curr Med Res Opin 2013,Jun;29(6):685-93. doi: 10.1185/03007995.2013.792792. Epub 2013 Apr 17.
Population pharmacokinetics of theophylline in premature Korean infants
Kim SE, Kim BH, Lee S, Sohn JA, Kim HS, Cho JY, Yoon SH, Jang IJ, Yu KS, Lim KS.
Ther Drug Monit 2013,Jun;35(3):338-44. doi: 10.1097/FTD.0b013e3182866695.
The relationship between antipsychotic D2 occupancy and change in frontal metabolism and working memory : A dual [(11)C]raclopride and [(18)F]FDG imaging study with aripiprazole
Kim E, Howes OD, Turkheimer FE, Kim BH, Jeong JM, Kim JW, Lee JS, Jang IJ, Shin SG, Kapur S, Kwon JS.
Psychopharmacology (Berl) 2013,May;227(2):221-9. doi: 10.1007/s00213-012-2953-0. Epub 2012 Dec 28.
Pharmacokinetic and pharmacodynamic properties of a new long-acting granulocyte colony-stimulating factor (HM10460A) in healthy volunteers
Shin KH, Kim TE, Lim KS, Yoon SH, Cho JY, Kim SE, Park KM, Shin SG, Jang IJ, Yu KS.
BioDrugs 2013,Apr;27(2):149-58. doi: 10.1007/s40259-013-0010-0.
Exploration of optimal dosing regimens of haloperidol, a D2 Antagonist, via modeling and simulation analysis in a D2 receptor occupancy study
Lim HS, Kim SJ, Noh YH, Lee BC, Jin SJ, Park HS, Kim S, Jang IJ, Kim SE.
Pharm Res 2013,Mar;30(3):683-93. doi: 10.1007/s11095-012-0906-2. Epub 2012 Nov 10.
Global metabolomics and targeted steroid profiling reveal that rifampin, a strong human PXR activator, alters endogenous urinary steroid markers
Kim B, Moon JY, Choi MH, Yang HH, Lee S, Lim KS, Yoon SH, Yu KS, Jang IJ, Cho JY.
J Proteome Res 2013,Mar;12(3):1359-68. doi: 10.1021/pr301021p. Epub 2013 Jan 28.
Effect of dissolved oxygen in alcoholic beverages and drinking water on alcohol elimination in humans.
Rhee SJ, Chae JW, Song BJ, Lee ES, Kwon KI.
Alcohol 2013,Feb;47(1):27-30.
Impact of ABCC2, ABCG2 and SLCO1B1 Polymorphisms on the Pharmacokinetics of Pitavastatin in Humans
Oh ES, Kim CO, Cho SK, Park MS, Chung JY.
Drug Metab Pharmacokinet 2013,Jan;28(3):196-202. Epub 2012 Sep 25.
Serum cystatin C is a major predictor of vancomycin clearance in a population pharmacokinetic analysis of patients with normal serum creatinine concentrations
Chung JY, Jin SJ, Yoon JH, Song YG.
J Korean Med Sci 2013,Jan;28(1):48-54. doi: 10.3346/jkms.2013.28.1.48. Epub 2013 Jan 8.
Apple juice greatly reduces systemic exposure to atenolol
Jeon H, Jang IJ, Lee S, Ohashi K, Kotegawa T, Ieiri I, Cho JY, Yoon SH, Shin SG, Yu KS, Lim KS.
Br J Clin Pharmacol 2013,Jan;75(1):172-9. doi: 10.1111/j.1365-2125.2012.04324.x.
Increased systemic exposure of fimasartan, an angiotensin II receptor antagonist, by ketoconazole and rifampicin
Kim JW, Yi S, Kim TE, Lim KS, Yoon SH, Cho JY, Lee MG, Song IS, Shin SG, Jang IJ, Yu KS.
J Clin Pharmacol 2013,Jan;53(1):75-81. doi: 10.1177/0091270011433328. Epub 2013 Jan 24.
Pharmacokinetic Characteristics of Cefcapene Pivoxil Hydrochloride after Single Oral Administration in Healthy Korean Subjects
이수진, 신광희, 차유정, 김정렬, 오달석, 조주연, 유경상, 장인진, 정재용, 임경수
Translational and Clinical Pharmacology 2013,Jan;2013, vol.21, no.2, pp. 104-112 (9 pages) 건강한 한국인 피험자에서 염산세프카펜 피복실 단회 경구투여 시 약동학적 특성에 관한 연구
Investigation Study on Gender Difference Based on Korean Data Related to Drug Use
이수진, 이병요, 권광일
한국임상약학회지 2013,Jan;2013, vol.23, no.2, pp. 114-122 (9 pages) 의약품 사용 관련 국내 통계자료에 나타난 성별 차이 조사 연구